HitPredict

Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Interactor 2: FTM (Q68CZ1)
Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein)
Gene: RPGRIP1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26638075
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1748 Hs			1 1315
+	Hs
		148718 ZO1_HUMAN (1-1748): 0: 925: 100.00		CTRO_HUMAN (1-542): 6.86e-25: 115: 9.73
+	Hs
		990832 ZO1_HUMAN (1-1748): 0: 925: 100.00		CGNL1_HUMAN (28-613): 8.56e-13: 75.3: 14.96
+	Hs
		990961 ZO1_HUMAN (1-1748): 0: 925: 100.00		MRCKB_HUMAN (120-586): 4.94e-12: 73: 14.18
+	Hs
		1255121 DLG5_HUMAN (262-508): 3.83e-17: 90.3: 21.43		RPGR1_HUMAN (253-1313): 0: 631: 31.62
+	Rn
		92840 DLG4_RAT (1-112): 1.95e-27: 122: 29.92		CTRO_RAT (31-796): 9.82e-36: 150: 11.99
+	Mm
		823534 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		CTRO_MOUSE (111-780): 5.17e-30: 132: 10.35
+	Mm
		936586 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		ROCK2_MOUSE (165-787): 9.88e-24: 111: 10.82
+	Hs
		149079 INADL_HUMAN (60-583): 5.65e-19: 96.5: 18.77		CTRO_HUMAN (1-542): 6.86e-25: 115: 9.73
+	Hs
		1268108 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		MY18A_HUMAN (1-545): 3.87e-28: 126: 11.03
+	Hs
		149386 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		CTRO_HUMAN (1-542): 6.86e-25: 115: 9.73
+	Hs
		280085 MPDZ_HUMAN (31-489): 8.85e-18: 92.6: 13.61		DAPLE_HUMAN (64-568): 9.7e-13: 75.3: 17.26