Protein: WDFY3
WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)

Gene: WDFY3
Organism: Homo sapiens
Interactions: 97
UniProt ID: Q8IZQ1

Gene Ontology (top 5):
GO:0000421 - autophagosome membrane
GO:0005545 - 1-phosphatidylinositol binding
GO:0005635 - nuclear envelope
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

152888

APAF
Apoptotic protease-activating factor 1

2

15

High-throughput

0.811

High

771213

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

1

High-throughput

0.811

High

997659

DMWD
Dystrophia myotonica WD repeat-containing protein

2

16

High-throughput

0.811

High

1078029

HERC1
Probable E3 ubiquitin-protein ligase HERC1

2

9

High-throughput

0.811

High

1123631

DCAF6
DDB1- and CUL4-associated factor 6

2

19

High-throughput

0.811

High

1218358

WDR75
WD repeat-containing protein 75

2

16

High-throughput

0.811

High

1067921

PDCD1
Programmed cell death protein 1

2

0

High-throughput

0.770

High

1036726

SQSTM
Sequestosome-1

4

3

Small-scale

0.704

High

126617

P2Y10
Putative P2Y purinoceptor 10

1

5

High-throughput

0.691

High

156872

FFAR1
Free fatty acid receptor 1

1

3

High-throughput

0.691

High

172108

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.691

High

598976

FPR1
fMet-Leu-Phe receptor

1

3

High-throughput

0.691

High

813953

GPR12
G-protein coupled receptor 12

1

1

High-throughput

0.691

High

814273

GLR
Glucagon receptor

1

1

High-throughput

0.691

High

825071

PTH2R
Parathyroid hormone 2 receptor

1

1

High-throughput

0.691

High

1031004

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

3

High-throughput

0.691

High

1224681

NEDD1
Protein NEDD1

1

15

High-throughput

0.691

High

1224712

GPR45
Probable G-protein coupled receptor 45

1

2

High-throughput

0.691

High

533151

HLAE
HLA class I histocompatibility antigen, alpha chain E

3

3

High-throughput

0.667

High

1146601

A16L1
Autophagy-related protein 16-1

1

12

Small-scale

0.665

High

203734

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

2

High-throughput

0.656

High

781083

OPRX
Nociceptin receptor

1

0

High-throughput

0.656

High

1224698

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

3

20

Small-scale

0.656

High

1224704

TRI39
E3 ubiquitin-protein ligase TRIM39

2

1

High-throughput

0.640

High

306231

GBRAP
Gamma-aminobutyric acid receptor-associated protein

2

20

Small-scale

0.634

High

400088

ICAM1
Intercellular adhesion molecule 1

2

2

High-throughput

0.628

High

1169014

DEFI8
Differentially expressed in FDCP 8 homolog

2

1

High-throughput

0.628

High

1220586

MIRO2
Mitochondrial Rho GTPase 2

2

20

High-throughput

0.628

High

1224683

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

2

1

High-throughput

0.628

High

1224685

DC2I1
Cytoplasmic dynein 2 intermediate chain 1

2

8

High-throughput

0.628

High

1224692

DDX11
ATP-dependent DNA helicase DDX11

2

2

High-throughput

0.628

High

1224687

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

6

High-throughput

0.628

High

1170759

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.618

High

1224702

ATG5
Autophagy protein 5

1

1

Small-scale

0.602

High

1224680

FLCN
Folliculin

2

0

High-throughput

0.602

High

1224709

P2RX2
P2X purinoceptor 2

2

0

High-throughput

0.602

High

1224697

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

1

20

Small-scale

0.597

High

776741

STAT3
Signal transducer and activator of transcription 3

2

1

High-throughput

0.594

High

924697

GRB2
Growth factor receptor-bound protein 2

2

8

High-throughput

0.594

High

891218

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

Small-scale

0.589

High

1152287

Q6IAW1
Gamma-aminobutyric acid receptor-associated protein

1

20

Small-scale

0.589

High

1224700

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

Small-scale

0.589

High

1224703

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

2

20

Small-scale

0.584

High

1224711

TRAF6
TNF receptor-associated factor 6

2

4

Small-scale

0.584

