Protein: Q9VCC9
LD23779p (Tsc1)

Gene: Q9VCC9, Tsc1
Organism: Drosophila melanogaster
Interactions: 159
UniProt ID: Q9VCC9

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0007165 - signal transduction
GO:0007424 - open tracheal system development
GO:0007584 - response to nutrient
GO:0008285 - negative regulation of cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

120351

M9PD17
Gigas, isoform B

4

13

Small-scale

0.873

High

709561

1433Z
14-3-3 protein zeta

2

20

High-throughput

0.611

High

1019899

1433E
14-3-3 protein epsilon

2

16

High-throughput

0.611

High

1470246

Q9VW83
Gigas, isoform A

1

13

High-throughput

0.575

High

1172176

DYL1
Dynein light chain 1, cytoplasmic

2

8

High-throughput

0.571

High

263490

O61380
Eukaryotic translation initiation factor 4G1, isoform A

2

5

High-throughput

0.548

High

618785

DDX17
ATP-dependent RNA helicase p62

2

6

High-throughput

0.548

High

1470204

Q9VCC4
TBC1 domain family member 7

1

2

High-throughput

0.536

High

1470234

RHEB
GTP-binding protein Rheb homolog

1

18

High-throughput

0.536

High

909947

SRP
Box A-binding factor

1

1

High-throughput

0.508

High

1464984

RYK2
Tyrosine-protein kinase Dnt

1

20

High-throughput

0.508

High

57057

A1ZAN6
Rho guanine nucleotide exchange factor 2, isoform D

1

15

High-throughput

0.479

High

561590

SPTCA
Spectrin alpha chain

1

20

High-throughput

0.479

High

666621

MLE
Dosage compensation regulator mle

1

8

High-throughput

0.479

High

674042

BRM
ATP-dependent helicase brm

1

18

High-throughput

0.479

High

715371

BIP
Endoplasmic reticulum chaperone BiP

1

15

High-throughput

0.479

High

1064232

SQD
RNA-binding protein squid

1

10

High-throughput

0.479

High

1303510

Q8IN05
Liquid facets-Related, isoform D

1

7

High-throughput

0.479

High

1321622

GNL3
Guanine nucleotide-binding protein-like 3 homolog

1

2

High-throughput

0.479

High

1346127

PUF68
Poly(U)-binding-splicing factor hfp

1

7

High-throughput

0.479

High

1374475

HDAC1
Histone deacetylase HDAC1

1

20

High-throughput

0.479

High

1377293

Q95RE4
LD37574p

1

1

High-throughput

0.479

High

1445322

DOM
Helicase domino

1

20

High-throughput

0.479

High

1470223

RAGP1
Ran GTPase-activating protein

1

4

High-throughput

0.479

High

1470226

TOR
Serine/threonine-protein kinase mTor

1

9

Small-scale

0.479

High

1470237

Q9VPL9
FI24801p1

1

17

High-throughput

0.479

High

1470239

Q9VR61
non-specific serine/threonine protein kinase

1

19

High-throughput

0.479

High

1469432

NPL4
Nuclear protein localization protein 4 homolog

1

1

High-throughput

0.464

High

1470261

Q9W3A1
Uncharacterized protein, isoform A

1

18

High-throughput

0.464

High

1470262

USO1
General vesicular transport factor p115

1

1

High-throughput

0.464

High

732231

RL7
Large ribosomal subunit protein uL30

1

2

High-throughput

0.439

High

1470228

Q9VKI8
GH03305p

1

5

High-throughput

0.439

High

52480

A1Z6Z7
Uncharacterized protein, isoform A

1

5

High-throughput

0.437

High

54224

PWP1
Periodic tryptophan protein 1 homolog

1

15

High-throughput

0.437

High

56735

A1ZAH8
40S ribosomal protein S15

1

1

High-throughput

0.437

High

56991

A1ZAK9
P-element somatic inhibitor, isoform A

1

11

High-throughput

0.437

High

57171

PTRO
Patronin

1

3

High-throughput

0.437

High

57212

DCR2
Endoribonuclease Dcr-2

1

5

High-throughput

0.437

High

57292

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.437

High

58583

A1ZBW6
Uncharacterized protein, isoform A

1

12

High-throughput

0.437

High

94917

E1JGL8
Uncharacterized protein, isoform C

1

13

High-throughput

0.437

High

98451

F0JAG2
MIP27703p

1

3

High-throughput

0.437

High

118610

M9NF08
ZAP3, isoform D

1

1

High-throughput

0.437

High

118627

M9NF14
IGF-II mRNA-binding protein, isoform L

1

10

High-throughput

0.437

High

120883

M9PEE1
Smallminded, isoform H

1

11

High-throughput

0.437

High

121930

M9PGZ8
Smrter, isoform G

1

18

High-throughput

0.437

High

145784

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

19

High-throughput

0.437

High

232151

O44434
QKR58E-3

1

8

High-throughput

0.437

High

235137

O46307
EG:8D8.4 protein

1

1

High-throughput

0.437

High

263399

PENG
Protein penguin

1

1

High-throughput

0.437

High

264639

COPB2
Coatomer subunit beta'

