Protein: GCH1
GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I) (Protein punch)

Gene: GCH1, Pu
Organism: Drosophila melanogaster
Interactions: 24
UniProt ID: P48596

Gene Ontology (top 5):
GO:0003934 - GTP cyclohydrolase I activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0006728 - pteridine biosynthetic process
GO:0006729 - tetrahydrobiopterin biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

874896

GCH1
GTP cyclohydrolase 1

3

7

High-throughput

0.828

High

614759

TY3H
Tyrosine 3-monooxygenase

2

0

Small-scale

0.593

High

874902

CSUP
Protein catecholamines up

1

0

Small-scale

0.529

High

94269

D5SHU5
MIP16046p

1

3

High-throughput

0.494

High

874906

Q9VMV9
Reticulon-like protein

1

1

High-throughput

0.494

High

874911

Q9VZD7
Cdc42-interacting protein 4, isoform A

1

3

High-throughput

0.494

High

118385

M9NE16
Cdc42-interacting protein 4, isoform C

1

3

High-throughput

0.481

High

874907

Q9VMW2
Reticulon-like protein

1

1

High-throughput

0.481

High

874909

MXT
Eukaryotic translation initiation factor 4E-binding protein Mextli

1

0

High-throughput

0.460

High

874903

ATLAS
Atlastin

1

0

Small-scale

0.458

High

53881

A1Z866
CAP, isoform I

1

3

High-throughput

0.451

High

74939

B3DMN9
FI09324p

1

1

High-throughput

0.451

High

874899

Q86P80
CAP, isoform K

1

2

High-throughput

0.439

High

874900

Q8MMD0
RH04491p

1

1

High-throughput

0.439

High

874912

Q9W0B3
Vacuolar protein sorting-associated protein VTA1 homolog

3

0

High-throughput

0.339

High

56432

TM208
Transmembrane protein 208

2

0

High-throughput

0.310

High

874897

Q7JRD4
Peroxisomal membrane protein PEX13

2

0

High-throughput

0.310

High

874898

Q7KNM2
Dorsal interacting protein 4

2

0

High-throughput

0.310

High

874901

FLOWR
Calcium channel flower

2

0

High-throughput

0.310

High

874904

Q9VF06
GH08991p

2

0

High-throughput

0.310

High

874905

Q9VMD2
LD47671p

2

0

High-throughput

0.310

High

874908

SFXN1
Sideroflexin-1-3

2

0

High-throughput

0.310

High

874910

Q9VVT4
IP10578p

2

0

High-throughput

0.310

High


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Last updated: 11Aug2025