HitPredict

Interactor 1: GRAP (Q08012)
Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B)
Gene: drk

Interactor 2: Q9VFD3 (Q9VFD3)
Uncharacterized protein, isoform B
Gene: DmelCG42788

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22028469
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Dm			1 1560
+	Hs
		547001 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		EZRI_HUMAN (391-993): 2.54e-101: 339: 13.44
+	Mm
		804959 GRB2_MOUSE (1-210): 7.86e-65: 201: 63.08		MERL_MOUSE (372-865): 8.36e-90: 307: 12.77
+	Hs
		663972 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		PTN4_HUMAN (367-1062): 1.18e-85: 303: 14.78
+	Mm
		710138 GRB2_MOUSE (1-210): 7.86e-65: 201: 63.08		FAK1_MOUSE (389-788): 1.6e-78: 284: 17.55
+	Hs
		924501 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		FAK1_HUMAN (389-788): 1.54e-78: 284: 17.31
+	Hs
		924571 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		FAK2_HUMAN (380-732): 1.83e-71: 262: 18.38
+	Hs
		337601 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		E41L3_HUMAN (286-1113): 7.69e-89: 316: 14.63
+	Hs
		802784 CRK_HUMAN (48-209): 9e-20: 87: 29.69		E41L3_HUMAN (286-1113): 7.69e-89: 316: 14.63
+	Hs
		337358 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		PTN4_HUMAN (367-1062): 1.18e-85: 303: 14.78
+	Hs
		337606 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		TLN2_HUMAN (394-844): 1.34e-79: 294: 16.34
+	Hs
		557617 NCK1_HUMAN (5-143): 2.4e-20: 89.4: 32.35		PTN4_HUMAN (367-1062): 1.18e-85: 303: 14.78
+	Hs
		663965 CRK_HUMAN (48-209): 9e-20: 87: 29.69		PTN4_HUMAN (367-1062): 1.18e-85: 303: 14.78
+	Hs
		782778 CSK_HUMAN (2-136): 3.18e-25: 103: 36.30		FAK1_HUMAN (389-788): 1.54e-78: 284: 17.31
+	Hs
		125348 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		WWP2_HUMAN (7-376): 6.7e-46: 181: 15.98
+	Hs
		557666 NCK1_HUMAN (5-143): 2.4e-20: 89.4: 32.35		FAK1_HUMAN (389-788): 1.54e-78: 284: 17.31
+	Hs
		802571 CRK_HUMAN (48-209): 9e-20: 87: 29.69		FAK1_HUMAN (389-788): 1.54e-78: 284: 17.31
+	Hs
		337392 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		NEDD4_HUMAN (157-265): 9.32e-20: 98.7: 23.58
+	Hs
		789045 ABL2_HUMAN (4-138): 3.23e-23: 98.6: 35.71		NEDD4_HUMAN (157-265): 9.32e-20: 98.7: 23.58
+	Hs
		337535 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		NED4L_HUMAN (54-214): 1.24e-13: 78.3: 16.27
+	Hs
		789085 ABL2_HUMAN (4-138): 3.23e-23: 98.6: 35.71		NED4L_HUMAN (54-214): 1.24e-13: 78.3: 16.27