HitPredict

Interactor 1: PP2A3 (Q07100)
Serine/threonine-protein phosphatase PP2A-3 catalytic subunit (EC 3.1.3.16) (Protein phosphatase 2A isoform 3)
Gene: PP2A3

Interactor 2: TAP46 (Q8LDQ4)
PP2A regulatory subunit TAP46 (2A phosphatase-associated protein of 46 kDa)
Gene: TAP46

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.821

Property	Details
Experiments	30833711, 21216945, unassigned1614
Identification Methods	affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Metallophos~TAP42
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 313 At			1 405
+	At
		820006 PP2A4_ARATH (1-313): 0: 549: 98.08		TAP46_ARATH (1-405): 6.6e-158: 452: 100.00
+	At
		990786 PP2A2_ARATH (6-313): 0: 531: 77.60		TAP46_ARATH (1-405): 6.6e-158: 452: 100.00
+	At
		138692 PP2A5_ARATH (10-313): 0: 527: 78.95		TAP46_ARATH (1-405): 6.6e-158: 452: 100.00
+	At
		990790 PP2A1_ARATH (13-313): 0: 525: 79.40		TAP46_ARATH (1-405): 6.6e-158: 452: 100.00
+	At
		819524 PPX1_ARATH (13-313): 0: 516: 66.34		TAP46_ARATH (1-405): 6.6e-158: 452: 100.00
+	Dm
		619912 PP2A_DROME (10-313): 0: 533: 79.93		Q9VJZ5_DROME (14-399): 3.36e-88: 273: 17.86
+	Hs
		915159 PP2AB_HUMAN (11-313): 0: 536: 80.86		IGBP1_HUMAN (11-400): 1.32e-79: 250: 22.11
+	Ce
		108339 PP2A_CAEEL (2-313): 0: 537: 75.96		PP4RS_CAEEL (1-398): 6.43e-79: 248: 19.01
+	Dm
		284474 PP4C_DROME (13-313): 0: 512: 63.25		Q9VJZ5_DROME (14-399): 3.36e-88: 273: 17.86
+	Mm
		915326 PP2AB_MOUSE (11-313): 0: 536: 80.86		IGBP1_MOUSE (15-400): 3.39e-79: 249: 21.07
+	Hs
		930801 PP2AA_HUMAN (11-313): 0: 535: 80.86		IGBP1_HUMAN (11-400): 1.32e-79: 250: 22.11
+	Mm
		930632 PP2AA_MOUSE (11-313): 0: 535: 80.86		IGBP1_MOUSE (15-400): 3.39e-79: 249: 21.07
+	Hs
		890950 PP4C_HUMAN (13-313): 0: 523: 64.90		IGBP1_HUMAN (11-400): 1.32e-79: 250: 22.11
+	Sc
		618797 PP2A1_YEAST (8-313): 0: 521: 74.27		TAP42_YEAST (17-398): 2.47e-78: 248: 19.70
+	Sc
		618860 PP2A2_YEAST (8-313): 0: 520: 75.24		TAP42_YEAST (17-398): 2.47e-78: 248: 19.70
+	Ce
		1341622 PP4C1_CAEEL (2-313): 0: 518: 62.03		PP4RS_CAEEL (1-398): 6.43e-79: 248: 19.01
+	Sp
		619311 PP2A1_SCHPO (13-313): 0: 522: 76.08		YCJ5_SCHPO (6-398): 5.67e-73: 233: 24.94
+	Sp
		619322 PP2A2_SCHPO (8-313): 0: 520: 78.18		YCJ5_SCHPO (6-398): 5.67e-73: 233: 24.94
+	Hs
		135430 PPP6_HUMAN (10-309): 1.52e-135: 388: 58.33		IGBP1_HUMAN (11-400): 1.32e-79: 250: 22.11