Protein: CTNB1
Catenin beta-1 (Beta-catenin)

Gene: CTNB1, Ctnnb1
Organism: Mus musculus
Interactions: 118
UniProt ID: Q02248

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0000209 - protein polyubiquitination
GO:0000578 - embryonic axis specification
GO:0000791 - euchromatin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

454955

CADH1
Cadherin-1

16

20

Small-scale

0.982

High

193181

AXIN1
Axin-1

8

7

Small-scale

0.958

High

653458

LEF1
Lymphoid enhancer-binding factor 1

6

20

Small-scale

0.940

High

970151

Q8BNP7
Adenomatous polyposis coli N-terminal dimerisation domain-containing protein

5

9

Small-scale

0.919

High

970158

TF7L2
Transcription factor 7-like 2

5

20

Small-scale

0.902

High

970165

CNBP1
Beta-catenin-interacting protein 1

2

2

Small-scale

0.828

High

544708

CADH2
Cadherin-2

3

20

Small-scale

0.827

High

291896

AXIN2
Axin-2

2

7

Small-scale

0.793

High

703485

STF1
Steroidogenic factor 1

2

8

Small-scale

0.776

High

970121

CTNB1
Catenin beta-1

2

12

Small-scale

0.757

High

677637

CTND1
Catenin delta-1

2

16

Small-scale

0.754

High

877529

CADH5
Cadherin-5

2

20

Small-scale

0.754

High

640689

CTNA1
Catenin alpha-1

5

12

Small-scale

0.705

High

970172

GSK3B
Glycogen synthase kinase-3 beta

4

10

Small-scale

0.683

High

970136

ITF2
Transcription factor 4

4

3

Small-scale

0.680

High

970166

KC1E
Casein kinase I isoform epsilon

3

7

Small-scale

0.670

High

926360

THA
Thyroid hormone receptor alpha

1

16

Small-scale

0.665

High

101436

F8VPR5
histone acetyltransferase

3

20

Small-scale

0.661

High

675603

HMGB2
High mobility group protein B2

1

14

Small-scale

0.647

High

834385

PSN1
Presenilin-1

3

2

Small-scale

0.640

High

56812

A2A5J5
Neuralized E3 ubiquitin protein ligase 2

2

1

Small-scale

0.624

High

509314

RARA
Retinoic acid receptor alpha

1

19

Small-scale

0.618

High

580479

ANDR
Androgen receptor

1

20

Small-scale

0.618

High

587100

ESR1
Estrogen receptor

1

20

Small-scale

0.618

High

776233

SOX6
Transcription factor SOX-6

1

20

Small-scale

0.618

High

818698

SOX2
Transcription factor SOX-2

1

19

Small-scale

0.618

High

970139

SOX17
Transcription factor SOX-17

1

19

Small-scale

0.618

High

970176

TF7L1
Transcription factor 7-like 1

1

20

Small-scale

0.618

High

970122

TF65
Transcription factor p65

2

10

Small-scale

0.611

High

970142

DLG4
Disks large homolog 4

2

5

High-throughput

0.611

High

970162

DLGP1
Disks large-associated protein 1

2

1

High-throughput

0.611

High

949268

TNIK
Traf2 and NCK-interacting protein kinase

2

4

Small-scale

0.601

High

970163

TX1B3
Tax1-binding protein 3

1

11

Small-scale

0.586

High

102997

G3X9H5
Huntingtin

2

3

Small-scale

0.584

High

590304

PO5F1
POU domain, class 5, transcription factor 1

2

8

Small-scale

0.584

High

799597

CBP
Histone lysine acetyltransferase CREBBP

2

20

Small-scale

0.584

High

970137

KLF4
Krueppel-like factor 4

2

5

Small-scale

0.584

High

956508

PROP1
Homeobox protein prophet of Pit-1

1

3

Small-scale

0.578

High

643083

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

10

Small-scale

0.576

High

925786

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.575

High

970150

RHG32
Rho GTPase-activating protein 32

1

5

Small-scale

0.573

High

660881

PTPRM
Receptor-type tyrosine-protein phosphatase mu

1

20

Small-scale

0.536

High

723573

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

4

High-throughput

0.536

High

970123

PECA1
Platelet endothelial cell adhesion molecule

1

6

Small-scale

0.536

High

970134

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

7

Small-scale

0.536

High

970135

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

3

High-throughput

0.536

High

970140

FXR1
RNA-binding protein FXR1

1

5

High-throughput

0.536

High

970148

MYOME
Myomegalin

1

5

High-throughput

0.536

High

970153

PEX5R
PEX5-related protein

1

5

High-throughput

0.536

High

970164

TSC1
Hamartin

1

11

High-throughput

0.536

High

250819

FHL2
Four and a half LIM domains protein 2

1

5

Small-scale

0.506

High

970124

MITF
Microphthalmia-associated transcription factor

1

2

Small-scale

0.506

High

623696

PAX3
Paired box protein Pax-3

1

1

Small-scale

0.501

High

936911

CASP3
Caspase-3

1

2

Small-scale

0.501

High

970173

CARM1
Histone-arginine methyltransferase CARM1

1

2

Small-scale

0.501

High

222400

AF10
Protein AF-10

1

4

Small-scale

0.500

High

970161

PPAC
Low molecular weight phosphotyrosine protein phosphatase

1

0

Small-scale

0.493

High

724593

IRS1
Insulin receptor substrate 1

1

4

Small-scale

0.484

High

56908

