HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: DLGP4 (Q9Y2H0)
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)
Gene: DLGAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Hs			1 992
+	Hs
		154391 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		594147 NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		362417 ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		440795 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		987992 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		154384 NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		154379 ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		154403 ITSN2_HUMAN (108-216): 6.53e-13: 69.2: 18.92		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		154382 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		154398 ITSN1_HUMAN (122-216): 3.21e-11: 64.2: 23.53		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		154383 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		350653 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		594122 NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		362392 ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		440761 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		557500 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		350646 NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		350640 ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		350641 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		350644 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		DLGP3_HUMAN (1-992): 0: 986: 35.35