Protein: HARS1
Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)

Gene: HARS1
Organism: Homo sapiens
Interactions: 44
UniProt ID: P12081

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004821 - histidine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

517879

SYHM
Histidine--tRNA ligase, mitochondrial

4

13

High-throughput

0.895

High

517866

HARS1
Histidine--tRNA ligase, cytoplasmic

1

13

Small-scale

0.692

High

517895

SGCZ
Zeta-sarcoglycan

3

1

High-throughput

0.656

High

517896

TNIK
TRAF2 and NCK-interacting protein kinase

2

3

High-throughput

0.590

High

517889

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

3

High-throughput

0.571

High

517871

EF1G
Elongation factor 1-gamma

1

1

Small-scale

0.561

High

517881

TTC3
E3 ubiquitin-protein ligase TTC3

1

6

High-throughput

0.541

High

517870

EF1B
Elongation factor 1-beta

1

0

Small-scale

0.537

High

56501

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

0

High-throughput

0.513

High

517869

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

0

High-throughput

0.513

High

174584

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

5

High-throughput

0.501

High

226377

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

345799

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

373606

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

384177

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

503334

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

517868

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

517873

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

517876

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

517880

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

517883

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

517885

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

High-throughput

0.479

High

517886

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

517890

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

517892

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

517893

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.479

High

517894

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

517897

TRAF6
TNF receptor-associated factor 6

1

3

High-throughput

0.479

High

517882

PRS8
26S proteasome regulatory subunit 8

1

0

High-throughput

0.460

High

148335

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

517875

MSX2
Homeobox protein MSX-2

1

0

High-throughput

0.458

High

517877

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

517891

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

496182

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High

517887

DAG1
Dystroglycan 1

1

1

Small-scale

0.445

High

517888

NEDD8
NEDD8

1

1

Small-scale

0.445

High

329294

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

517867

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

517872

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

517874

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

517884

Q08AT0
SGCZ protein

1

1

High-throughput

0.407

High

517878

MTR1B
Melatonin receptor type 1B

1

0

High-throughput

0.265

Low

351914

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024