Protein: RAPH1
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1)

Gene: RAPH1
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q70E73

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0016604 - nuclear body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

222124

NCK2
Cytoplasmic protein NCK2

4

20

High-throughput

0.892

High

1258048

DYN3
Dynamin-3

3

4

High-throughput

0.861

High

1258041

SH3G3
Endophilin-A3

2

19

Small-scale

0.819

High

1258045

ABI2
Abl interactor 2

2

12

High-throughput

0.811

High

1258043

MYO10
Unconventional myosin-X

1

4

Small-scale

0.747

High

212776

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

2

4

High-throughput

0.737

High

1258027

SRGP1
SLIT-ROBO Rho GTPase-activating protein 1

2

5

High-throughput

0.737

High

1258031

RHG12
Rho GTPase-activating protein 12

1

5

High-throughput

0.691

High

1258032

ABI1
Abl interactor 1

1

10

High-throughput

0.691

High

1258040

SH3G2
Endophilin-A1

2

17

Small-scale

0.634

High

247361

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

6

High-throughput

0.618

High

363469

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.618

High

375649

RASK
GTPase KRas

1

13

High-throughput

0.618

High

463992

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.618

High

541561

FGFR1
Fibroblast growth factor receptor 1

1

15

High-throughput

0.618

High

582850

EZRI
Ezrin

1

7

High-throughput

0.618

High

710850

EPHB2
Ephrin type-B receptor 2

1

16

High-throughput

0.618

High

955315

CDC42
Cell division control protein 42 homolog

1

13

High-throughput

0.618

High

978107

RHOB
Rho-related GTP-binding protein RhoB

1

14

High-throughput

0.618

High

988471

RAC1
Ras-related C3 botulinum toxin substrate 1

1

13

High-throughput

0.618

High

1258035

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.618

High

1258039

SH3G1
Endophilin-A2

1

18

Small-scale

0.618

High

1258049

STRAP
Serine-threonine kinase receptor-associated protein

1

10

High-throughput

0.618

High

459645

PROF1
Profilin-1

2

3

High-throughput

0.611

High

896567

VASP
Vasodilator-stimulated phosphoprotein

2

9

Small-scale

0.595

High

614700

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

2

1

High-throughput

0.584

High

889445

CLK1
Dual specificity protein kinase CLK1

1

11

High-throughput

0.579

High

594029

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.575

High

990393

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1258030

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

2

High-throughput

0.481

High

172987

XPO1
Exportin-1

1

12

High-throughput

0.479

High

242082

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

460573

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

3

High-throughput

0.479

High

529994

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.479

High

556171

CADH1
Cadherin-1

1

4

High-throughput

0.479

High

651368

CBL
E3 ubiquitin-protein ligase CBL

1

9

High-throughput

0.479

High

766648

PHB1
Prohibitin 1

1

5

Small-scale

0.479

High

786690

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

10

High-throughput

0.479

High

791482

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

845693

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.479

High

952917

ACTB
Actin, cytoplasmic 1

1

11

High-throughput

0.479

High

966514

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

986517

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

995659

ACTC
Actin, alpha cardiac muscle 1

1

9

High-throughput

0.479

High

1068246

AHNK
Neuroblast differentiation-associated protein AHNAK

1

8

High-throughput

0.479

High

1109838

HDAC1
Histone deacetylase 1

1

10

High-throughput

0.479

High

1138334

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

1141719

EEA1
Early endosome antigen 1

1

9

High-throughput

0.479

High

1152121

MARE1
Microtubule-associated protein RP/EB family member 1

1

4

High-throughput

0.479

High

1254352

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.479

High

1258028

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

1258033

ENAH
Protein enabled homolog

1

13

Small-scale

0.479

High

1258034

BICD2
Protein bicaudal D homolog 2

1

8

High-throughput

0.479

High

1258037

SH3K1
SH3 domain-containing kinase-binding protein 1

1

11

High-throughput

0.479

High

1258038

BICD1
Protein bicaudal D homolog 1

1

8

High-throughput

0.479

High

1258042

WWTR1
WW domain-containing transcription regulator protein 1

1

18

High-throughput

0.479

High

1258044

DCP1A
mRNA-decapping enzyme 1A

1

6

High-throughput

0.479

High

846356

MATR3
Matrin-3

1

5

High-throughput

0.470

High

239443

PLIN1
Perilipin-1

1

0

High-throughput

0.458

High

1258036

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.458

High

906898

GPM6A
Neuronal membrane glycoprotein M6-a

1

1

High-throughput

0.445

High

1258029

STING
Stimulator of interferon genes protein

1

3

Small-scale

0.445

High

246703

KDM1A
Lysine-specific histone demethylase 1A

1

9

High-throughput

0.437

High

1258046

XPO7
Exportin-7

1

10

High-throughput

0.437

High

1258047

RCOR1
REST corepressor 1

1

14

High-throughput

0.437

High

271331

ZBED4
Zinc finger BED domain-containing protein 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025