HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: RAPH1 (Q70E73)
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1)
Gene: RAPH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30890647
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030027 - lamellipodium GO:0030175 - filopodium
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 1250
+	Hs
		952917 ACTB_HUMAN (4-377): 0: 598: 94.12		RAPH1_HUMAN (1-1250): 0: 638: 100.00
+	Hs
		977741 ACTA_HUMAN (1-377): 0: 597: 98.41		AB1IP_HUMAN (152-716): 7.24e-145: 455: 41.25
+	Hs
		996441 ACTS_HUMAN (1-377): 0: 599: 98.94		EP300_HUMAN (534-1200): 4.99e-24: 112: 11.59
+	Hs
		952780 ACTB_HUMAN (4-377): 0: 598: 94.12		EP300_HUMAN (534-1200): 4.99e-24: 112: 11.59
+	Hs
		977683 ACTA_HUMAN (1-377): 0: 597: 98.41		EP300_HUMAN (534-1200): 4.99e-24: 112: 11.59
+	Hs
		590266 ACTA_HUMAN (1-377): 0: 597: 98.41		MUC1_HUMAN (785-1245): 3.98e-17: 89.5: 11.50
+	Hs
		995656 ACTC_HUMAN (1-377): 0: 599: 100.00		SRCAP_HUMAN (650-1249): 4.88e-12: 73.3: 13.29
+	Hs
		952913 ACTB_HUMAN (4-377): 0: 598: 94.12		SRCAP_HUMAN (650-1249): 4.88e-12: 73.3: 13.29
+	Hs
		993223 ACTG_HUMAN (4-377): 0: 598: 94.39		SRCAP_HUMAN (650-1249): 4.88e-12: 73.3: 13.29