HitPredict

Interactor 1: DSC1 (Q08554)
Desmocollin-1 (Cadherin family member 1) (Desmosomal glycoprotein 2/3) (DG2/DG3)
Gene: DSC1

Interactor 2: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 855
+	Hs
		580239 CADH2_HUMAN (23-890): 0: 728: 31.31		DDR2_HUMAN (1-855): 0: 857: 100.00
+	Hs
		994696 PCDA8_HUMAN (3-822): 0: 752: 17.28		DDR1_HUMAN (22-849): 0: 655: 52.08
+	Hs
		580228 CADH2_HUMAN (23-890): 0: 728: 31.31		DDR1_HUMAN (22-849): 0: 655: 52.08
+	Hs
		384720 DSC1_HUMAN (1-894): 0: 828: 100.00		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		971016 DSC2_HUMAN (29-894): 0: 760: 53.66		NTRK2_HUMAN (498-850): 2.17e-106: 348: 40.50
+	Hs
		385795 PCDB3_HUMAN (3-801): 0: 769: 15.63		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		384675 DSC2_HUMAN (29-894): 0: 760: 53.66		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		508294 PCDB7_HUMAN (3-798): 0: 754: 17.65		FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49
+	Hs
		508295 PCDA8_HUMAN (3-822): 0: 752: 17.28		FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49
+	Hs
		433517 PCDB3_HUMAN (3-801): 0: 769: 15.63		YES_HUMAN (556-850): 2.32e-97: 316: 34.58
+	Hs
		507842 CADH2_HUMAN (23-890): 0: 728: 31.31		FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49
+	Hs
		384238 CADH2_HUMAN (23-890): 0: 728: 31.31		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		580237 CADH2_HUMAN (23-890): 0: 728: 31.31		NTRK3_HUMAN (551-849): 3.61e-99: 329: 42.63
+	Hs
		507817 CADH1_HUMAN (23-890): 0: 699: 29.13		FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49
+	Hs
		411968 CADH1_HUMAN (23-890): 0: 699: 29.13		FYN_HUMAN (548-850): 3.85e-99: 320: 35.64
+	Hs
		433230 CADH1_HUMAN (23-890): 0: 699: 29.13		YES_HUMAN (556-850): 2.32e-97: 316: 34.58
+	Hs
		968527 PCDB3_HUMAN (3-801): 0: 769: 15.63		ROR2_HUMAN (551-854): 8.47e-56: 209: 38.39
+	Hs
		337594 PCDA7_HUMAN (3-822): 0: 759: 16.97		ABL1_HUMAN (557-846): 9.71e-55: 207: 41.03
+	Hs
		968528 PCDA8_HUMAN (3-822): 0: 752: 17.28		ROR2_HUMAN (551-854): 8.47e-56: 209: 38.39
+	Hs
		435531 CADH2_HUMAN (23-890): 0: 728: 31.31		IGF1R_HUMAN (535-845): 9.34e-58: 217: 40.13