HitPredict

Interactor 1: WIPF3 (A6NGB9)
WAS/WASL-interacting protein family member 3 (Corticosteroids and regional expression protein 16 homolog)
Gene: WIPF3

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 375
+	Hs
		590291 MUC1_HUMAN (83-478): 1.47e-17: 88: 12.78		ACTBL_HUMAN (2-375): 0: 734: 91.44
+	Hs
		1200982 SRCAP_HUMAN (1-467): 1.68e-09: 62.6: 13.89		ACTBL_HUMAN (2-375): 0: 734: 91.44
+	Hs
		65440 WIPF3_HUMAN (33-483): 2.92e-22: 101: 100.00		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		952739 MAP1A_HUMAN (3-454): 1.32e-21: 101: 13.27		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		952981 WIPF2_HUMAN (31-460): 3.19e-21: 98: 27.35		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		993263 WIPF2_HUMAN (31-460): 3.19e-21: 98: 27.35		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		65444 WIPF3_HUMAN (33-483): 2.92e-22: 101: 100.00		ACTC_HUMAN (2-375): 0: 594: 94.39
+	Hs
		995715 WIPF2_HUMAN (31-460): 3.19e-21: 98: 27.35		ACTC_HUMAN (2-375): 0: 594: 94.39
+	Hs
		590266 MUC1_HUMAN (83-478): 1.47e-17: 88: 12.78		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		952913 SRCAP_HUMAN (1-467): 1.68e-09: 62.6: 13.89		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		993223 SRCAP_HUMAN (1-467): 1.68e-09: 62.6: 13.89		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		995592 MDC1_HUMAN (25-481): 1.07e-11: 69.5: 10.70		ACTC_HUMAN (2-375): 0: 594: 94.39
+	Hs
		215916 SYNJ1_HUMAN (81-468): 1.1e-10: 66.4: 12.53		ACTC_HUMAN (2-375): 0: 594: 94.39
+	Dm
		534353 CPN_DROME (1-437): 9.55e-09: 59.9: 10.61		ACT5_DROME (2-375): 0: 598: 95.46
+	Hs
		995656 SRCAP_HUMAN (1-467): 1.68e-09: 62.6: 13.89		ACTC_HUMAN (2-375): 0: 594: 94.39
+	Hs
		995780 CIC_HUMAN (7-480): 6.63e-09: 60.6: 10.74		ACTC_HUMAN (2-375): 0: 594: 94.39