HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: LRRF2 (Q9Y608)
Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)
Gene: LRRFIP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30890647
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 721
+	Hs
		953217 ACTB_HUMAN (4-377): 0: 598: 94.12		LRRF2_HUMAN (1-721): 4.32e-103: 333: 100.00
+	Hs
		993404 ACTG_HUMAN (4-377): 0: 598: 94.39		LRRF2_HUMAN (1-721): 4.32e-103: 333: 100.00
+	Hs
		995626 ACTC_HUMAN (1-377): 0: 599: 100.00		LRRF1_HUMAN (280-458): 7.46e-52: 195: 56.35
+	Hs
		952864 ACTB_HUMAN (4-377): 0: 598: 94.12		LRRF1_HUMAN (280-458): 7.46e-52: 195: 56.35
+	Hs
		993201 ACTG_HUMAN (4-377): 0: 598: 94.39		LRRF1_HUMAN (280-458): 7.46e-52: 195: 56.35
+	Hs
		993257 ACTG_HUMAN (4-377): 0: 598: 94.39		DLG5_HUMAN (275-721): 9.23e-29: 125: 11.01
+	Hs
		773154 ACTC_HUMAN (1-377): 0: 599: 100.00		MYH10_HUMAN (222-720): 2.23e-18: 92.6: 11.91
+	Rn
		953311 ACTB_RAT (4-377): 0: 598: 94.12		MYH10_RAT (222-642): 2.07e-14: 79.5: 8.90
+	Hs
		995735 ACTC_HUMAN (1-377): 0: 599: 100.00		MY18A_HUMAN (332-715): 3.37e-12: 72.4: 11.16
+	Hs
		996511 ACTS_HUMAN (1-377): 0: 599: 98.94		MY18A_HUMAN (332-715): 3.37e-12: 72.4: 11.16
+	Hs
		952998 ACTB_HUMAN (4-377): 0: 598: 94.12		MY18A_HUMAN (332-715): 3.37e-12: 72.4: 11.16
+	Hs
		993275 ACTG_HUMAN (4-377): 0: 598: 94.39		MY18A_HUMAN (332-715): 3.37e-12: 72.4: 11.16
+	Rn
		953303 ACTB_RAT (4-377): 0: 598: 94.12		MYH9_RAT (331-715): 9.66e-11: 67.6: 13.51
+	Hs
		772733 ACTC_HUMAN (1-377): 0: 599: 100.00		MYH9_HUMAN (417-721): 3.17e-09: 62.9: 13.12
+	Hs
		772734 ACTS_HUMAN (1-377): 0: 599: 98.94		MYH9_HUMAN (417-721): 3.17e-09: 62.9: 13.12
+	Hs
		996460 ACTS_HUMAN (1-377): 0: 599: 98.94		ITSN1_HUMAN (532-720): 4.84e-09: 62.2: 12.44
+	Hs
		772705 ACTB_HUMAN (4-377): 0: 598: 94.12		MYH9_HUMAN (417-721): 3.17e-09: 62.9: 13.12
+	Hs
		772729 ACTG_HUMAN (4-377): 0: 598: 94.39		MYH9_HUMAN (417-721): 3.17e-09: 62.9: 13.12
+	Hs
		952844 ACTB_HUMAN (4-377): 0: 598: 94.12		ITSN1_HUMAN (532-720): 4.84e-09: 62.2: 12.44
+	Hs
		993189 ACTG_HUMAN (4-377): 0: 598: 94.39		ITSN1_HUMAN (532-720): 4.84e-09: 62.2: 12.44