Interactor 1: HMGB1 (P63158)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1
Interactor 2: RAGE (Q62151)
Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)
Gene: Ager
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22842346 |
| Identification Methods | enzyme linked immunosorbent assay |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HMG_box~Ig_2 |
| Common GO terms | GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005769 - early endosome GO:0006954 - inflammatory response GO:0008201 - heparin binding and 13 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
