Protein: Q9VYY7
Heterochromatin protein 5, isoform B

Gene: Q9VYY7, HP5
Organism: Drosophila melanogaster
Interactions: 58
UniProt ID: Q9VYY7

Gene Ontology (top 5):
GO:0000792 - heterochromatin
GO:0010369 - chromocenter

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1484547

Q9VR09
Heterochromatin protein 6

2

3

High-throughput

0.584

High

426846

HP1
Heterochromatin protein 1

2

3

High-throughput

0.562

High

614444

SGG
Protein kinase shaggy

2

1

High-throughput

0.504

High

58026

A1ZBC5
FI04829p

1

1

High-throughput

0.451

High

1302693

Q8IG84
SD21996p

1

1

High-throughput

0.451

High

1344627

Q8SYQ6
RE42228p

1

4

High-throughput

0.451

High

1488886

Q9W3J9
LP13385p

1

1

High-throughput

0.451

High

84993

B7Z126
non-specific serine/threonine protein kinase

1

0

High-throughput

0.426

High

1261187

Q7JNE1
Regulatory protein zeste

1

0

High-throughput

0.426

High

559091

PP12
Serine/threonine-protein phosphatase alpha-2 isoform

1

1

High-throughput

0.417

High

1203019

Q5BI51
LP02810p

1

1

High-throughput

0.417

High

1467615

ZIPIC
Zinc finger protein ZIPIC

1

1

High-throughput

0.417

High

1467898

Q9VAF3
Uncharacterized protein, isoform A

1

2

High-throughput

0.417

High

1476358

Q9VHM4
Ranshi

1

4

High-throughput

0.417

High

1478439

Q9VJE7
AT25465p

1

1

High-throughput

0.417

High

1484512

Q9VQY8
Vacuolar protein sorting-associated protein 53 homolog

1

1

High-throughput

0.417

High

1486407

SMD1
Probable small nuclear ribonucleoprotein Sm D1

1

1

High-throughput

0.417

High

1487804

Q9VWE4
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

1

High-throughput

0.417

High

608053

TTKB
Protein tramtrack, beta isoform

1

2

High-throughput

0.407

High

1261906

Q7JRJ9
Inner centromere protein, isoform A

1

1

High-throughput

0.407

High

1264387

Q7K0T7
LD33470p

1

2

High-throughput

0.407

High

1285485

MMD4
Modifier of mdg4

1

2

High-throughput

0.407

High

1304069

SLE
Protein slender lobes

1

1

High-throughput

0.407

High

1467602

Q9VAA9
JIL-1 anchoring and stabilizing protein, isoform A

1

1

High-throughput

0.407

High

1475056

Q9VGQ1
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.407

High

1477967

Q9VJ12
Acinus, isoform A

1

1

High-throughput

0.407

High

1488492

Q9VXY3
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

1

1

High-throughput

0.407

High

122184

M9PHX2
Visgun, isoform E

1

0

High-throughput

0.253

Low

1440559

PDE9A
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

1

0

High-throughput

0.238

Low

54190

A1Z898
Chromatin assembly factor 1, p105 subunit

1

0

High-throughput

0.232

Low

84825

B7Z0I8
Titin

1

0

High-throughput

0.232

Low

118112

M9MSJ7
Uncharacterized protein, isoform C

1

0

High-throughput

0.232

Low

669792

RCC1
Regulator of chromosome condensation

1

0

High-throughput

0.232

Low

773398

RFC1
Replication factor C subunit 1

1

0

High-throughput

0.232

Low

1050949

SSRP1
FACT complex subunit Ssrp1

1

0

High-throughput

0.232

Low

1173980

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

0

High-throughput

0.232

Low

1236963

Q6NP69
GST-containing FLYWCH zinc-finger protein

1

0

High-throughput

0.232

Low

1257872

BOCKS
LEM domain-containing protein Bocksbeutel

1

0

High-throughput

0.232

Low

1268876

NHK1
Nucleosomal histone kinase 1

1

0

High-throughput

0.232

Low

1306370

SPT16
FACT complex subunit spt16

1

0

High-throughput

0.232

Low

1306456

INDRA
Zinc finger protein indra

1

0

High-throughput

0.232

Low

1345058

GLYR1
Cytokine-like nuclear factor N-PAC

1

0

High-throughput

0.232

Low

1345408

CHM4
Charged multivesicular body protein 4

1

0

High-throughput

0.232

Low

1374879

DYLT
Dynein light chain Tctex-type

1

0

High-throughput

0.232

Low

1409475

Q9BMQ0
Toutatis

1

0

High-throughput

0.232

Low

1463946

RUVB2
RuvB-like helicase 2

1

0

High-throughput

0.232

Low

1471739

Q9VDL2
LD40493p

1

0

High-throughput

0.232

Low

1476120

Q9VHC0
LD23870p

1

0

High-throughput

0.232

Low

1476186

Q9VHG5
Insulator binding factor 1, isoform A

1

0

High-throughput

0.232

Low

1478250

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

0

High-throughput

0.232

Low

1478840

LOQS
Protein Loquacious

1

0

High-throughput

0.232

Low

1479632

MPND
MPN domain-containing protein CG4751

1

0

High-throughput

0.232

Low

1484229

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.232

Low

1488103

Q9VX35
LD36501p

1

0

High-throughput

0.232

Low

1488499

LSD2
Lipid storage droplets surface-binding protein 2

1

0

High-throughput

0.232

Low

1488884

Q9W140
Regulatory protein zeste

1

0

High-throughput

0.232

Low

1488885

Q9W3D1
Chromatin assembly factor 1, p180 subunit

1

0

High-throughput

0.232

Low

1488887

4EBP
Eukaryotic translation initiation factor 4E-binding protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025