HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: CNTP1 (P78357)
Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190)
Gene: CNTNAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction GO:0017124 - SH3 domain binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 1384
+	Hs
		593964 NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14		CNTP1_HUMAN (1-1384): 0: 1081: 100.00
+	Hs
		362242 ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46		CNTP1_HUMAN (1-1384): 0: 1081: 100.00
+	Hs
		440487 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		CNTP1_HUMAN (1-1384): 0: 1081: 100.00
+	Dm
		194870 SRC42_DROME (93-215): 8.32e-11: 62.7: 16.00		CADN_DROME (675-1300): 3.59e-65: 247: 13.93
+	Hs
		987544 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		PGBM_HUMAN (563-1055): 2.04e-10: 68: 10.83
+	Hs
		987985 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		CELR3_HUMAN (539-671): 2.43e-09: 64.6: 14.19
+	Hs
		439989 LCK_HUMAN (3-202): 7.98e-34: 128: 28.44		NOTC1_HUMAN (323-1028): 1.63e-33: 143: 9.38
+	Hs
		362206 ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46		NOTC1_HUMAN (323-1028): 1.63e-33: 143: 9.38
+	Hs
		584491 VAV_HUMAN (2-60): 7.9e-14: 71.6: 42.37		NOTC1_HUMAN (323-1028): 1.63e-33: 143: 9.38
+	Hs
		463394 LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47		NOTC1_HUMAN (323-1028): 1.63e-33: 143: 9.38
+	Hs
		440038 LCK_HUMAN (3-202): 7.98e-34: 128: 28.44		NOTC2_HUMAN (323-715): 5.09e-12: 73.1: 11.03
+	Hs
		594110 NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14		CELR2_HUMAN (603-702): 3.84e-10: 66.9: 8.91
+	Hs
		594116 NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14		CELR3_HUMAN (539-671): 2.43e-09: 64.6: 14.19
+	Hs
		362389 ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46		CELR3_HUMAN (539-671): 2.43e-09: 64.6: 14.19
+	Hs
		440756 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		CELR3_HUMAN (539-671): 2.43e-09: 64.6: 14.19
+	Hs
		463472 LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47		NOTC2_HUMAN (323-715): 5.09e-12: 73.1: 11.03
+	Hs
		557479 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		CELR2_HUMAN (603-702): 3.84e-10: 66.9: 8.91