Protein: PSC
Polycomb group protein Psc (Protein posterior sex combs)

Gene: PSC
Organism: Drosophila melanogaster
Interactions: 36
UniProt ID: P35820

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006338 - chromatin remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

683669

PC
Polycomb group protein Pc

15

20

Small-scale

0.979

High

777164

RING1
E3 ubiquitin-protein ligase RING1

7

19

Small-scale

0.959

High

777153

PSC
Polycomb group protein Psc

2

19

Small-scale

0.806

High

777154

PHP
Polyhomeotic-proximal chromatin protein

15

20

Small-scale

0.759

High

777163

Q9NF31
EG:BACN25G24.3 protein

8

20

Small-scale

0.739

High

777176

Q9W215
GEO03726p1

2

20

High-throughput

0.737

High

777168

JHD1
JmjC domain-containing histone demethylation protein 1

3

19

Small-scale

0.633

High

628871

TBP
TATA-box-binding protein

3

1

Small-scale

0.625

High

777167

SCM
Polycomb protein Scm

2

20

Small-scale

0.584

High

756713

FAS2
Fasciclin-2

2

4

High-throughput

0.574

High

632449

CCNB
G2/mitotic-specific cyclin-B

1

1

Small-scale

0.561

High

777155

TAF4
Transcription initiation factor TFIID subunit 4

2

9

Small-scale

0.552

High

777171

Q9VMW2
Reticulon-like protein

2

2

High-throughput

0.533

High

777170

Q9VMV9
Reticulon-like protein

2

3

High-throughput

0.504

High

54509

TPR
Nucleoprotein TPR

1

9

Small-scale

0.479

High

68261

A8DYD3
Combgap, isoform F

1

1

Small-scale

0.479

High

121977

M9PH39
histone acetyltransferase

1

19

Small-scale

0.479

High

355888

O96689
FI11703p

1

3

Small-scale

0.479

High

567625

FSH
Homeotic protein female sterile

1

19

Small-scale

0.479

High

660378

CDK1
Cyclin-dependent kinase 1

1

5

Small-scale

0.479

High

777156

TAF5
Transcription initiation factor TFIID subunit 5

1

15

Small-scale

0.479

High

777158

TAF9
Transcription initiation factor TFIID subunit 9

1

1

Small-scale

0.479

High

777159

BRDH
Bromodomain-containing protein homolog

1

6

Small-scale

0.479

High

777160

Q7KA43
Anaphase-promoting complex subunit 11

1

1

Small-scale

0.479

High

777172

Q9VV52
LD37257p

1

19

Small-scale

0.479

High

777173

Q9VWK5
GH15225p

1

3

Small-scale

0.479

High

777157

PCL
Polycomb protein Pcl

1

15

High-throughput

0.445

High

777161

Q8IPU8
BNIP3, isoform B

1

1

High-throughput

0.445

High

777165

INO80
Chromatin-remodeling ATPase INO80

1

11

High-throughput

0.445

High

777169

SMBT
Polycomb protein Sfmbt

1

20

High-throughput

0.445

High

777174

LSD2
Lipid storage droplets surface-binding protein 2

1

1

High-throughput

0.442

High

777162

Q9I7L8
Cyclosome subunit 8

1

6

Small-scale

0.437

High

777175

Q9W1E5
Anaphase-promoting complex subunit 2

1

9

Small-scale

0.437

High

118793

M9NFI9
Neurabin-1

1

8

High-throughput

0.407

High

777166

Q9VGN4
Sarcomere length short, isoform B

1

16

High-throughput

0.407

High


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Last updated: 11Aug2025