HitPredict

Interactor 1: RAD51 (Q06609)
DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)
Gene: RAD51

Interactor 2: RA54B (Q9Y620)
DNA repair and recombination protein RAD54B (EC 3.6.4.-) (RAD54 homolog B)
Gene: RAD54B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	18718930, 10851248, 16428451
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006312 - mitotic recombination GO:0007131 - reciprocal meiotic recombination
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 910
+	Hs
		1055552 DMC1_HUMAN (4-339): 2.94e-116: 341: 52.07		RA54B_HUMAN (1-910): 0: 819: 100.00
+	Mm
		936357 RAD51_MOUSE (1-339): 4.13e-137: 394: 98.82		RAD54_MOUSE (188-906): 0: 621: 40.22
+	Sp
		736934 RAD51_SCHPO (6-339): 1.48e-127: 371: 74.85		RAD54_SCHPO (10-905): 0: 638: 33.37
+	Hs
		988112 RAD51_HUMAN (1-339): 2.36e-137: 395: 100.00		RAD54_HUMAN (188-906): 0: 611: 39.81
+	Sp
		736936 RAD51_SCHPO (6-339): 1.48e-127: 371: 74.85		RDH54_SCHPO (82-902): 0: 632: 33.66
+	Hs
		988064 RAD51_HUMAN (1-339): 2.36e-137: 395: 100.00		CHD3_HUMAN (114-856): 0: 608: 22.86
+	Ce
		108298 G5EGG8_CAEEL (2-339): 3.9e-116: 342: 59.00		Q9U2S8_CAEEL (108-833): 0: 641: 34.93
+	Sc
		632564 RAD51_YEAST (5-339): 5.88e-117: 345: 66.57		RDH54_YEAST (50-905): 0: 631: 32.95
+	At
		955958 RAD51_ARATH (1-339): 3.65e-129: 374: 68.73		CHR25_ARATH (215-909): 0: 601: 37.04
+	Sc
		632557 RAD51_YEAST (5-339): 5.88e-117: 345: 66.57		RAD54_YEAST (239-904): 0: 618: 38.81
+	Sp
		193826 DMC1_SCHPO (16-338): 8.76e-111: 327: 48.77		RDH54_SCHPO (82-902): 0: 632: 33.66
+	Sc
		632528 DMC1_YEAST (17-339): 1.91e-109: 323: 49.38		RDH54_YEAST (50-905): 0: 631: 32.95
+	Ce
		107048 Q95Q25_CAEEL (2-339): 1.35e-117: 347: 59.00		G5EEN6_CAEEL (88-908): 0: 603: 33.89
+	Ce
		107037 G5EGG8_CAEEL (2-339): 3.9e-116: 342: 59.00		G5EEN6_CAEEL (88-908): 0: 603: 33.89
+	Sc
		632523 DMC1_YEAST (17-339): 1.91e-109: 323: 49.38		RAD54_YEAST (239-904): 0: 618: 38.81
+	Hs
		988166 RAD51_HUMAN (1-339): 2.36e-137: 395: 100.00		ARIP4_HUMAN (285-817): 5.22e-64: 237: 27.40