HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: EIF3C (Q99613)
Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) (eIF3 p110)
Gene: EIF3C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	25852190, 35271311, 36736316
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 913
+	Hs
		81696 CSK21_HUMAN (1-391): 2e-136: 396: 100.00		EIFCL_HUMAN (1-913): 0: 1209: 99.13
+	Hs
		1337832 CSK23_HUMAN (1-391): 3.66e-133: 388: 98.47		EIF3C_HUMAN (1-913): 0: 1213: 100.00
+	Hs
		81725 CSK23_HUMAN (1-391): 3.66e-133: 388: 98.47		EIFCL_HUMAN (1-913): 0: 1209: 99.13
+	Hs
		668002 CDK2_HUMAN (36-330): 7.04e-122: 356: 29.74		EIF3C_HUMAN (1-913): 0: 1213: 100.00
+	Hs
		625578 CSK22_HUMAN (1-334): 1.12e-119: 352: 85.08		EIF3C_HUMAN (1-913): 0: 1213: 100.00
+	Hs
		81674 CSK22_HUMAN (1-334): 1.12e-119: 352: 85.08		EIFCL_HUMAN (1-913): 0: 1209: 99.13
+	Hs
		891760 GSK3B_HUMAN (39-389): 1.85e-112: 336: 29.12		EIF3C_HUMAN (1-913): 0: 1213: 100.00
+	At
		235525 MPK3_ARATH (22-364): 6.31e-118: 349: 24.51		EIF3C_ARATH (214-894): 0: 751: 36.69
+	Sc
		585882 CSK21_YEAST (1-329): 8.89e-113: 335: 54.32		EIF3C_YEAST (5-256): 8.66e-18: 90.6: 21.53