1

14

High-throughput

0.437

High

356837

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

18

High-throughput

0.437

High

429103

RLA2
Large ribosomal subunit protein P2

1

1

High-throughput

0.437

High

471495

RLA1
Large ribosomal subunit protein P1

1

1

High-throughput

0.437

High

554096

TCPA
T-complex protein 1 subunit alpha

1

9

High-throughput

0.437

High

607500

RS17
Small ribosomal subunit protein eS17

1

1

High-throughput

0.437

High

710946

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.437

High

760398

TTF2
Transcription termination factor 2

1

8

High-throughput

0.437

High

832190

RL18A
Large ribosomal subunit protein eL20

1

1

High-throughput

0.437

High

870612

RL23
Large ribosomal subunit protein uL14

1

1

High-throughput

0.437

High

898297

RL9
Large ribosomal subunit protein uL6

1

1

High-throughput

0.437

High

939573

RS9
Small ribosomal subunit protein uS4

1

2

High-throughput

0.437

High

1019462

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

4

High-throughput

0.437

High

1042430

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.437

High

1044930

NONA
Protein no-on-transient A

1

11

High-throughput

0.437

High

1069306

Q0E8J0
MOG interacting and ectopic P-granules protein 1

1

5

High-throughput

0.437

High

1069820

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

11

High-throughput

0.437

High

1070024

RS11
Small ribosomal subunit protein uS17

1

2

High-throughput

0.437

High

1173942

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

20

High-throughput

0.437

High

1175606

CAF1
Chromatin assembly factor 1 p55 subunit

1

19

High-throughput

0.437

High

1193032

Q494K2
Chromosome transmission fidelity 4

1

20

High-throughput

0.437

High

1207937

Q5KTT4
Eukaryotic translation initiation factor 4 gamma 2

1

7

High-throughput

0.437

High

1263891

Q7K012
Brahma associated protein 55kD

1

20

High-throughput

0.437

High

1264468

BOP1
Ribosome biogenesis protein BOP1 homolog

1

20

High-throughput

0.437

High

1267359

Q7KLW9
Pre-mRNA-processing factor 19

1

19

High-throughput

0.437

High

1268178

Q7KN94
Electron transfer flavoprotein subunit alpha

1

1

High-throughput

0.437

High

1269427

Q7KTV5
Nopp140, isoform B

1

17

High-throughput

0.437

High

1269943

Q7KV70
Karst, isoform C

1

20

High-throughput

0.437

High

1269970

Q7KV89
Mitogen-activated protein kinase kinase kinase kinase

1

20

High-throughput

0.437

High

1270163

Q7KVW1
RE73736p

1

5

High-throughput

0.437

High

1302228

Q8I937
Ribosome biogenesis regulatory protein

1

1

High-throughput

0.437

High

1304048

SLE
Protein slender lobes

1

12

High-throughput

0.437

High

1304412

Q8IP62
Mitochondrial ribosomal protein S23

1

3

High-throughput

0.437

High

1306046

CLSPN
Claspin

1

13

High-throughput

0.437

High

1344121

Q8SY39
ATP-dependent RNA helicase DDX54

1

9

High-throughput

0.437

High

1344557

Q8SYL1
Glutamate-rich WD repeat-containing protein 1

1

18

High-throughput

0.437

High

1345662

RS23
Small ribosomal subunit protein uS12

1

1

High-throughput

0.437

High

1439916

CAPR1
Caprin homolog

1

20

High-throughput

0.437

High

1458170

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

7

High-throughput

0.437

High

1463427

RL8
Large ribosomal subunit protein uL2

1

2

High-throughput

0.437

High

1464989

Q9V426
LD07162p

1

5

High-throughput

0.437

High

1466570

EPB41
Protein 4.1 homolog

1

20

High-throughput

0.437

High

1467529

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.437

High

1468519

LARP
La-related protein 1

1

12

High-throughput

0.437

High

1468857

Q9VB22
LD33695p

1

6

High-throughput

0.437

High

1469788

Q9VBX3
Vig2, isoform B

1

5

High-throughput

0.437

High

1469805

Q9VBY2
FI08810p

1

4

High-throughput

0.437

High

1470147

ANKHM
Ankyrin repeat and KH domain-containing protein mask

1

9

High-throughput

0.437

High

1470213

RPF2
Ribosome production factor 2 homolog

1

1

High-throughput

0.437

High

1470214

Q9VEH0
Aluminum tubes, isoform A

1

20

High-throughput

0.437

High

1470215

RRP15
RRP15-like protein

1

1

High-throughput

0.437

High

1470216

Q9VFT4
AT27578p

1

9

High-throughput

0.437

High

1470217

Q9VG05
Uncharacterized protein, isoform H

1

8

High-throughput

0.437

High

1470218

MBDR2
Protein MBD-R2

