Protein: HMGN2
Non-histone chromosomal protein HMG-17 (High mobility group nucleosome-binding domain-containing protein 2)

Gene: HMGN2
Organism: Homo sapiens
Interactions: 201
UniProt ID: P05204

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0003723 - RNA binding
GO:0005615 - extracellular space
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

398963

PARP2
Poly [ADP-ribose] polymerase 2

3

3

Small-scale

0.670

High

398810

H2A1
Histone H2A type 1

3

9

High-throughput

0.656

High

398852

H4
Histone H4

3

1

High-throughput

0.650

High

398924

H2B1H
Histone H2B type 1-H

3

11

High-throughput

0.650

High

130214

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

3

1

High-throughput

0.640

High

398860

H31
Histone H3.1

3

5

High-throughput

0.640

High

260710

H2AY
Core histone macro-H2A.1

2

13

High-throughput

0.611

High

398865

GLGB
1,4-alpha-glucan-branching enzyme

2

0

High-throughput

0.602

High

398907

ASXL1
Polycomb group protein ASXL1

2

2

High-throughput

0.601

High

398867

EP300
Histone acetyltransferase p300

2

6

Small-scale

0.595

High

398904

NAA40
N-alpha-acetyltransferase 40

2

0

High-throughput

0.585

High

398846

H2B1D
Histone H2B type 1-D

2

11

High-throughput

0.584

High

398853

H2B1C
Histone H2B type 1-C/E/F/G/I

2

11

High-throughput

0.584

High

398899

H32
Histone H3.2

2

5

High-throughput

0.584

High

398851

RL23A
Large ribosomal subunit protein uL23

2

0

High-throughput

0.576

High

398890

PDCD4
Programmed cell death protein 4

2

0

High-throughput

0.576

High

398911

KLH36
Kelch-like protein 36

2

1

High-throughput

0.574

High

398880

TERF2
Telomeric repeat-binding factor 2

1

2

High-throughput

0.568

High

396865

HMGN1
Non-histone chromosomal protein HMG-14

2

0

High-throughput

0.559

High

398831

APEX1
DNA repair nuclease/redox regulator APEX1

2

0

High-throughput

0.559

High

398815

TAU
Microtubule-associated protein tau

2

3

High-throughput

0.552

High

398826

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.547

High

328700

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.536

High

331695

NSD2
Histone-lysine N-methyltransferase NSD2

1

1

High-throughput

0.536

High

398873

MDC1
Mediator of DNA damage checkpoint protein 1

1

2

High-throughput

0.536

High

398884

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.536

High

398910

KDM8
Bifunctional peptidase and arginyl-hydroxylase JMJD5

1

1

High-throughput

0.536

High

398937

BARD1
BRCA1-associated RING domain protein 1

1

1

High-throughput

0.536

High

398953

KMT5A
N-lysine methyltransferase KMT5A

1

2

High-throughput

0.536

High

398956

BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A

1

9

High-throughput

0.536

High

398960

H2AW
Core histone macro-H2A.2

1

13

High-throughput

0.536

High

398967

BAZ1B
Tyrosine-protein kinase BAZ1B

1

10

High-throughput

0.536

High

63196

LRIQ4
Leucine-rich repeat and IQ domain-containing protein 4

1

1

High-throughput

0.515

High

300389

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

1

High-throughput

0.515

High

313725

SVIL
Supervillin

1

1

High-throughput

0.515

High

391496

H2A1B
Histone H2A type 1-B/E

1

9

High-throughput

0.515

High

398814

H14
Histone H1.4

1

3

High-throughput

0.515

High

398820

H15
Histone H1.5

1

3

High-throughput

0.515

High

398827

ICAL
Calpastatin

1

1

High-throughput

0.515

High

398833

CAPG
Macrophage-capping protein

1

1

High-throughput

0.515

High

398845

H2BFS
Histone H2B type F-S

1

11

High-throughput

0.515

High

398863

RHG04
Rho GTPase-activating protein 4

1

1

High-throughput

0.515

High

398864

H11
Histone H1.1

1

3

High-throughput

0.515

High

398872

HNF4G
Hepatocyte nuclear factor 4-gamma

1

1

High-throughput

0.515

High

398882

RHOH
Rho-related GTP-binding protein RhoH

1

1

High-throughput

0.515

High

398885

H31T
Histone H3.1t

1

5

High-throughput

0.515

High

398886

H2B2E
Histone H2B type 2-E

1

11

High-throughput

0.515

High

398891

H2B2F
Histone H2B type 2-F

1

11

High-throughput

0.515

High

398898

RHG27
Rho GTPase-activating protein 27

1

2

High-throughput

0.515

High

398913

ANR31
Ankyrin repeat domain-containing protein 31

1

2

High-throughput

0.515

High

398916

SYNE1
Nesprin-1

1

1

High-throughput

0.515

High

398918

CHD6
Chromodomain-helicase-DNA-binding protein 6

1

1

High-throughput

0.515

High

398933

H2A1H
Histone H2A type 1-H

1

9

High-throughput

0.515

High

398949

RPF2
Ribosome production factor 2 homolog

1

1

High-throughput

0.515

High

398972

SHOC2
Leucine-rich repeat protein SHOC-2

1

1

High-throughput

0.515

High

398818

PYGB
Glycogen phosphorylase, brain form

1

0

High-throughput

0.513

High

398841

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.513

High

398914

Z280C
Zinc finger protein 280C

1

0

High-throughput

0.513

High

398920

ATRIP
ATR-interacting protein

1

0

High-throughput

0.513

High

398950

PARVB
Beta-parvin

1

0

High-throughput

0.513

High

398805

HMGN2
Non-histone chromosomal protein HMG-17

1

1

Small-scale

0.501

High

398809

PARP1
Poly [ADP-ribose] polymerase 1

1

4

Small-scale

0.501

High

398861

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.501

