Protein: RWDD3
RWD domain-containing protein 3 (RWD domain-containing sumoylation enhancer) (RSUME)

Gene: RWDD3
Organism: Homo sapiens
Interactions: 9
UniProt ID: Q9Y3V2

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0032088 - negative regulation of NF-kappaB transcription factor activity
GO:0033235 - positive regulation of protein sumoylation
GO:1902073 - positive regulation of hypoxia-inducible factor-1alpha signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

993827

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.697

High

822923

VHL
von Hippel-Lindau disease tumor suppressor

2

0

Small-scale

0.598

High

1161450

HIF1A
Hypoxia-inducible factor 1-alpha

2

0

Small-scale

0.576

High

683543

IKBA
NF-kappa-B inhibitor alpha

1

0

Small-scale

0.537

High

991465

SUMO1
Small ubiquitin-related modifier 1

1

0

Small-scale

0.537

High

223447

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

331442

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.458

High

331685

MBD4
Methyl-CpG-binding domain protein 4

1

0

Small-scale

0.458

High

49378

PLS5
Phospholipid scramblase family member 5

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025