Protein: KCTD9
BTB/POZ domain-containing protein KCTD9

Gene: KCTD9
Organism: Homo sapiens
Interactions: 231
UniProt ID: Q7L273

Gene Ontology (top 5):
GO:0016567 - protein ubiquitination
GO:0035556 - intracellular signal transduction
GO:0042802 - identical protein binding
GO:0051260 - protein homooligomerization
GO:0097602 - cullin family protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1113506

CUL3
Cullin-3

13

20

Small-scale

0.982

High

1271362

KCTD9
BTB/POZ domain-containing protein KCTD9

4

17

High-throughput

0.891

High

1199990

KLH26
Kelch-like protein 26

2

4

High-throughput

0.700

High

140325

SDCB1
Syntenin-1

3

14

High-throughput

0.675

High

1093377

TRI32
E3 ubiquitin-protein ligase TRIM32

3

6

High-throughput

0.675

High

1271368

TRI42
Tripartite motif-containing protein 42

3

16

High-throughput

0.675

High

1271429

ARI1
E3 ubiquitin-protein ligase ARIH1

3

7

High-throughput

0.667

High

1271410

GORS2
Golgi reassembly-stacking protein 2

4

8

High-throughput

0.644

High

572037

TRI27
Zinc finger protein RFP

3

2

High-throughput

0.616

High

680923

PSA1
Proteasome subunit alpha type-1

3

11

High-throughput

0.616

High

933857

GEM
GTP-binding protein GEM

3

5

High-throughput

0.616

High

1165282

LONF1
LON peptidase N-terminal domain and RING finger protein 1

3

10

High-throughput

0.616

High

1214345

SYT6
Synaptotagmin-6

3

4

High-throughput

0.616

High

1218922

TASO2
Protein TASOR 2

3

4

High-throughput

0.616

High

1271415

CBX8
Chromobox protein homolog 8

3

3

High-throughput

0.616

High

1271420

GOG6A
Golgin subfamily A member 6A

3

17

High-throughput

0.607

High

1271377

LNX1
E3 ubiquitin-protein ligase LNX

2

20

High-throughput

0.606

High

1271412

UNKL
Putative E3 ubiquitin-protein ligase UNKL

2

2

High-throughput

0.606

High

64882

RCCD1
RCC1 domain-containing protein 1

3

1

High-throughput

0.604

High

164371

NRP1
Neuropilin-1

3

4

High-throughput

0.604

High

1271390

NTAQ1
Protein N-terminal glutamine amidohydrolase

3

8

High-throughput

0.593

High

934785

TERA
Transitional endoplasmic reticulum ATPase

2

3

High-throughput

0.584

High

1271406

CARD9
Caspase recruitment domain-containing protein 9

1

12

High-throughput

0.573

High

65081

GG6L9
Golgin subfamily A member 6-like protein 9

2

16

High-throughput

0.553

High

300393

KRT34
Keratin, type I cuticular Ha4

2

14

High-throughput

0.553

High

350477

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

12

High-throughput

0.553

High

664385

ZBT25
Zinc finger and BTB domain-containing protein 25

2

2

High-throughput

0.553

High

699462

PROP
Properdin

2

5

High-throughput

0.553

High

725078

HXC8
Homeobox protein Hox-C8

2

8

High-throughput

0.553

High

783717

ZNF76
Zinc finger protein 76

2

1

High-throughput

0.553

High

885309

HXA1
Homeobox protein Hox-A1

2

9

High-throughput

0.553

High

930732

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

6

High-throughput

0.553

High

1044665

ARI5A
AT-rich interactive domain-containing protein 5A

2

1

High-throughput

0.553

High

1053409

DEUP1
Deuterosome assembly protein 1

2

12

High-throughput

0.553

High

1081399

INCA1
Protein INCA1

2

1

High-throughput

0.553

High

1119744

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

2

20

High-throughput

0.553

High

1145999

K1H1
Keratin, type I cuticular Ha1

2

17

High-throughput

0.553

High

1151563

TRIP6
Thyroid receptor-interacting protein 6

2

5

High-throughput

0.553

High

1158398

CDC37
Hsp90 co-chaperone Cdc37

2

2

High-throughput

0.553

High

1187723

KR133
Keratin-associated protein 13-3

2

2

High-throughput

0.553

High

1198022

KR132
Keratin-associated protein 13-2

2

2

High-throughput

0.553

High

1224836

TENS2