High

398892

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.501

High

398922

KAT2B
Histone acetyltransferase KAT2B

1

6

Small-scale

0.501

High

398958

HPF1
Histone PARylation factor 1

1

1

Small-scale

0.501

High

211782

TLX3
T-cell leukemia homeobox protein 3

1

0

High-throughput

0.493

High

296597

TPPP
Tubulin polymerization-promoting protein

1

0

High-throughput

0.493

High

312884

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.493

High

398816

MLRV
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

1

0

High-throughput

0.493

High

398834

UTRN
Utrophin

1

0

High-throughput

0.493

High

398849

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.493

High

398868

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.493

High

398875

RRP5
Protein RRP5 homolog

1

0

High-throughput

0.493

High

398883

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

0

High-throughput

0.493

High

398896

TWF2
Twinfilin-2

1

0

High-throughput

0.493

High

398915

ABCF1
ATP-binding cassette sub-family F member 1

1

0

High-throughput

0.493

High

398917

NEK11
Serine/threonine-protein kinase Nek11

1

0

High-throughput

0.493

High

398926

AIDA
Axin interactor, dorsalization-associated protein

1

0

High-throughput

0.493

High

398934

ALPK3
Alpha-protein kinase 3

1

0

High-throughput

0.493

High

398940

RHXF2
Rhox homeobox family member 2

1

0

High-throughput

0.493

High

398948

WNK1
Serine/threonine-protein kinase WNK1

1

0

High-throughput

0.493

High

398954

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.493

High

398961

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.493

High

398971

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.493

High

398975

DDX52
Probable ATP-dependent RNA helicase DDX52

1

0

High-throughput

0.493

High

398812

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

398822

KPCA
Protein kinase C alpha type

1

0

Small-scale

0.480

High

398857

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.480

High

209584

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

241415

H2B1K
Histone H2B type 1-K

1

11

High-throughput

0.479

High

243788

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

308313

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

368811

ESR1
Estrogen receptor

1

1

High-throughput

0.479

High

373511

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

398806

H2B1J
Histone H2B type 1-J

1

11

High-throughput

0.479

High

398807

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

1

High-throughput

0.479

High

398811

POTEI
POTE ankyrin domain family member I

1

1

High-throughput

0.479

High

398817

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

398821

H12
Histone H1.2

1

3

High-throughput

0.479

High

398823

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

398836

PRC2A
Protein PRRC2A

1

2

High-throughput

0.479

High

398837

HSP77
Putative heat shock 70 kDa protein 7

1

2

High-throughput

0.479

High

398838

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

398839

CENPA
Histone H3-like centromeric protein A

1

5

High-throughput

0.479

High

398843

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

398844

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

2

High-throughput

0.479

High

398869

IKZF1
DNA-binding protein Ikaros

1

1

High-throughput

0.479

High

398877

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

398878

BRD3
Bromodomain-containing protein 3

1

6

High-throughput

0.479

High

398889

AMOT
Angiomotin

1

3

High-throughput

0.479

High

398895

H2A2A
Histone H2A type 2-A

1

9

High-throughput

0.479

High

398897

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

398900

H2AV
Histone H2A.V

1

11

High-throughput

0.479

High

398901

ASXL2
Putative Polycomb group protein ASXL2

1

4

High-throughput

0.479

High

398905

ZCH18
Zinc finger CCCH domain-containing protein 18

1

3

High-throughput

0.479

High

398908

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

398909

SRRM1
Serine/arginine repetitive matrix protein 1

1

2

High-throughput

0.479

High

398923

H2A1C
Histone H2A type 1-C

1

9

High-throughput

0.479

High

398925

H2B1A
Histone H2B type 1-A

1

11

High-throughput

0.479

High

398930

OPTN
Optineurin

1

2

High-throughput

0.479

High

398938

H2A1J
Histone H2A type 1-J

1

9

High-throughput

0.479

High

398939

H2B1L
Histone H2B type 1-L

1

11

High-throughput

0.479

High

398942

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

398945

ASXL3
Putative Polycomb group protein ASXL3

1

5

High-throughput

0.479

High

398962

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

398965

TBK1
Serine/threonine-protein kinase TBK1

1

1

High-throughput

0.479

High

398966

BAZ2B
Bromodomain adjacent to zinc finger domain protein 2B

1

6

High-throughput

0.479

High

398968

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.479

High

398879

RABE1
Rab GTPase-binding effector protein 1

1

1

High-throughput

0.470

High

398935

STAC3
SH3 and cysteine-rich domain-containing protein 3

1

2

High-throughput

0.470

High

398969

AT7L1
Ataxin-7-like protein 1

1

2

High-throughput

0.470

High

398976

PCLO
Protein piccolo

1

1

