Protein: RAGE
Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)

Gene: RAGE, AGER
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q15109

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001650 - fibrillar center
GO:0001666 - response to hypoxia
GO:0001774 - microglial cell activation
GO:0001891 - phagocytic cup

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

407626

S100B
Protein S100-B

3

9

Small-scale

0.861

High

1010255

S10AC
Protein S100-A12

2

9

Small-scale

0.768

High

682489

S100P
Protein S100-P

2

9

Small-scale

0.754

High

1142481

TLR9
Toll-like receptor 9

1

11

Small-scale

0.665

High

657034

S10A1
Protein S100-A1

1

9

Small-scale

0.647

High

686812

S10A4
Protein S100-A4

1

9

Small-scale

0.647

High

1142472

RAGE
Advanced glycosylation end product-specific receptor

1

16

Small-scale

0.647

High

481287

HMGB1
High mobility group protein B1

3

4

Small-scale

0.646

High

478465

FGF2
Fibroblast growth factor 2

1

3

Small-scale

0.618

High

541496

FGFR1
Fibroblast growth factor receptor 1

1

20

Small-scale

0.618

High

422128

A4
Amyloid-beta precursor protein

2

7

High-throughput

0.611

High

987652

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.611

High

1142473

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.580

High

230323

CREB3
Cyclic AMP-responsive element-binding protein 3

1

2

High-throughput

0.573

High

1051234

KPCZ
Protein kinase C zeta type

1

1

Small-scale

0.568

High

1142475

MAPK5
MAP kinase-activated protein kinase 5

1

5

Small-scale

0.543

High

946659

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

1

Small-scale

0.536

High

1142480

MYD88
Myeloid differentiation primary response protein MyD88

1

4

Small-scale

0.536

High

1142482

IRAK4
Interleukin-1 receptor-associated kinase 4

1

1

Small-scale

0.536

High

252453

DIAP1
Protein diaphanous homolog 1

1

5

Small-scale

0.529

High

363306

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.515

High

431816

ITB1
Integrin beta-1

1

6

High-throughput

0.515

High

1142476

MIER1
Mesoderm induction early response protein 1

1

1

High-throughput

0.515

High

389827

TTHY
Transthyretin

1

0

Small-scale

0.513

High

660264

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.493

High

1142477

CB015
Uncharacterized protein C2orf15

1

0

High-throughput

0.493

High

164343

NRP1
Neuropilin-1

1

8

High-throughput

0.479

High

375535

RASK
GTPase KRas

1

20

Small-scale

0.479

High

388629

C1QA
Complement C1q subcomponent subunit A

1

5

Small-scale

0.479

High

388715

C1QB
Complement C1q subcomponent subunit B

1

6

Small-scale

0.479

High

388778

C1QC
Complement C1q subcomponent subunit C

1

6

Small-scale

0.479

High

594005

NCK1
SH2/SH3 adapter protein NCK1

1

17

High-throughput

0.479

High

638420

FPR1
fMet-Leu-Phe receptor

1

5

Small-scale

0.479

High

668992

FPR2
N-formyl peptide receptor 2

1

5

Small-scale

0.479

High

750421

CSTF2
Cleavage stimulation factor subunit 2

1

5

High-throughput

0.479

High

951163

SC61B
Protein transport protein Sec61 subunit beta

1

3

Small-scale

0.479

High

962067

RHOA
Transforming protein RhoA

1

20

Small-scale

0.479

High

1119941

CIRBP
Cold-inducible RNA-binding protein

1

5

Small-scale

0.479

High

1142478

FBXW7
F-box/WD repeat-containing protein 7

1

2

Small-scale

0.479

High

1142474

TCAM2
TIR domain-containing adapter molecule 2

1

0

Small-scale

0.426

High

1142479

CKLF7
CKLF-like MARVEL transmembrane domain-containing protein 7

2

0

High-throughput

0.316

High

1142483

FBX10
F-box only protein 10

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025