Tensin-2

2

7

High-throughput

0.553

High

1250244

ATL4
ADAMTS-like protein 4

2

2

High-throughput

0.553

High

1253053

ZN620
Zinc finger protein 620

2

1

High-throughput

0.553

High

1258116

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

2

1

High-throughput

0.553

High

1271364

EPMIP
EPM2A-interacting protein 1

2

2

High-throughput

0.553

High

1271366

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

2

3

High-throughput

0.553

High

1271380

MB3L1
Methyl-CpG-binding domain protein 3-like 1

2

1

High-throughput

0.553

High

1271384

KRT35
Keratin, type I cuticular Ha5

2

15

High-throughput

0.553

High

1271393

AP4AT
AP-4 complex accessory subunit Tepsin

2

2

High-throughput

0.553

High

1271399

WDR83
WD repeat domain-containing protein 83

2

7

High-throughput

0.553

High

1271405

NIF3L
NIF3-like protein 1

2

2

High-throughput

0.553

High

1271414

KIF9
Kinesin-like protein KIF9

2

13

High-throughput

0.553

High

1271418

PICK1
PRKCA-binding protein

2

2

High-throughput

0.553

High

1271424

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

2

5

High-throughput

0.553

High

1271363

CSN6
COP9 signalosome complex subunit 6

2

4

High-throughput

0.549

High

992229

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.549

High

1063966

ECHP
Peroxisomal bifunctional enzyme

2

4

High-throughput

0.544

High

286674

STX11
Syntaxin-11

1

4

High-throughput

0.523

High

715919

AQP1
Aquaporin-1

1

2

High-throughput

0.523

High

887682

PSB2
Proteasome subunit beta type-2

1

1

High-throughput

0.523

High

1230102

K1C40
Keratin, type I cytoskeletal 40

1

13

High-throughput

0.523

High

1239703

PPR18
Phostensin

1

7

High-throughput

0.523

High

1271395

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

1

11

High-throughput

0.523

High

1271408

F124B
Protein FAM124B

1

1

High-throughput

0.523

High

1271423

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

High-throughput

0.523

High

654524

FBLN1
Fibulin-1

2

5

High-throughput

0.521

High

363480

EGFR
Epidermal growth factor receptor

2

4

Small-scale

0.516

High

1086617

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

2

High-throughput

0.494

High

50371

PXDNL
Probable oxidoreductase PXDNL

1

4

High-throughput

0.489

High

604775

HXB8
Homeobox protein Hox-B8

1

5

High-throughput

0.489

High

605008

HXB6
Homeobox protein Hox-B6

1

6

High-throughput

0.489

High

1200983

ACTBL
Beta-actin-like protein 2

1

7

High-throughput

0.489

High

1271372

F133A
Protein FAM133A

1

1

High-throughput

0.489

High

1271425

AT7L1
Ataxin-7-like protein 1

1

7

High-throughput

0.489

High

1271427

PKHA6
Pleckstrin homology domain-containing family A member 6

1

15

High-throughput

0.489

High

242097

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

647588

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

1

High-throughput

0.479

High

971699

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.479

High

1152536

ELAV1
ELAV-like protein 1

1

5

Small-scale

0.479

High

1165399

Q17RL8
HCG2004980, isoform CRA_e

1

15

High-throughput

0.470

High

1193610

Q49AR9
ANKS1A protein

1

7

High-throughput

0.470

High

1232427

Q6FHY5
MEOX2 protein

1

9

High-throughput

0.470

High

893969

MEOX2
Homeobox protein MOX-2

1

7

High-throughput

0.439

High

1131967

MVP
Major vault protein

1

1

High-throughput

0.439

High

1260557

PDZD4
PDZ domain-containing protein 4

1

20

High-throughput

0.439

High

1271383

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

11

High-throughput

0.439

High

1271419

TBA8
Tubulin alpha-8 chain

1

16

High-throughput

0.439

High

134069

IPO5
Importin-5

1

6

High-throughput

0.437

High

172992

XPO1
Exportin-1

1

13

