HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25720964, 33658012
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006281 - DNA repair
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 709 Hs			1 707
+	Hs
		996881 SSRP1_HUMAN (1-709): 0: 805: 100.00		TBL1R_HUMAN (251-570): 8.42e-66: 228: 18.58
+	Hs
		903169 SSRP1_HUMAN (1-709): 0: 805: 100.00		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		996930 SSRP1_HUMAN (1-709): 0: 805: 100.00		NLE1_HUMAN (269-366): 5.18e-09: 61.2: 13.86
+	Hs
		1281404 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		881823 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		818834 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		567741 UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		818441 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		TBL1R_HUMAN (251-570): 8.42e-66: 228: 18.58
+	Hs
		903450 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Ce
		1089274 SOX2_CAEEL (503-706): 2.71e-35: 137: 15.46		WDR51_CAEEL (572-706): 1.26e-23: 105: 22.63
+	Hs
		817868 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		818850 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		643290 HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		449632 HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		567789 UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09