HitPredict

Interactor 1: NCBP2 (Q08920)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)
Gene: CBC2

Interactor 2: CWC2 (Q12046)
Pre-mRNA-splicing factor CWC2 (Complexed with CEF1 protein 2) (PRP19-associated complex protein 40) (Synthetic lethal with CLF1 protein 3)
Gene: CWC2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	37968396, 24500206, 21558325
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~Torus
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0045292 - mRNA cis splicing, via spliceosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 208 Sc			1 339
+	Sc
		1014931 HSH49_YEAST (41-119): 2.34e-25: 99.7: 28.75		CWC2_YEAST (1-339): 1.42e-172: 484: 100.00
+	Hs
		1020338 ELAV2_HUMAN (4-155): 3.36e-22: 94.3: 16.13		RBM22_HUMAN (5-253): 3.12e-81: 254: 20.93
+	Sc
		960476 NCBP2_YEAST (1-208): 1.82e-52: 169: 100.00		NAM8_YEAST (6-233): 3.5e-25: 107: 15.16
+	Sc
		960486 HSH49_YEAST (41-119): 2.34e-25: 99.7: 28.75		NAM8_YEAST (6-233): 3.5e-25: 107: 15.16
+	Hs
		165426 NCBP2_HUMAN (14-162): 4.13e-38: 130: 49.33		SR140_HUMAN (123-296): 1.8e-12: 70.3: 18.56
+	Hs
		165571 CSTFT_HUMAN (35-153): 4.46e-34: 129: 18.33		SR140_HUMAN (123-296): 1.8e-12: 70.3: 18.56
+	Hs
		516471 PABP1_HUMAN (47-175): 1.75e-20: 90.5: 14.60		TIAR_HUMAN (7-257): 5.64e-14: 74.1: 15.83
+	Hs
		680439 TIA1_HUMAN (41-180): 2.11e-20: 89.3: 20.00		TIAR_HUMAN (7-257): 5.64e-14: 74.1: 15.83
+	Mm
		665745 PABP1_MOUSE (47-175): 1.38e-20: 90.9: 14.60		TIA1_MOUSE (3-242): 2.16e-12: 69.1: 14.11