High

1144575

TENS2
Tensin-2

2

3

High-throughput

0.576

High

1224679

ZBT44
Zinc finger and BTB domain-containing protein 44

1

3

High-throughput

0.573

High

354503

HLAB
HLA class I histocompatibility antigen, B alpha chain

2

3

High-throughput

0.552

High

1224682

CEP76
Centrosomal protein of 76 kDa

1

0

High-throughput

0.549

High

147345

DPYL4
Dihydropyrimidinase-related protein 4

1

3

High-throughput

0.536

High

581788

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.536

High

642965

S10A4
Protein S100-A4

1

4

High-throughput

0.536

High

673285

WEE1
Wee1-like protein kinase

1

7

High-throughput

0.536

High

726305

BASI
Basigin

1

7

High-throughput

0.536

High

803634

BAG6
Large proline-rich protein BAG6

1

13

High-throughput

0.536

High

844611

RAB5C
Ras-related protein Rab-5C

1

15

High-throughput

0.536

High

1054289

NF2L1
Endoplasmic reticulum membrane sensor NFE2L1

1

7

High-throughput

0.536

High

1224691

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

10

High-throughput

0.536

High

1224706

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.536

High

1051173

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

1224689

H2B1H
Histone H2B type 1-H

1

10

High-throughput

0.515

High

1224690

OPTN
Optineurin

1

15

High-throughput

0.515

High

127645

EF2K
Eukaryotic elongation factor 2 kinase

1

0

High-throughput

0.513

High

454726

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

456899

FURIN
Furin

1

0

High-throughput

0.513

High

644600

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

0

High-throughput

0.513

High

791747

HD
Huntingtin

1

0

Small-scale

0.513

High

1099364

T132A
Transmembrane protein 132A

1

0

High-throughput

0.513

High

1224677

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

1224686

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1224694

OPALI
Opalin

1

0

High-throughput

0.513

High

1224701

F234A
Protein FAM234A

1

0

High-throughput

0.513

High

1224708

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.513

High

1224710

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.513

High

1224693

ANM6
Protein arginine N-methyltransferase 6

1

7

High-throughput

0.508

High

1224696

ANM1
Protein arginine N-methyltransferase 1

1

7

High-throughput

0.508

High

296739

ATG12
Ubiquitin-like protein ATG12

1

0

Small-scale

0.493

High

47264

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.493

High

795991

MAGA8
Melanoma-associated antigen 8

1

5

High-throughput

0.489

High

1224678

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

4

High-throughput

0.489

High

1224705

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

3

High-throughput

0.489

High

1224695

MDFI
MyoD family inhibitor

1

0

High-throughput

0.486

High

324492

BAG3
BAG family molecular chaperone regulator 3

1

5

High-throughput

0.479

High

347294

MYC
Myc proto-oncogene protein

1

11

High-throughput

0.479

High

377480

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

914203

RB11A
Ras-related protein Rab-11A

1

9

High-throughput

0.479

High

1188292

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.479

High

1224707

RTEL1
Regulator of telomere elongation helicase 1

1

2

High-throughput

0.479

High

1129933

RBG1L
Rab GTPase-activating protein 1-like

1

1

High-throughput

0.451

High

90024

D6RA96
Regulator of telomere elongation helicase 1

1

2

High-throughput

0.445

High

742390

SYUA
Alpha-synuclein

1

1

Small-scale

0.445

High

164419

TRI66
Tripartite motif-containing protein 66

1

7

High-throughput

0.437

High

1224688

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

1

High-throughput

0.437

High

269328

SG2A1
Mammaglobin-B

1

0

High-throughput

0.279

Low

677839

LCN1
Lipocalin-1

1

0

High-throughput

0.279

Low

1224684

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1224699

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.279

Low

81737

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024