High-throughput

0.470

High

2129

PAL4C
Peptidyl-prolyl cis-trans isomerase A-like 4C

1

0

High-throughput

0.458

High

173793

DFB4A
Defensin beta 4A

1

0

Small-scale

0.458

High

213447

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

0

High-throughput

0.458

High

277882

PIAS1
E3 SUMO-protein ligase PIAS1

1

0

High-throughput

0.458

High

337758

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

345681

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

398808

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.458

High

398824

IBP3
Insulin-like growth factor-binding protein 3

1

0

Small-scale

0.458

High

398828

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

398829

CO5A3

1

0

High-throughput

0.458

High

398832

FEN1
Flap endonuclease 1

1

0

High-throughput

0.458

High

398842

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

398847

RHOA
Transforming protein RhoA

1

0

High-throughput

0.458

High

398850

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

398854

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

398855

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

0

High-throughput

0.458

High

398856

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.458

High

398858

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

398859

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.458

High

398862

ARF1
ADP-ribosylation factor 1

1

0

High-throughput

0.458

High

398866

PRDX1
Peroxiredoxin-1

1

0

High-throughput

0.458

High

398870

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

0

High-throughput

0.458

High

398871

CYLC2
Cylicin-2

1

0

High-throughput

0.458

High

398874

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.458

High

398881

HMGN3
High mobility group nucleosome-binding domain-containing protein 3

1

0

High-throughput

0.458

High

398894

USF3
Basic helix-loop-helix domain-containing protein USF3

1

0

High-throughput

0.458

High

398902

G2E3
G2/M phase-specific E3 ubiquitin-protein ligase

1

0

High-throughput

0.458

High

398919

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

0

High-throughput

0.458

High

398927

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

398929

CC124
Coiled-coil domain-containing protein 124

1

0

High-throughput

0.458

High

398943

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.458

High

398944

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

398946

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

398947

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.458

High

398952

RM40
Large ribosomal subunit protein mL40

1

0

High-throughput

0.458

High

398970

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.458

High

398973

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

398974

MYH15
Myosin-15

1

0

High-throughput

0.458

High

398813

ARAF
Serine/threonine-protein kinase A-Raf

1

1

High-throughput

0.437

High

398830

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

1

High-throughput

0.437

High

398876

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.437

High

398921

RND1
Rho-related GTP-binding protein Rho6

1

1

High-throughput

0.437

High

330812

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.426

High

398848

1433G
14-3-3 protein gamma

1

0

High-throughput

0.426

High

398840

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

398951

CHM1A
Charged multivesicular body protein 1a

2

0

High-throughput

0.328

High

398835

MTR1A
Melatonin receptor type 1A

1

0

High-throughput

0.282

High

232627

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.269

Low

398825

ITB6
Integrin beta-6

1

0

High-throughput

0.269

Low

398887

SPAS1
Spermatogenesis-associated serine-rich protein 1

1

0

High-throughput

0.269

Low

398888

FWCH1
FLYWCH-type zinc finger-containing protein 1

1

0

High-throughput

0.269

Low

398903

MON2
Protein MON2 homolog

1

0

High-throughput

0.269

Low

398906

CF337
Cilia- and flagella-associated protein 337

1

0

High-throughput

0.269

Low

398912

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

1

0

High-throughput

0.269

Low

398928

ASTRA
Protein Aster-A

1

0

High-throughput

0.269

Low

398932

MEG10
Multiple epidermal growth factor-like domains protein 10

1

0

High-throughput

0.269

Low

398936

KCNKG
Potassium channel subfamily K member 16

1

0

High-throughput

0.269

Low

398941

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.269

Low

398955

MXRA5
Matrix-remodeling-associated protein 5

1

0

High-throughput

0.269

Low

398959

OSER1
Oxidative stress-responsive serine-rich protein 1

1

0

High-throughput

0.269

Low

398964

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.269

Low

148280

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

260171

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

0

High-throughput

0.249

Low

398819

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.249

Low

398893

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.249

Low

398931

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

High-throughput

0.249

Low

398957

CCM2L
Cerebral cavernous malformations 2 protein-like

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024