HitPredict

Interactor 1: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	24106267
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0005829 - cytosol GO:0005884 - actin filament GO:0030027 - lamellipodium
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 1084
+	Hs
		993204 ACTG_HUMAN (4-377): 0: 605: 93.85		AMOT_HUMAN (1-1084): 2.95e-100: 343: 100.00
+	Sp
		534540 ACT_SCHPO (4-377): 0: 647: 89.04		MYO2_SCHPO (346-916): 5.31e-32: 137: 12.78
+	Hs
		993240 ACTG_HUMAN (4-377): 0: 605: 93.85		AMOL1_HUMAN (1-912): 1.21e-43: 174: 44.28
+	Hs
		903307 ACTC_HUMAN (1-377): 0: 606: 98.94		SMCA4_HUMAN (46-595): 7.56e-34: 143: 13.45
+	Hs
		903308 ACTS_HUMAN (1-377): 0: 606: 100.00		SMCA4_HUMAN (46-595): 7.56e-34: 143: 13.45
+	Hs
		903297 ACTB_HUMAN (5-377): 0: 605: 93.83		SMCA4_HUMAN (46-595): 7.56e-34: 143: 13.45
+	Hs
		903306 ACTG_HUMAN (4-377): 0: 605: 93.85		SMCA4_HUMAN (46-595): 7.56e-34: 143: 13.45
+	Hs
		772733 ACTC_HUMAN (1-377): 0: 606: 98.94		MYH9_HUMAN (358-774): 8.67e-19: 94.9: 14.38
+	Hs
		772734 ACTS_HUMAN (1-377): 0: 606: 100.00		MYH9_HUMAN (358-774): 8.67e-19: 94.9: 14.38
+	Hs
		772705 ACTB_HUMAN (5-377): 0: 605: 93.83		MYH9_HUMAN (358-774): 8.67e-19: 94.9: 14.38
+	Hs
		772729 ACTG_HUMAN (4-377): 0: 605: 93.85		MYH9_HUMAN (358-774): 8.67e-19: 94.9: 14.38
+	Hs
		773154 ACTC_HUMAN (1-377): 0: 606: 98.94		MYH10_HUMAN (389-818): 6.65e-13: 75.8: 18.35
+	Hs
		996460 ACTS_HUMAN (1-377): 0: 606: 100.00		ITSN1_HUMAN (554-1077): 9.52e-10: 65.4: 8.75
+	Hs
		995656 ACTC_HUMAN (1-377): 0: 606: 98.94		SRCAP_HUMAN (828-1033): 1.61e-09: 64.6: 21.40
+	Hs
		995587 ACTC_HUMAN (1-377): 0: 606: 98.94		DCTN1_HUMAN (510-863): 1.71e-09: 64.5: 14.85
+	Hs
		952844 ACTB_HUMAN (5-377): 0: 605: 93.83		ITSN1_HUMAN (554-1077): 9.52e-10: 65.4: 8.75
+	Hs
		993189 ACTG_HUMAN (4-377): 0: 605: 93.85		ITSN1_HUMAN (554-1077): 9.52e-10: 65.4: 8.75
+	Hs
		993223 ACTG_HUMAN (4-377): 0: 605: 93.85		SRCAP_HUMAN (828-1033): 1.61e-09: 64.6: 21.40
+	Hs
		952814 ACTB_HUMAN (5-377): 0: 605: 93.83		DCTN1_HUMAN (510-863): 1.71e-09: 64.5: 14.85
+	Hs
		993175 ACTG_HUMAN (4-377): 0: 605: 93.85		DCTN1_HUMAN (510-863): 1.71e-09: 64.5: 14.85