Protein: LRRF1
Leucine-rich repeat flightless-interacting protein 1 (LRR FLII-interacting protein 1) (GC-binding factor 2) (TAR RNA-interacting protein)

Gene: LRRF1, LRRFIP1
Organism: Homo sapiens
Interactions: 95
UniProt ID: Q32MZ4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1093240

FLII
Protein flightless-1 homolog

7

2

Small-scale

0.751

High

701992

TMOD1
Tropomodulin-1

5

7

High-throughput

0.712

High

1181268

IFT74
Intraflagellar transport protein 74 homolog

3

3

High-throughput

0.662

High

1181286

TMOD3
Tropomodulin-3

2

7

High-throughput

0.628

High

1181287

TMOD4
Tropomodulin-4

2

7

High-throughput

0.628

High

1181292

TFR2
Transferrin receptor protein 2

2

1

High-throughput

0.611

High

573837

CCNB1
G2/mitotic-specific cyclin-B1

2

0

High-throughput

0.602

High

1181271

GA2L1
GAS2-like protein 1

2

0

High-throughput

0.602

High

1181278

TCAL2
Transcription elongation factor A protein-like 2

2

0

High-throughput

0.602

High

1181290

MCTS1
Malignant T-cell-amplified sequence 1

2

0

High-throughput

0.602

High

1181280

SH22A
SH2 domain-containing protein 2A

2

1

High-throughput

0.594

High

529904

TAU
Microtubule-associated protein tau

2

1

High-throughput

0.552

High

1181276

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.549

High

1181281

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.549

High

618695

ML12A
Myosin regulatory light chain 12A

1

4

High-throughput

0.536

High

862860

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

High-throughput

0.536

High

920449

DAPK1
Death-associated protein kinase 1

1

2

High-throughput

0.536

High

952864

ACTB
Actin, cytoplasmic 1

1

7

High-throughput

0.536

High

993201

ACTG
Actin, cytoplasmic 2

1

7

High-throughput

0.536

High

1160639

DREB
Drebrin

1

1

High-throughput

0.536

High

1181258

CENPQ
Centromere protein Q

1

1

High-throughput

0.536

High

1181261

ABRA
Actin-binding Rho-activating protein

1

1

High-throughput

0.536

High

1181267

VMP1
Vacuole membrane protein 1

1

1

High-throughput

0.536

High

1181291

HECD1
E3 ubiquitin-protein ligase HECTD1

2

1

High-throughput

0.533

High

1108872

OLIG2
Oligodendrocyte transcription factor 2

1

0

High-throughput

0.518

High

995626

ACTC
Actin, alpha cardiac muscle 1

1

7

High-throughput

0.515

High

1134600

NUMA1
Nuclear mitotic apparatus protein 1

1

1

High-throughput

0.515

High

608886

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

0

High-throughput

0.513

High

1181293

RUVB2
RuvB-like 2

1

0

High-throughput

0.513

High

843611

HD
Huntingtin

1

0

High-throughput

0.493

High

1181272

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.480

High

1181295

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

218247

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

323405

TRI37
E3 ubiquitin-protein ligase TRIM37

1

2

High-throughput

0.479

High

345896

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

378109

TNFA
Tumor necrosis factor

1

1

Small-scale

0.479

High

400918

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

537259

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

867173

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.479

High

945007

RAB25
Ras-related protein Rab-25

1

1

High-throughput

0.479

High

976299

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

980805

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

1024608

VIGLN
Vigilin

1

1

High-throughput

0.479

High

1121242

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.479

High

1123647

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.479

High

1137732

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

1161467

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1181264

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.479

High

1181265

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1181270

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.479

High

1181273

MYD88
Myeloid differentiation primary response protein MyD88

1

3

Small-scale

0.479

High

1181275

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.479

High

1181282

ANLN
Anillin

1

2

High-throughput

0.479

High

1181288

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1181289

Z3H7B
Zinc finger CCCH domain-containing protein 7B

1

2

High-throughput

0.479

High

787654

SPB5
Serpin B5

1

0

Small-scale

0.460

High

247941

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

279379

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

412027

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

431148

LA
Lupus La protein

1

0

High-throughput

0.458

High

556122

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

685599

U2AF2
Splicing factor U2AF 65 kDa subunit

1

0

High-throughput

0.458

High

791432

SYUA
Alpha-synuclein

1

0

Small-scale

0.458

High

799173

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

929963

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

957408

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

1049159

RON
Macrophage-stimulating protein receptor

1

0

High-throughput

0.458

High

1085567

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

1138271

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1181256

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1181257

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

1181259

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1181260

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

1181266

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

Small-scale

0.458

High

1181274

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.458

High

1181277

WWTR1
WW domain-containing transcription regulator protein 1

1

0

High-throughput

0.458

High

1181285

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

396230

ESR1
Estrogen receptor

1

2

High-throughput

0.445

High

765576

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

934692

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.445

High

1103202

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

1181254

CE170
Centrosomal protein of 170 kDa

1

1

High-throughput

0.445

High

598739

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

1181262

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

1181269

MTMR9
Myotubularin-related protein 9

1

0

High-throughput

0.426

High

1181279

VIAAT
Vesicular inhibitory amino acid transporter

1

0

High-throughput

0.426

High

1181283

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.426

High

1181284

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.426

High

1181296

MTCH2
Mitochondrial carrier homolog 2

1

0

High-throughput

0.426

High

95946

E7ET36
Transferrin receptor 2

1

1

High-throughput

0.407

High

106038

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1181255

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1181294

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

62535

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low

1181263

S35G3
Solute carrier family 35 member G3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025