HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001525 - angiogenesis GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005884 - actin filament GO:0005886 - plasma membrane and 1 others more... GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Hs			1 1084
+	Hs
		952870 ACTB_HUMAN (1-375): 0: 604: 98.93		AMOT_HUMAN (1-1084): 2.95e-100: 343: 100.00
+	Hs
		772838 ACTBL_HUMAN (2-375): 0: 734: 91.44		MYH9_HUMAN (358-774): 8.67e-19: 94.9: 14.38
+	Hs
		1154094 ACTBL_HUMAN (2-375): 0: 734: 91.44		ITSN1_HUMAN (554-1077): 9.52e-10: 65.4: 8.75
+	Hs
		1200982 ACTBL_HUMAN (2-375): 0: 734: 91.44		SRCAP_HUMAN (828-1033): 1.61e-09: 64.6: 21.40
+	Hs
		993240 ACTG_HUMAN (1-375): 0: 604: 100.00		AMOL1_HUMAN (1-912): 1.21e-43: 174: 44.28
+	Mm
		993092 ACTG_MOUSE (1-375): 0: 604: 100.00		SMCA4_MOUSE (46-595): 9.38e-35: 146: 13.81
+	Hs
		903297 ACTB_HUMAN (1-375): 0: 604: 98.93		SMCA4_HUMAN (46-595): 7.56e-34: 143: 13.45
+	Hs
		903306 ACTG_HUMAN (1-375): 0: 604: 100.00		SMCA4_HUMAN (46-595): 7.56e-34: 143: 13.45
+	Hs
		903308 ACTS_HUMAN (2-375): 0: 594: 93.85		SMCA4_HUMAN (46-595): 7.56e-34: 143: 13.45
+	Sp
		534540 ACT_SCHPO (1-375): 0: 594: 91.47		MYO2_SCHPO (346-916): 5.31e-32: 137: 12.78
+	Hs
		772705 ACTB_HUMAN (1-375): 0: 604: 98.93		MYH9_HUMAN (358-774): 8.67e-19: 94.9: 14.38
+	Hs
		772729 ACTG_HUMAN (1-375): 0: 604: 100.00		MYH9_HUMAN (358-774): 8.67e-19: 94.9: 14.38
+	Hs
		772734 ACTS_HUMAN (2-375): 0: 594: 93.85		MYH9_HUMAN (358-774): 8.67e-19: 94.9: 14.38
+	Mm
		977876 ACTA_MOUSE (2-375): 0: 594: 94.39		MYH6_MOUSE (432-916): 6.83e-14: 78.8: 9.78
+	Hs
		952844 ACTB_HUMAN (1-375): 0: 604: 98.93		ITSN1_HUMAN (554-1077): 9.52e-10: 65.4: 8.75
+	Hs
		993189 ACTG_HUMAN (1-375): 0: 604: 100.00		ITSN1_HUMAN (554-1077): 9.52e-10: 65.4: 8.75
+	Hs
		952913 ACTB_HUMAN (1-375): 0: 604: 98.93		SRCAP_HUMAN (828-1033): 1.61e-09: 64.6: 21.40
+	Hs
		993223 ACTG_HUMAN (1-375): 0: 604: 100.00		SRCAP_HUMAN (828-1033): 1.61e-09: 64.6: 21.40
+	Hs
		952814 ACTB_HUMAN (1-375): 0: 604: 98.93		DCTN1_HUMAN (510-863): 1.71e-09: 64.5: 14.85
+	Hs
		993175 ACTG_HUMAN (1-375): 0: 604: 100.00		DCTN1_HUMAN (510-863): 1.71e-09: 64.5: 14.85