HitPredict

Interactor 1: CFT1 (Q06632)
Protein CFT1 (Cleavage factor two protein 1)
Gene: CFT1

Interactor 2: CFT2 (Q12102)
Cleavage factor two protein 2 (105 kDa protein associated with polyadenylation factor I)
Gene: CFT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.735

Property	Details
Experiments	12853609, 11805826, 16554755, 16429126, 37968396, 9303317
Identification Methods	affinity chromatography technology, tandem affinity purification, pull down, biochemical
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex GO:0030846 - termination of RNA polymerase II transcription, poly(A)-coupled
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1357 Sc			1 859
+	Sc
		986638 CFT1_YEAST (1-1357): 0: 1208: 100.00		YSH1_YEAST (2-430): 2.45e-134: 421: 15.86
+	At
		1323026 CPSF1_ARATH (2-1347): 0: 894: 15.45		CPSF2_ARATH (16-859): 0: 729: 21.02
+	Hs
		1014211 CPSF1_HUMAN (2-1347): 0: 791: 17.37		CPSF2_HUMAN (14-859): 0: 765: 19.40
+	Sp
		251783 CFT1_SCHPO (13-1350): 0: 868: 23.47		CFT2_SCHPO (5-859): 0: 668: 22.53
+	At
		1320907 CPSF1_ARATH (2-1347): 0: 894: 15.45		CPSF3_ARATH (10-471): 1.34e-153: 468: 16.98
+	At
		1208877 CPSF1_ARATH (2-1347): 0: 894: 15.45		CPS3B_ARATH (6-488): 1.2e-133: 413: 15.32
+	Sp
		142956 CFT1_SCHPO (13-1350): 0: 868: 23.47		YSH1_SCHPO (10-444): 8.67e-135: 421: 15.89
+	Hs
		1014217 CPSF1_HUMAN (2-1347): 0: 791: 17.37		CPSF3_HUMAN (10-468): 6.1e-151: 461: 16.99