1

4

High-throughput

0.437

High

1470219

IPO9
Importin-9

1

7

High-throughput

0.437

High

1470220

Y6693
J domain-containing protein CG6693

1

12

High-throughput

0.437

High

1470221

Q9VHC7
FI21236p1

1

6

High-throughput

0.437

High

1470222

NOC3L
Nucleolar complex protein 3

1

3

High-throughput

0.437

High

1470224

Q9VJ86
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.437

High

1470225

RRP1L
Ribosomal RNA processing protein 1 homolog

1

8

High-throughput

0.437

High

1470227

Q9VK59
LD23647p

1

11

High-throughput

0.437

High

1470229

Q9VL71
LD29830p

1

5

High-throughput

0.437

High

1470230

Q9VLC5
aldehyde dehydrogenase

1

1

High-throughput

0.437

High

1470231

Y3096
Ribosomal L1 domain-containing protein CG13096

1

10

High-throughput

0.437

High

1470232

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

20

High-throughput

0.437

High

1470233

Q9VNC1
Large ribosomal subunit protein mL44

1

1

High-throughput

0.437

High

1470235

RL13A
Large ribosomal subunit protein uL13

1

2

High-throughput

0.437

High

1470236

Q9VP57
LD15904p

1

3

High-throughput

0.437

High

1470238

Q9VQK7
LD45152p

1

1

High-throughput

0.437

High

1470240

Q9VTC1
ATP-dependent RNA helicase DDX42

1

8

High-throughput

0.437

High

1470241

KRI1
Protein KRI1 homolog

1

7

High-throughput

0.437

High

1470243

AGO2
Protein argonaute-2

1

4

High-throughput

0.437

High

1470244

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

9

High-throughput

0.437

High

1470247

Q9VXK5
Putative rRNA methyltransferase

1

7

High-throughput

0.437

High

1470248

Q9VXQ0
Large ribosomal subunit protein uL3m

1

3

High-throughput

0.437

High

1470249

RRP12
RRP12-like protein

1

1

High-throughput

0.437

High

1470250

Q9VYQ9
Pleiotropic regulator 1

1

16

High-throughput

0.437

High

1470252

BRX1
Ribosome biogenesis protein BRX1 homolog

1

6

High-throughput

0.437

High

1470253

Q9W0R0
Cell division cycle 5, isoform A

1

5

High-throughput

0.437

High

1470254

NU301
Nucleosome-remodeling factor subunit NURF301

1

20

High-throughput

0.437

High

1470255

Q9W1G7
LD21576p

1

4

High-throughput

0.437

High

1470256

RTF1
RNA polymerase-associated protein Rtf1

1

2

High-throughput

0.437

High

1470258

DCAF1
Protein mahjong

1

1

High-throughput

0.437

High

1470260

LST8
Protein LST8 homolog

1

17

High-throughput

0.437

High

1470263

Q9W425
Rabconnectin-3A

1

18

High-throughput

0.437

High

1470265

Q9W4M7
Twenty-four, isoform B

1

10

High-throughput

0.437

High

1470266

NSUN2
tRNA

1

2

High-throughput

0.437

High

1470267

EI3G1
Eukaryotic translation initiation factor 3 subunit G-1

1

8

High-throughput

0.437

High

1070952

Q0KI87
Nuak family kinase, isoform A

1

20

High-throughput

0.407

High

1470212

INO80
Chromatin-remodeling ATPase INO80

1

15

High-throughput

0.407

High

874691

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

High-throughput

0.265

Low

1470242

Q9VUA5
LD42058p

1

0

High-throughput

0.251

Low

55296

PTCD3
Small ribosomal subunit protein mS39

1

0

High-throughput

0.249

Low

95047

E1JH23
Oxysterol-binding protein

1

0

High-throughput

0.249

Low

836569

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.249

Low

1265000

ARC1
Activity-regulated cytoskeleton associated protein 1

1

0

High-throughput

0.249

Low

1269355

Q7KTL4
Septin interacting protein 2, isoform C

1

0

High-throughput

0.249

Low

1285809

Q86BS3
Chromator, isoform A

1

0

High-throughput

0.249

Low

1345583

Q8T3H9
AT04280p

1

0

High-throughput

0.249

Low

1467283

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

High-throughput

0.249

Low

1469844

Q9VC08
LD43724p

1

0

High-throughput

0.249

Low

1470211

EI3D1
Eukaryotic translation initiation factor 3 subunit D-1

1

0

High-throughput

0.249

Low

1470245

Q9VUX1
Small ribosomal subunit protein mS31

1

0

High-throughput

0.249

Low

1470251

Q9VZC8
GEO12024p1

1

0

High-throughput

0.249

Low

1470257

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.249

Low

1470259

Q9W2Y4
RNA-binding protein NOB1

1

0

High-throughput

0.249

Low

1470264

Q9W4C1
IP13321p

1

0

High-throughput

0.249

Low

1470268

X2JDG0
Caper, isoform H

1

0

High-throughput

0.249

Low

1202399

7B2
Neuroendocrine protein 7B2

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025