HitPredict

Interactor 1: LYN (Q07014)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	14531861, 11137137, 22871113
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 512 Rn			1 810
+	Rn
		1144206 FGR_RAT (1-510): 0: 590: 55.06		UBC_RAT (1-810): 0: 1000: 100.00
+	Rn
		1144043 FYN_RAT (1-510): 0: 584: 53.55		UBC_RAT (1-810): 0: 1000: 100.00
+	Hs
		475292 SRC_HUMAN (1-510): 0: 592: 51.78		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		411563 LCK_HUMAN (1-512): 0: 589: 62.33		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		337319 ABL1_HUMAN (31-509): 1.57e-174: 523: 37.81		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		397850 BLK_HUMAN (1-512): 0: 556: 60.93		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69