Protein: ARHGC
Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)

Gene: ARHGC, Arhgef12
Organism: Mus musculus
Interactions: 8
UniProt ID: Q8R4H2

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0007186 - G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1274325

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

6

High-throughput

0.536

High

1283038

MYOME
Myomegalin

1

10

High-throughput

0.536

High

1233044

TEDC2
Tubulin epsilon and delta complex protein 2

1

1

High-throughput

0.479

High

1298095

RTKN
Rhotekin

1

1

Small-scale

0.479

High

1298799

PLXB1
Plexin-B1

1

16

Small-scale

0.470

High

1341605

HDAC5
Histone deacetylase 5

1

9

High-throughput

0.445

High

1190343

Q3UJF1
Histone deacetylase

1

9

High-throughput

0.437

High

1296144

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

15

High-throughput

0.437

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025