HitPredict

Interactor 1: ACTN3 (Q08043)
Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein)
Gene: ACTN3

Interactor 2: DUX4C (Q6RFH8)
Double homeobox protein 4C (Double homeobox protein 4, centromeric) (DUX4c) (Double homeobox protein 4-like protein 9)
Gene: DUX4L9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	26816005
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 901 Hs			1 374
+	Hs
		521632 ACTN1_HUMAN (19-901): 0: 687: 77.82		DUX4_HUMAN (1-374): 1.63e-53: 184: 93.63
+	Hs
		215076 ACTN3_HUMAN (1-901): 0: 680: 100.00		DUX1_HUMAN (1-168): 1.87e-39: 140: 82.14
+	Hs
		993282 ACTN3_HUMAN (1-901): 0: 680: 100.00		DUX5_HUMAN (1-168): 1.69e-35: 130: 82.14
+	Hs
		215072 ACTN2_HUMAN (13-901): 0: 663: 79.98		DUX1_HUMAN (1-168): 1.87e-39: 140: 82.14
+	Hs
		725688 ACTN2_HUMAN (13-901): 0: 663: 79.98		DUX5_HUMAN (1-168): 1.69e-35: 130: 82.14
+	Hs
		993302 ACTN3_HUMAN (1-901): 0: 680: 100.00		LHX3_HUMAN (20-265): 1.18e-13: 73.4: 17.27
+	Hs
		963445 SPTB2_HUMAN (227-791): 2.62e-11: 70: 10.78		DUX4_HUMAN (1-374): 1.63e-53: 184: 93.63
+	Dm
		962682 SPTCB_DROME (208-818): 8.01e-14: 78.1: 12.30		Q9XZC2_DROME (8-327): 1.04e-14: 77.3: 15.00
+	Dm
		111972 SPTCB_DROME (208-818): 8.01e-14: 78.1: 12.30		L0MPR7_DROME (8-286): 2.77e-11: 66.9: 17.86