High-throughput

0.437

High

224736

ACTN4
Alpha-actinin-4

1

16

High-throughput

0.437

High

250676

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

6

High-throughput

0.437

High

260115

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.437

High

278117

FLNB
Filamin-B

1

20

High-throughput

0.437

High

289591

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

5

High-throughput

0.437

High

358726

LDHA
L-lactate dehydrogenase A chain

1

6

High-throughput

0.437

High

402619

ALDOA
Fructose-bisphosphate aldolase A

1

2

High-throughput

0.437

High

407480

K2C1
Keratin, type II cytoskeletal 1

1

9

High-throughput

0.437

High

408089

TBB4A
Tubulin beta-4A chain

1

15

High-throughput

0.437

High

408956

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.437

High

420590

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

5

High-throughput

0.437

High

443853

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

5

High-throughput

0.437

High

445936

ENOA
Alpha-enolase

1

1

High-throughput

0.437

High

446161

PYGL
Glycogen phosphorylase, liver form

1

1

High-throughput

0.437

High

451015

LDHB
L-lactate dehydrogenase B chain

1

6

High-throughput

0.437

High

452311

PDIA1
Protein disulfide-isomerase

1

4

High-throughput

0.437

High

457517

TBB5
Tubulin beta chain

1

15

High-throughput

0.437

High

460577

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

4

High-throughput

0.437

High

461638

HS90A
Heat shock protein HSP 90-alpha

1

6

High-throughput

0.437

High

466041

ANXA6
Annexin A6

1

5

High-throughput

0.437

High

468532

HS90B
Heat shock protein HSP 90-beta

1

6

High-throughput

0.437

High

474775

VIME
Vimentin

1

17

High-throughput

0.437

High

485227

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

9

High-throughput

0.437

High

532707

CH60
60 kDa heat shock protein, mitochondrial

1

5

High-throughput

0.437

High

535231

BIP
Endoplasmic reticulum chaperone BiP

1

18

High-throughput

0.437

High

537397

HSP7C
Heat shock cognate 71 kDa protein

1

14

High-throughput

0.437

High

547635

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

1

High-throughput

0.437

High

553218

KCRB
Creatine kinase B-type

1

2

High-throughput

0.437

High

558229

XRCC6
X-ray repair cross-complementing protein 6

1

3

High-throughput

0.437

High

559398

XRCC5
X-ray repair cross-complementing protein 5

1

3

High-throughput

0.437

High

565949

EF2
Elongation factor 2

1

3

High-throughput

0.437

High

566176

K1C10
Keratin, type I cytoskeletal 10

1

16

High-throughput

0.437

High

573146

KPYM
Pyruvate kinase PKM

1

2

High-throughput

0.437

High

576789

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

3

High-throughput

0.437

High

600842

HSP76
Heat shock 70 kDa protein 6

1

14

High-throughput

0.437

High

608645

DDX5
Probable ATP-dependent RNA helicase DDX5

1

4

High-throughput

0.437

High

610738

TCPA
T-complex protein 1 subunit alpha

1

9

High-throughput

0.437

High

613380

VINC
Vinculin

1

7

High-throughput

0.437

High

616195

PGAM1
Phosphoglycerate mutase 1

1

1

High-throughput

0.437

High

620434

NUCL
Nucleolin

1

4

High-throughput

0.437

High

634502

LMNB1
Lamin-B1

1

16

High-throughput

0.437

High

637595

FLNA
Filamin-A

1

20

High-throughput

0.437

High

640935

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

3

High-throughput

0.437

High

644521

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

1

1

High-throughput

0.437

High

650825

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

9

High-throughput

0.437

High

680407

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

7

High-throughput

0.437

High

687444

PTBP1
Polypyrimidine tract-binding protein 1

1