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

19

Small-scale

0.479

High

70913

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.479

High

92959

PRRT2
Proline-rich transmembrane protein 2

1

2

High-throughput

0.479

High

99964

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

6

High-throughput

0.479

High

139382

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

High-throughput

0.479

High

192947

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

1

High-throughput

0.479

High

250615

LNX1
E3 ubiquitin-protein ligase LNX

1

19

High-throughput

0.479

High

250762

TERT
Telomerase reverse transcriptase

1

6

Small-scale

0.479

High

348419

MYC
Myc proto-oncogene protein

1

15

Small-scale

0.479

High

404134

JUN
Transcription factor Jun

1

6

Small-scale

0.479

High

472764

PTPRQ
Phosphatidylinositol phosphatase PTPRQ

1

20

Small-scale

0.479

High

629212

CCND1
G1/S-specific cyclin-D1

1

8

Small-scale

0.479

High

761852

ZO1
Tight junction protein ZO-1

1

9

Small-scale

0.479

High

787347

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

6

Small-scale

0.479

High

792152

HD
Huntingtin

1

3

Small-scale

0.479

High

804957

MERL
Merlin

1

6

Small-scale

0.479

High

857312

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

2

High-throughput

0.479

High

936201

KIFA3
Kinesin-associated protein 3

1

10

Small-scale

0.479

High

936672

ELAV1
ELAV-like protein 1

1

3

Small-scale

0.479

High

936716

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

9

Small-scale

0.479

High

956589

RGS14
Regulator of G-protein signaling 14

1

6

High-throughput

0.479

High

963717

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

4

High-throughput

0.479

High

970125

DACT3
Dapper homolog 3

1

3

Small-scale

0.479

High

970126

CUL4A
Cullin-4A

1

19

Small-scale

0.479

High

970127

SMCA4
Transcription activator BRG1

1

20

Small-scale

0.479

High

970128

FUBP2
Far upstream element-binding protein 2

1

5

Small-scale

0.479

High

970129

FBW1A
F-box/WD repeat-containing protein 1A

1

16

Small-scale

0.479

High

970130

CDKL5
Cyclin-dependent kinase-like 5

1

10

High-throughput

0.479

High

970131

LRRF1
Leucine-rich repeat flightless-interacting protein 1

1

2

Small-scale

0.479

High

970132

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

14

High-throughput

0.479

High

970133

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

7

Small-scale

0.479

High

970141

KIF3B
Kinesin-like protein KIF3B

1

3

Small-scale

0.479

High

970143

SF01
Splicing factor 1

1

7

Small-scale

0.479

High

970144

CDK6
Cyclin-dependent kinase 6

1

8

Small-scale

0.479

High

970145

NEB2
Neurabin-2

1

17

High-throughput

0.479

High

970146

DACT2
Dapper homolog 2

1

2

Small-scale

0.479

High

970147

FACD2
Fanconi anemia group D2 protein homolog

1

2

High-throughput

0.479

High

970149

NANOG
Homeobox protein NANOG

1

6

Small-scale

0.479

High

970152

Q8BPK8
Agenet-like domain-containing protein

1

5

High-throughput

0.479

High

970154

RPGF2
Rap guanine nucleotide exchange factor 2

1

3

Small-scale

0.479

High

970156

EED
Polycomb protein EED

1

18

High-throughput

0.479

High

970160

CNTP2
Contactin-associated protein-like 2

1

1

High-throughput

0.479

High

970167

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

Small-scale

0.479

High

970169

JAG1
Protein jagged-1

1

4

Small-scale

0.479

High

970170

NUMB
Protein numb homolog

1

3

Small-scale

0.479

High

970174

FOXO3
Forkhead box protein O3

1

9

Small-scale

0.479

High

292335

DCX
Neuronal migration protein doublecortin

1

0

Small-scale

0.458

High

352895

IFNB
Interferon beta

1

0

Small-scale

0.458

High

897336

CSN2
COP9 signalosome complex subunit 2

1

0

Small-scale

0.458

High

936557

MDFI
MyoD family inhibitor

1

0

Small-scale

0.458

High

970138

SC6A4
Sodium-dependent serotonin transporter

1

0

High-throughput

0.458

High

970175

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

9

High-throughput

0.457

High

729457

FMR1
Fragile X messenger ribonucleoprotein 1

1

5

High-throughput

0.445

High

970155

MK08
Mitogen-activated protein kinase 8

1

10

Small-scale

0.445

High

970157

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

6

Small-scale

0.445

High

970159

GRIP1
Glutamate receptor-interacting protein 1

1

17

Small-scale

0.445

High

970168

SRCN1
SRC kinase signaling inhibitor 1

1

3

High-throughput

0.445

High

970171

MK09
Mitogen-activated protein kinase 9

1

9

Small-scale

0.445

High

520204

PCP2
Purkinje cell protein 2

1

1

Small-scale

0.437

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024