HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: SSXT (Q15532)
Protein SSXT (Protein SYT) (Synovial sarcoma translocated to X chromosome protein)
Gene: SS18

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	11030627
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2414 Hs			1 418
+	Hs
		257465 EP300_HUMAN (1-2414): 0: 1113: 100.00		CREST_HUMAN (1-418): 2.69e-58: 197: 55.26
+	Hs
		846760 EP300_HUMAN (1-2414): 0: 1113: 100.00		SMCA2_HUMAN (70-418): 1.67e-31: 129: 19.16
+	Hs
		846947 EP300_HUMAN (1-2414): 0: 1113: 100.00		SMCA4_HUMAN (78-418): 1.85e-20: 96.3: 16.81
+	Hs
		123923 EP300_HUMAN (1-2414): 0: 1113: 100.00		SPT5H_HUMAN (140-359): 3.33e-12: 70.5: 13.45
+	Hs
		1066967 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		SSXT_HUMAN (1-418): 1.23e-79: 253: 100.00
+	Hs
		846881 BAZ1A_HUMAN (889-1176): 3.58e-51: 202: 21.31		SMCA2_HUMAN (70-418): 1.67e-31: 129: 19.16
+	Hs
		257472 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		CREST_HUMAN (1-418): 2.69e-58: 197: 55.26
+	Hs
		846897 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		SMCA2_HUMAN (70-418): 1.67e-31: 129: 19.16
+	Hs
		847093 BRWD1_HUMAN (1007-1168): 2.52e-44: 180: 32.93		SMCA4_HUMAN (78-418): 1.85e-20: 96.3: 16.81
+	Hs
		847115 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		SMCA4_HUMAN (78-418): 1.85e-20: 96.3: 16.81
+	Hs
		631379 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		SMCA2_HUMAN (70-418): 1.67e-31: 129: 19.16
+	Hs
		846778 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		SMCA2_HUMAN (70-418): 1.67e-31: 129: 19.16
+	Hs
		1017367 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		BPTF_HUMAN (40-351): 2.2e-10: 65.1: 9.90
+	Hs
		846993 BRDT_HUMAN (1036-1159): 2.03e-33: 143: 29.84		SMCA4_HUMAN (78-418): 1.85e-20: 96.3: 16.81
+	Hs
		631380 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		SMCA4_HUMAN (78-418): 1.85e-20: 96.3: 16.81
+	Hs
		846977 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		SMCA4_HUMAN (78-418): 1.85e-20: 96.3: 16.81
+	Hs
		631413 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		BPTF_HUMAN (40-351): 2.2e-10: 65.1: 9.90
+	Hs
		1017300 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		BPTF_HUMAN (40-351): 2.2e-10: 65.1: 9.90
+	Hs
		124109 CHD7_HUMAN (69-452): 4.51e-13: 77.9: 12.02		SPT5H_HUMAN (140-359): 3.33e-12: 70.5: 13.45
+	Dm
		113976 M9PB30_DROME (5-444): 3.69e-13: 78.3: 7.05		M9PB30_DROME (66-374): 3.74e-10: 64.3: 13.10