HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: DIDO1 (Q9BTC0)
Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)
Gene: DIDO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	16189514
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 2240
+	Hs
		1084386 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		DIDO1_HUMAN (1-2240): 0: 732: 100.00
+	Hs
		1029050 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		MINT_HUMAN (10-2011): 1.36e-47: 191: 9.73
+	Hs
		993011 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		PRC2C_HUMAN (27-1904): 3.9e-50: 199: 9.83
+	Hs
		516766 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		PRC2C_HUMAN (27-1904): 3.9e-50: 199: 9.83
+	Hs
		1028876 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		1029163 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		1029046 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87
+	Hs
		993872 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		992995 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		516609 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		TITIN_HUMAN (19-1290): 3.32e-21: 104: 10.49
+	Hs
		832977 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		YLPM1_HUMAN (1365-2223): 2.36e-41: 170: 13.66
+	Hs
		516595 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		KMT2C_HUMAN (268-1949): 7.95e-19: 96.6: 10.24
+	Hs
		516749 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		952179 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		952089 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87
+	Hs
		1031405 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		TITIN_HUMAN (19-1290): 3.32e-21: 104: 10.49
+	Hs
		1084451 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		1084347 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		DC2I1_HUMAN (1961-2237): 3e-09: 64.7: 14.61