3

High-throughput

0.437

High

691171

1433T
14-3-3 protein theta

1

20

High-throughput

0.437

High

697573

PYR1
Multifunctional protein CAD

1

7

High-throughput

0.437

High

712228

TKT
Transketolase

1

3

High-throughput

0.437

High

729324

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

10

High-throughput

0.437

High

761732

HSP74
Heat shock 70 kDa protein 4

1

17

High-throughput

0.437

High

772022

K1C9
Keratin, type I cytoskeletal 9

1

16

High-throughput

0.437

High

777504

K22E
Keratin, type II cytoskeletal 2 epidermal

1

10

High-throughput

0.437

High

828824

MDHM
Malate dehydrogenase, mitochondrial

1

5

High-throughput

0.437

High

841806

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

High-throughput

0.437

High

846358

MATR3
Matrin-3

1

4

High-throughput

0.437

High

881224

FAS
Fatty acid synthase

1

2

High-throughput

0.437

High

882001

TCPG
T-complex protein 1 subunit gamma

1

9

High-throughput

0.437

High

884533

SYAC
Alanine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.437

High

899106

TCPQ
T-complex protein 1 subunit theta

1

11

High-throughput

0.437

High

899451

TCPD
T-complex protein 1 subunit delta

1

7

High-throughput

0.437

High

910561

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

4

High-throughput

0.437

High

920836

ACLY
ATP-citrate synthase

1

3

High-throughput

0.437

High

934103

XPO2
Exportin-2

1

10

High-throughput

0.437

High

965748

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

8

High-throughput

0.437

High

967819

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

7

High-throughput

0.437

High

990405

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.437

High

996743

TBA1B
Tubulin alpha-1B chain

1

16

High-throughput

0.437

High

1007105

TCPB
T-complex protein 1 subunit beta

1

9

High-throughput

0.437

High

1008211

PRKDC
DNA-dependent protein kinase catalytic subunit

1

1

High-throughput

0.437

High

1026107

CLH1
Clathrin heavy chain 1

1

1

High-throughput

0.437

High

1027548

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

7

High-throughput

0.437

High

1028803

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

18

High-throughput

0.437

High

1038648

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

6

High-throughput

0.437

High

1051781

EF1A2
Elongation factor 1-alpha 2

1

4

High-throughput

0.437

High

1062525

DHX9
ATP-dependent RNA helicase A

1

7

High-throughput

0.437

High

1089454

ILF2
Interleukin enhancer-binding factor 2

1

2

High-throughput

0.437

High

1090447

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

2

High-throughput

0.437

High

1108583

TBB3
Tubulin beta-3 chain

1

15

High-throughput

0.437

High

1118509

TBB2A
Tubulin beta-2A chain

1

15

High-throughput

0.437

High

1123952

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

3

High-throughput

0.437

High

1134250

IMB1
Importin subunit beta-1

1

5

High-throughput

0.437

High

1147928

SF3B3
Splicing factor 3B subunit 3

1

3

High-throughput

0.437

High

1259305

TBA1A
Tubulin alpha-1A chain

1

16

High-throughput

0.437

High

1271378

IPO4
Importin-4

1

6

High-throughput

0.437

High

1271381

HS105
Heat shock protein 105 kDa

1

18

High-throughput

0.437

High

1271382

GCN1
Stalled ribosome sensor GCN1

1

6

High-throughput

0.437

High

1271386

FUBP2
Far upstream element-binding protein 2

1

8

High-throughput

0.437

High

1271397

TCPH
T-complex protein 1 subunit eta

1

9

High-throughput

0.437

High

1271398

TBA1C
Tubulin alpha-1C chain

1

18

High-throughput

0.437

High

1271401

TBB6
Tubulin beta-6 chain

1

15

High-throughput

0.437

High

1271403

TBB2B
Tubulin beta-2B chain

1

15

High-throughput

0.437

High

1271409

