HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: MTCL1 (Q9Y4B5)
Microtubule cross-linking factor 1 (Coiled-coil domain-containing protein 165) (PAR-1-interacting protein) (SOGA family member 2)
Gene: MTCL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	26496610, 33961781, 35271311, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005737 - cytoplasm GO:0005856 - cytoskeleton
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 1905
+	Hs
		1390764 DYL2_HUMAN (1-89): 1.69e-45: 142: 93.26		MTCL1_HUMAN (1-1905): 0: 835: 100.00
+	Hs
		322818 DYL1_HUMAN (1-89): 1.97e-46: 145: 100.00		MTCL2_HUMAN (9-1158): 6.28e-18: 93.2: 12.77
+	Hs
		322854 DYL2_HUMAN (1-89): 1.69e-45: 142: 93.26		MTCL2_HUMAN (9-1158): 6.28e-18: 93.2: 12.77
+	Hs
		587616 DYL1_HUMAN (1-89): 1.97e-46: 145: 100.00		DESP_HUMAN (294-843): 6.24e-12: 73.4: 16.70