Protein: ARRD4
Arrestin domain-containing protein 4

Gene: ARRD4, ARRDC4
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q8NCT1

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005886 - plasma membrane
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

674053

V2R
Vasopressin V2 receptor

1

16

Small-scale

0.665

High

125586

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

20

Small-scale

0.628

High

1241904

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

20

Small-scale

0.628

High

1241907

NED4L
E3 ubiquitin-protein ligase NEDD4-like

2

20

Small-scale

0.628

High

1241917

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

2

20

High-throughput

0.628

High

429087

ADRB2
Beta-2 adrenergic receptor

1

10

Small-scale

0.618

High

686010

ARRB2
Beta-arrestin-2

1

16

Small-scale

0.618

High

827246

ARRB1
Beta-arrestin-1

1

16

Small-scale

0.618

High

196327

PJA2
E3 ubiquitin-protein ligase Praja-2

1

6

High-throughput

0.536

High

207968

XPOT
Exportin-T

1

7

High-throughput

0.536

High

214621

MYO1B
Unconventional myosin-Ib

1

16

High-throughput

0.536

High

218039

PEX1
Peroxisomal ATPase PEX1

1

2

High-throughput

0.536

High

256765

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

17

High-throughput

0.536

High

280278

CBPD
Carboxypeptidase D

1

1

High-throughput

0.536

High

297381

MYO1D
Unconventional myosin-Id

1

16

High-throughput

0.536

High

301216

RHBT3
Rho-related BTB domain-containing protein 3

1

2

High-throughput

0.536

High

311589

SMC2
Structural maintenance of chromosomes protein 2

1

4

High-throughput

0.536

High

313855

SVIL
Supervillin

1

7

High-throughput

0.536

High

319928

HERC2
E3 ubiquitin-protein ligase HERC2

1

20

High-throughput

0.536

High

489990

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

4

High-throughput

0.536

High

509687

UBL4A
Ubiquitin-like protein 4A

1

20

High-throughput

0.536

High

598501

NF1
Neurofibromin

1

3

High-throughput

0.536

High

616838

JAK1
Tyrosine-protein kinase JAK1

1

9

High-throughput

0.536

High

624964

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

6

High-throughput

0.536

High

637952

PSA3
Proteasome subunit alpha type-3

1

2

High-throughput

0.536

High

653319

PYR1
Multifunctional protein CAD

1

1

High-throughput

0.536

High

656746

PSB5
Proteasome subunit beta type-5

1

7

High-throughput

0.536

High

665287

EPHA2
Ephrin type-A receptor 2

1

7

High-throughput

0.536

High

738378

BMR1A
Bone morphogenetic protein receptor type-1A

1

4

High-throughput

0.536

High

803651

BAG6
Large proline-rich protein BAG6

1

20

High-throughput

0.536

High

807778

MAP1B
Microtubule-associated protein 1B

1

14

High-throughput

0.536

High

832021

PSB3
Proteasome subunit beta type-3

1

9

High-throughput

0.536

High

832136

PSB2
Proteasome subunit beta type-2

1

8

High-throughput

0.536

High

845614

RAB9A
Ras-related protein Rab-9A

1

1

High-throughput

0.536

High

873954

S12A2
Solute carrier family 12 member 2

1

2

High-throughput

0.536

High

907102

PRS8
26S proteasome regulatory subunit 8

1

5

High-throughput

0.536

High

1031567

ATM
Serine-protein kinase ATM

1

7

High-throughput

0.536

High

1032006

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

4

High-throughput

0.536

High

1048625

DSG2
Desmoglein-2

1

2

High-throughput

0.536

High

1126014

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

6

High-throughput

0.536

High

1184838

GET4
Golgi to ER traffic protein 4 homolog

1

3

High-throughput

0.536

High

1189542

MON2
Protein MON2 homolog

1

14

High-throughput

0.536

High

1190258

LRP10
Low-density lipoprotein receptor-related protein 10

1

4

High-throughput

0.536

High

1192130

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

20

High-throughput

0.536

High

1223846

AN13A
Ankyrin repeat domain-containing protein 13A

1

2

High-throughput

0.536

High

1241900

IPO4
Importin-4

1

20

High-throughput

0.536

High

1241902

GCN1
Stalled ribosome sensor GCN1

1

14

High-throughput

0.536

High

1241905

KI16B
Kinesin-like protein KIF16B

1

3

High-throughput

0.536

High

1241906

IPO9
Importin-9

1

15

High-throughput

0.536

High

1241920

AKIB1
Ankyrin repeat and IBR domain-containing protein 1

1

6

High-throughput

0.536

High

1241921

MYO6
Unconventional myosin-VI

1

9

High-throughput

0.536

High

1241925

LRP12
Low-density lipoprotein receptor-related protein 12

1

4

High-throughput

0.536

High

165225

PLXB2
Plexin-B2

1

0

High-throughput

0.513

High

364359

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.513

High

437201

MDR1
ATP-dependent translocase ABCB1

1

0

High-throughput

0.513

High

1241901

S20A1
Sodium-dependent phosphate transporter 1

1

0

High-throughput

0.513

High

1241908

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.513

High

1241911

ABCA3
Phospholipid-transporting ATPase ABCA3

1

0

High-throughput

0.513

High

1241912

PELO
Protein pelota homolog

1

0

High-throughput

0.513

High

1241919

FANCI
Fanconi anemia group I protein

1

0

High-throughput

0.513

High

296952

LTN1
E3 ubiquitin-protein ligase listerin

1

1

High-throughput

0.489

High

819826

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

1

High-throughput

0.489

High

874138

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

4

High-throughput

0.489

High

1027727

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

4

High-throughput

0.489

High

1072695

UBE3C
Ubiquitin-protein ligase E3C

1

20

High-throughput

0.489

High

1136947

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

13

High-throughput

0.489

High

1241903

RNF31
E3 ubiquitin-protein ligase RNF31

1

7

High-throughput

0.489

High

1241909

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

4

High-throughput

0.489

High

1241910

METH
Methionine synthase

1

1

High-throughput

0.489

High

1241915

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

5

High-throughput

0.489

High

1241918

SMC4
Structural maintenance of chromosomes protein 4

1

5

High-throughput

0.489

High

1241922

MAGD2
Melanoma-associated antigen D2

1

4

High-throughput

0.489

High

1241923

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

1

High-throughput

0.489

High

926608

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

2

High-throughput

0.479

High

1117766

Q4LE69
1-phosphatidylinositol 4-kinase

1

13

High-throughput

0.479

High

1162042

TRI65
E3 ubiquitin-protein ligase TRIM65

1

4

Small-scale

0.479

High

1241916

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

4

Small-scale

0.479

High

254279

LRP4
Low-density lipoprotein receptor-related protein 4

1

3

High-throughput

0.445

High

787667

PI4KA
Phosphatidylinositol 4-kinase alpha

1

14

High-throughput

0.445

High

164429

TRI66
Tripartite motif-containing protein 66

1

7

High-throughput

0.437

High

323899

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

1241913

NFIP1
NEDD4 family-interacting protein 1

1

0

High-throughput

0.279

Low

1241914

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.279

Low

1241924

SGT1
Protein SGT1 homolog

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024