Protein: PC
Polycomb group protein Pc (Protein polycomb)

Gene: PC
Organism: Drosophila melanogaster
Interactions: 49
UniProt ID: P26017

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

683669

PSC
Polycomb group protein Psc

15

20

Small-scale

0.979

High

683689

RING1
E3 ubiquitin-protein ligase RING1

10

20

Small-scale

0.966

High

381693

H3
Histone H3

6

20

Small-scale

0.935

High

669795

SUZ2
Protein suppressor 2 of zeste

3

20

Small-scale

0.827

High

683670

PHP
Polyhomeotic-proximal chromatin protein

18

20

Small-scale

0.761

High

683687

Q9NF31
EG:BACN25G24.3 protein

11

20

Small-scale

0.751

High

683685

HDAC1
Histone deacetylase HDAC1

3

14

Small-scale

0.656

High

628870

TBP
TATA-box-binding protein

3

2

Small-scale

0.625

High

380875

H2B
Histone H2B

1

20

Small-scale

0.618

High

426627

HP1
Heterochromatin protein 1

1

20

Small-scale

0.618

High

477711

H2AV
Histone H2A.v

1

20

Small-scale

0.618

High

633969

TRX
Histone-lysine N-methyltransferase trithorax

1

20

Small-scale

0.618

High

683676

H2A
Histone H2A

1

20

Small-scale

0.618

High

567624

FSH
Homeotic protein female sterile

2

20

Small-scale

0.584

High

683682

BRDH
Bromodomain-containing protein homolog

2

14

Small-scale

0.584

High

683683

PHO
Polycomb protein PHO

2

20

Small-scale

0.584

High

683694

SCM
Polycomb protein Scm

2

20

Small-scale

0.584

High

683695

SMBT
Polycomb protein Sfmbt

2

20

Small-scale

0.584

High

683699

Q9W1A9
histone acetyltransferase

2

19

Small-scale

0.584

High

683697

Q9VV77
Polycomb group RING finger protein 3

1

20

High-throughput

0.575

High

121974

M9PH39
histone acetyltransferase

1

20

Small-scale

0.561

High

683673

TAF4
Transcription initiation factor TFIID subunit 4

2

10

Small-scale

0.552

High

683679

ESC
Polycomb protein esc

2

18

Small-scale

0.552

High

54194

A1Z8A4
Pipsqueak, isoform A

1

20

Small-scale

0.479

High

68260

A8DYD3
Combgap, isoform F

1

20

Small-scale

0.479

High

355887

O96689
FI11703p

1

1

Small-scale

0.479

High

402259

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

5

Small-scale

0.479

High

431629

ADF1
Transcription factor Adf-1

1

6

Small-scale

0.479

High

559022

PP12
Serine/threonine-protein phosphatase alpha-2 isoform

1

2

Small-scale

0.479

High

559124

ELF1
Protein grainyhead

1

2

Small-scale

0.479

High

683668

TF2B
Transcription initiation factor IIB

1

1

Small-scale

0.479

High

683672

EZ
Histone-lysine N-methyltransferase E(z)

1

20

Small-scale

0.479

High

683674

TAF5
Transcription initiation factor TFIID subunit 5

1

11

Small-scale

0.479

High

683675

H4
Histone H4

1

15

Small-scale

0.479

High

683677

BRC1
Broad-complex core protein isoforms 1/2/3/4/5

1

20

Small-scale

0.479

High

683678

GAGA
Transcription activator GAGA

1

20

Small-scale

0.479

High

683681

TAF9
Transcription initiation factor TFIID subunit 9

1

1

Small-scale

0.479

High

683684

MIDN
Midnolin homolog

1

2

Small-scale

0.479

High

683686

EBI
F-box-like/WD repeat-containing protein ebi

1

11

Small-scale

0.479

High

683690

Q9VCD8
Structural maintenance of chromosomes protein

1

4

Small-scale

0.479

High

683692

KMT5A
Histone-lysine N-methyltransferase Set8

1

20

Small-scale

0.479

High

683693

RDX
Protein roadkill

1

6

Small-scale

0.479

High

683698

Q9VXE9
Structural maintenance of chromosomes protein

1

4

Small-scale

0.479

High

683700

NU931
Nuclear pore complex protein Nup93-1

1

1

Small-scale

0.479

High

683671

CORTO
Centrosomal and chromosomal factor

1

0

Small-scale

0.458

High

683696

EAF6
Chromatin modification-related protein MEAF6

1

0

Small-scale

0.458

High

683680

PCL
Polycomb protein Pcl

1

19

High-throughput

0.445

High

683688

WARTS
Serine/threonine-protein kinase Warts

1

2

Small-scale

0.437

High

683691

Q9VFE7
Nuclear pore protein

1

1

Small-scale

0.437

High


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Last updated: 11Aug2025