Interactor 1: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Interactor 2: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 10567518, 7489725, 17850748, unassigned1973, 21446998
Identification Methods affinity chromatography technology, two hybrid, x-ray crystallography, two hybrid fragment pooling approach, electron microscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Agenet~Agenet, Agenet~KH_9, Agenet~Tudor_FRX1, KH_1~KH_1, KH_9~Tudor_FRX1
Common GO terms GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000775 - chromosome, centromeric region
GO:0001934 - positive regulation of protein phosphorylation
GO:0002092 - positive regulation of receptor internalization
GO:0002151 - G-quadruplex RNA binding
and 93 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024