HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus and 1 others more... GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Hs			1 2000
+	Hs
		996673 SSRP1_HUMAN (1-709): 0: 805: 100.00		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Hs
		727856 SOX6_HUMAN (449-700): 3.73e-33: 138: 14.96		CHD3_HUMAN (1-2000): 0: 1917: 100.00
+	Hs
		225761 SOX15_HUMAN (513-702): 2.03e-33: 130: 15.10		CHD5_HUMAN (43-1961): 0: 1610: 66.45
+	Hs
		1059807 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Hs
		229376 SSRP1_HUMAN (1-709): 0: 805: 100.00		SMCA5_HUMAN (584-1612): 0: 778: 27.17
+	Hs
		658657 SSRP1_HUMAN (1-709): 0: 805: 100.00		SMCA1_HUMAN (622-1597): 0: 776: 28.08
+	Hs
		151405 SSRP1_HUMAN (1-709): 0: 805: 100.00		CHD1_HUMAN (507-1729): 0: 746: 29.81
+	Hs
		151490 SSRP1_HUMAN (1-709): 0: 805: 100.00		CHD2_HUMAN (540-1666): 0: 733: 31.02
+	Sc
		697435 POB3_YEAST (4-504): 0: 541: 29.66		CHD1_YEAST (539-1691): 0: 817: 29.78
+	Hs
		1300950 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		CHD8_HUMAN (84-1804): 0: 851: 22.96
+	Hs
		1300971 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		CHD7_HUMAN (503-1804): 0: 837: 28.86
+	Hs
		881831 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		CHD7_HUMAN (503-1804): 0: 837: 28.86
+	Hs
		818841 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		CHD7_HUMAN (503-1804): 0: 837: 28.86
+	Hs
		727934 SOX6_HUMAN (449-700): 3.73e-33: 138: 14.96		CHD7_HUMAN (503-1804): 0: 837: 28.86
+	Hs
		1332326 SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61		CHD7_HUMAN (503-1804): 0: 837: 28.86
+	Sc
		697400 RT106_YEAST (337-544): 3.23e-31: 129: 17.37		CHD1_YEAST (539-1691): 0: 817: 29.78
+	Hs
		229467 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		SMCA5_HUMAN (584-1612): 0: 778: 27.17
+	Hs
		846730 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		SMCA2_HUMAN (73-1644): 0: 718: 20.07
+	Hs
		818784 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		SMCA2_HUMAN (73-1644): 0: 718: 20.07
+	Hs
		846868 SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61		SMCA2_HUMAN (73-1644): 0: 718: 20.07