HitPredict

Interactor 1: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Interactor 2: IF6 (Q12522)
Eukaryotic translation initiation factor 6 (eIF-6)
Gene: TIF6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	16429126, 18467557, 16095611, 37968396
Identification Methods	affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 291 Sc			1 245
+	Hs
		880978 BRX1_HUMAN (26-286): 1.92e-85: 261: 47.91		IF6_HUMAN (1-245): 3.67e-144: 404: 72.25
+	Sc
		733992 RPF2_YEAST (6-282): 1.45e-61: 199: 16.84		IF6_YEAST (1-245): 3.82e-140: 394: 100.00
+	Sc
		755355 RPF1_YEAST (4-252): 5.84e-52: 173: 14.40		IF6_YEAST (1-245): 3.82e-140: 394: 100.00
+	Hs
		881033 SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87		IF6_HUMAN (1-245): 3.67e-144: 404: 72.25
+	Sc
		754942 SSF1_YEAST (10-197): 9.05e-34: 129: 15.64		IF6_YEAST (1-245): 3.82e-140: 394: 100.00