HitPredict

Interactor 1: VAC14 (Q08AM6)
Protein VAC14 homolog (Tax1-binding protein 2)
Gene: VAC14

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cullin~Vac14_Fab1_bd
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 782 Hs			1 768
+	Hs
		997366 VAC14_HUMAN (1-782): 0: 680: 100.00		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1042209 TNPO1_HUMAN (12-574): 6.88e-52: 197: 12.44		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		268709 SF3B1_HUMAN (8-584): 5.41e-31: 133: 9.71		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042125 IPO4_HUMAN (50-499): 4.04e-16: 84.9: 14.99		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041947 CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042184 GCN1_HUMAN (3-394): 6.91e-14: 78: 11.84		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		127264 IPO5_HUMAN (3-537): 9.42e-12: 71: 12.98		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		155572 TNPO2_HUMAN (32-373): 3.75e-11: 68.8: 11.85		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1043084 CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043440 CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		268708 SF3B1_HUMAN (8-584): 5.41e-31: 133: 9.71		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Mm
		1169688 CAND1_MOUSE (4-541): 2.78e-15: 82.6: 11.74		CUL1_MOUSE (17-768): 0: 709: 30.53
+	Hs
		1041074 CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1041383 CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1202033 CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74		CUL5_HUMAN (25-768): 0: 597: 23.77