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.437

High

1271417

DDX21
Nucleolar RNA helicase 2

1

5

High-throughput

0.437

High

1271422

SYLC
Leucine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.437

High

1271428

TLN1
Talin-1

1

16

High-throughput

0.437

High

1271430

X5D7R7
Major vault protein

1

1

High-throughput

0.417

High

958663

CSN2
COP9 signalosome complex subunit 2

1

8

High-throughput

0.407

High

1094360

CSN1
COP9 signalosome complex subunit 1

1

7

High-throughput

0.407

High

1271385

CSN5
COP9 signalosome complex subunit 5

1

4

High-throughput

0.407

High

1271388

C102A
Coiled-coil domain-containing protein 102A

1

8

High-throughput

0.407

High

1271426

CSN3
COP9 signalosome complex subunit 3

1

6

High-throughput

0.407

High

1271376

NUP35
Nucleoporin NUP35

7

0

High-throughput

0.391

High

1211312

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

2

0

High-throughput

0.328

High

74350

ZBT42
Zinc finger and BTB domain-containing protein 42

2

0

High-throughput

0.316

High

156467

ACPM
Acyl carrier protein, mitochondrial

2

0

High-throughput

0.316

High

251924

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

2

0

High-throughput

0.316

High

1193229

SPAS1
Spermatogenesis-associated serine-rich protein 1

2

0

High-throughput

0.316

High

1200179

SMUG1
Single-strand selective monofunctional uracil DNA glycosylase

2

0

High-throughput

0.316

High

1203473

ACTMP
Actin maturation protease

2

0

High-throughput

0.316

High

1207676

MIIP
Migration and invasion-inhibitory protein

2

0

High-throughput

0.316

High

1239078

CDPF1
Cysteine-rich DPF motif domain-containing protein 1

2

0

High-throughput

0.316

High

1271365

SAXO4
Stabilizer of axonemal microtubules 4

2

0

High-throughput

0.316

High

1271367

RFX6
DNA-binding protein RFX6

2

0

High-throughput

0.316

High

1271371

SMIP4
Sperm-associated microtubule inner protein 4

2

0

High-throughput

0.316

High

1271373

BANP
Protein BANP

2

0

High-throughput

0.316

High

1271374

SMIP6
Sperm microtubule inner protein 6

2

0

High-throughput

0.316

High

1271375

SLAI1
SLAIN motif-containing protein 1

2

0

High-throughput

0.316

High

1271379

POF1B
Protein POF1B

2

0

High-throughput

0.316

High

1271389

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

1271392

SMIP9
Protein SPMIP9

2

0

High-throughput

0.316

High

1271396

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.316

High

1271402

ZN426
Zinc finger protein 426

2

0

High-throughput

0.316

High

1271404

RUSC1
AP-4 complex accessory subunit RUSC1

2

0

High-throughput

0.316

High

1271407

GO45
Golgin-45

2

0

High-throughput

0.316

High

1271411

ZN408
Zinc finger protein 408

2

0

High-throughput

0.316

High

1271416

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

0

High-throughput

0.316

High

1271421

SPG21
Maspardin

2

0

High-throughput

0.316

High

1008664

CRADD
Death domain-containing protein CRADD

1

0

High-throughput

0.299

High

1271369

PNKD
Probable thioesterase PNKD

1

0

High-throughput

0.299

High

1271387

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.299

High

1271394

ZMAT2
Zinc finger matrin-type protein 2

1

0

High-throughput

0.279

Low

1271370

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low

1241665

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.249

Low

1245960

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

0

High-throughput

0.249

Low

1248966

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1271391

SPTCS
Spatacsin

1

0

Small-scale

0.238

Low

1271400

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.232

Low

1271413

CSN7B
COP9 signalosome complex subunit 7b

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025