Interactor 1: ACS2A (Q08AH3)
Acyl-coenzyme A synthetase ACSM2A, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 2A) (Benzoate--CoA ligase) (EC 6.2.1.25) (Butyrate--CoA ligase 2A) (Butyryl-coenzyme A synthetase 2A) (Middle-chain acyl-CoA synthetase 2A)
Gene: ACSM2A

Interactor 2: ACS2B (Q68CK6)
Acyl-coenzyme A synthetase ACSM2B, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 2B) (Benzoate--CoA ligase) (EC 6.2.1.25) (Butyrate--CoA ligase 2B) (Butyryl-coenzyme A synthetase 2B) (Middle-chain acyl-CoA synthetase 2B) (Xenobiotic/medium-chain fatty acid-CoA ligase HXM-A)
Gene: ACSM2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AMP-binding~AMP-binding, AMP-binding~AMP-binding_C, AMP-binding_C~AMP-binding_C
Common GO terms GO:0004321 - fatty-acyl-CoA synthase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006633 - fatty acid biosynthetic process
and 5 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 577
Hs

1 577
+ Hs
+ Cj
+ Ec
+ Dm
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024