Protein: DACT1
Dapper homolog 1 (hDPR1) (Dapper antagonist of catenin 1) (Hepatocellular carcinoma novel gene 3 protein)

Gene: DACT1
Organism: Homo sapiens
Interactions: 35
UniProt ID: Q9NYF0

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005080 - protein kinase C binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

159885

DVL2
Segment polarity protein dishevelled homolog DVL-2

3

20

Small-scale

0.650

High

730292

1433B
14-3-3 protein beta/alpha

1

17

Small-scale

0.586

High

1110127

HDAC1
Histone deacetylase 1

2

9

Small-scale

0.584

High

1452542

DP13A
DCC-interacting protein 13-alpha

1

2

High-throughput

0.541

High

1352060

MICA1
[F-actin]-monooxygenase MICAL1

1

2

High-throughput

0.536

High

338990

CBX6
Chromobox protein homolog 6

1

0

High-throughput

0.513

High

1393325

SAHH3
Adenosylhomocysteinase 3

1

0

High-throughput

0.513

High

1452544

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

786890

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

1

Small-scale

0.508

High

995309

CSK2B
Casein kinase II subunit beta

1

4

High-throughput

0.508

High

1408396

SH3G2
Endophilin-A1

1

16

High-throughput

0.508

High

765071

CTNB1
Catenin beta-1

1

4

Small-scale

0.500

High

891831

GSK3B
Glycogen synthase kinase-3 beta

1

3

Small-scale

0.500

High

1291744

SESD1
SEC14 domain and spectrin repeat-containing protein 1

1

5

High-throughput

0.489

High

405552

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

1087594

GRSF1
G-rich sequence factor 1

1

2

Small-scale

0.481

High

181184

AXIN1
Axin-1

1

1

Small-scale

0.479

High

414733

P53
Cellular tumor antigen p53

1

3

High-throughput

0.479

High

691480

1433T
14-3-3 protein theta

1

17

Small-scale

0.479

High

730919

1433S
14-3-3 protein sigma

1

17

Small-scale

0.479

High

822886

VHL
von Hippel-Lindau disease tumor suppressor

1

1

Small-scale

0.479

High

966942

1433G
14-3-3 protein gamma

1

17

Small-scale

0.479

High

972061

1433E
14-3-3 protein epsilon

1

2

Small-scale

0.479

High

990795

1433Z
14-3-3 protein zeta/delta

1

17

Small-scale

0.479

High

1049836

1433F
14-3-3 protein eta

1

17

Small-scale

0.479

High

1452541

LEF1
Lymphoid enhancer-binding factor 1

1

7

Small-scale

0.479

High

1452543

FBW1A
F-box/WD repeat-containing protein 1A

1

2

Small-scale

0.479

High

605829

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

Small-scale

0.458

High

1094513

ZBT17
Zinc finger and BTB domain-containing protein 17

1

0

Small-scale

0.458

High

1126774

BECN1
Beclin-1

1

0

Small-scale

0.458

High

1252994

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

Small-scale

0.458

High

1337321

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

0

Small-scale

0.458

High

373325

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.445

High

1448500

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

1409728

CG025
UPF0415 protein C7orf25

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025