HitPredict

Interactor 1: LAMA5 (O15230)
Laminin subunit alpha-5 (Laminin-10 subunit alpha) (Laminin-11 subunit alpha) (Laminin-15 subunit alpha)
Gene: LAMA5

Interactor 2: BCAM (P50895)
Basal cell adhesion molecule (Auberger B antigen) (B-CAM cell surface glycoprotein) (F8/G253 antigen) (Lutheran antigen) (Lutheran blood group glycoprotein) (CD antigen CD239)
Gene: BCAM

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.902

Property	Details
Experiments	28514442, 33961781, 11133776, 12244066
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Ig_2~Laminin_G_1, Ig_3~Laminin_G_1
Common GO terms	GO:0005576 - extracellular region GO:0062023 - collagen-containing extracellular matrix GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 3695 Hs			1 628
+	Hs
		793285 NOTC2_HUMAN (1360-2243): 4.79e-72: 273: 12.64		MUC18_HUMAN (14-627): 1.18e-81: 271: 24.02
+	Hs
		433147 LAMB1_HUMAN (269-541): 1.34e-20: 103: 20.43		CD166_HUMAN (40-584): 1.27e-112: 351: 23.36
+	Dm
		422809 NOTCH_DROME (1323-2246): 9.26e-77: 288: 13.66		Q9BN17_DROME (7-543): 6.27e-42: 165: 15.39
+	Hs
		980365 NOTC2_HUMAN (1360-2243): 4.79e-72: 273: 12.64		CNTN1_HUMAN (6-604): 7.07e-43: 167: 12.82
+	Hs
		980481 NOTC2_HUMAN (1360-2243): 4.79e-72: 273: 12.64		PXDN_HUMAN (12-356): 7.19e-37: 150: 21.17
+	Hs
		433130 LAMB1_HUMAN (269-541): 1.34e-20: 103: 20.43		BCAM_HUMAN (1-610): 3.86e-97: 312: 100.00
+	Hs
		842260 LAMA4_HUMAN (901-1112): 3.71e-09: 65.4: 10.55		BCAM_HUMAN (1-610): 3.86e-97: 312: 100.00
+	Dm
		422964 NOTCH_DROME (1323-2246): 9.26e-77: 288: 13.66		Q9W4Y4_DROME (283-485): 2.52e-11: 69.3: 26.85
+	Hs
		793330 LAMA4_HUMAN (901-1112): 3.71e-09: 65.4: 10.55		MUC18_HUMAN (14-627): 1.18e-81: 271: 24.02
+	Hs
		804225 NOTC1_HUMAN (1638-2252): 1.9e-36: 155: 11.76		CNTN1_HUMAN (6-604): 7.07e-43: 167: 12.82
+	Mm
		524118 CNTP2_MOUSE (3346-3687): 3.02e-31: 137: 13.25		CNTN1_MOUSE (6-604): 1.23e-41: 164: 12.48
+	Hs
		1018311 CNTP2_HUMAN (2791-3148): 9.55e-11: 70.4: 11.33		CNTN1_HUMAN (6-604): 7.07e-43: 167: 12.82
+	Rn
		957012 CNTP1_RAT (2947-3098): 8.08e-11: 70.8: 13.92		CNTN1_RAT (6-604): 1.05e-41: 164: 12.48
+	Dm
		1213857 Q8IP51_DROME (1314-1485): 4.58e-09: 65: 13.79		Q9BN17_DROME (7-543): 6.27e-42: 165: 15.39
+	Mm
		140337 NET1_MOUSE (1404-1477): 3.15e-11: 71.5: 28.75		DSCAM_MOUSE (7-563): 1.17e-24: 112: 10.66
+	Hs
		970119 CNTP2_HUMAN (2791-3148): 9.55e-11: 70.4: 11.33		CNTN2_HUMAN (6-551): 3.54e-20: 97.5: 8.31
+	Hs
		631060 LAMA1_HUMAN (189-438): 4.74e-09: 65: 13.45		PGBM_HUMAN (234-384): 1.27e-10: 67: 15.39