HitPredict

Interactor 1: SRS11 (Q05519)
Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)
Gene: SRSF11

Interactor 2: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29298432, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016607 - nuclear speck
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 484 Hs			1 953
+	Hs
		1201552 THOC2_HUMAN (224-482): 1.34e-35: 143: 22.66		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		1037838 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		984138 SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		984096 SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		1154038 NIPBL_HUMAN (208-484): 1.02e-46: 176: 14.34		NIPBL_HUMAN (485-927): 6.3e-11: 68.9: 15.90
+	Mm
		1351630 PCLO_MOUSE (2-451): 1.38e-09: 63.1: 10.20		PCLO_MOUSE (336-952): 4.64e-24: 112: 9.12
+	Hs
		1037916 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Dm
		113976 M9PB30_DROME (1-477): 2.69e-09: 62.3: 8.66		M9PB30_DROME (374-952): 2.15e-16: 87.1: 7.48
+	Hs
		1264771 TITIN_HUMAN (33-483): 2.57e-10: 65.4: 8.99		TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54