Protein: AAKB1
5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb)

Gene: AAKB1, PRKAB1
Organism: Homo sapiens
Interactions: 220
UniProt ID: Q9Y478

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1025246

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

16

20

Small-scale

0.987

High

871085

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

13

16

Small-scale

0.982

High

871508

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

8

20

High-throughput

0.971

High

1355098

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

7

16

Small-scale

0.966

High

212559

AAKB2
5'-AMP-activated protein kinase subunit beta-2

5

13

High-throughput

0.930

High

1355094

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

5

16

Small-scale

0.928

High

549934

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

2

12

High-throughput

0.811

High

851754

NEK4
Serine/threonine-protein kinase Nek4

2

14

High-throughput

0.811

High

262331

ULK1
Serine/threonine-protein kinase ULK1

2

18

Small-scale

0.802

High

1302152

DCR1C
Protein artemis

4

1

High-throughput

0.694

High

230941

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

2

High-throughput

0.691

High

1301350

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

11

High-throughput

0.691

High

992214

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

3

1

High-throughput

0.667

High

1085561

MK06
Mitogen-activated protein kinase 6

1

5

High-throughput

0.656

High

1233573

MINK1
Misshapen-like kinase 1

1

0

High-throughput

0.656

High

924981

GRB2
Growth factor receptor-bound protein 2

2

2

Small-scale

0.631

High

829359

SYHM
Histidine--tRNA ligase, mitochondrial

2

2

High-throughput

0.628

High

1290910

TRI11
E3 ubiquitin-protein ligase TRIM11

2

3

High-throughput

0.628

High

1330839

TBB1
Tubulin beta-1 chain

2

3

High-throughput

0.628

High

1274617

TP4A1
Protein tyrosine phosphatase type IVA 1

1

1

High-throughput

0.618

High

1152216

LTOR1
Ragulator complex protein LAMTOR1

2

1

High-throughput

0.611

High

1223354

TRM44
Probable tRNA

2

0

High-throughput

0.602

High

556687

CBR1
Carbonyl reductase [NADPH] 1

2

0

High-throughput

0.585

High

1223638

ULK2
Serine/threonine-protein kinase ULK2

1

20

High-throughput

0.575

High

1377791

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

12

High-throughput

0.575

High

1350045

STIM2
Stromal interaction molecule 2

2

1

High-throughput

0.574

High

1357905

HDAC5
Histone deacetylase 5

1

1

Small-scale

0.561

High

683157

CASPE
Caspase-14

1

3

High-throughput

0.536

High

994034

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.536

High

1050097

SCRIB
Protein scribble homolog

1

3

High-throughput

0.536

High

1342567

M1IP1
Mid1-interacting protein 1

1

1

High-throughput

0.536

High

1377478

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

1

High-throughput

0.536

High

272317

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

1

High-throughput

0.515

High

533741

GYS1
Glycogen [starch] synthase, muscle

1

3

High-throughput

0.515

High

547291

EZRI
Ezrin

1

2

High-throughput

0.515

High

725272

MYH10
Myosin-10

1

4

High-throughput

0.515

High

200335

AP5Z1
AP-5 complex subunit zeta-1

1

0

High-throughput

0.513

High

218090

PEX1
Peroxisomal ATPase PEX1

1

0

High-throughput

0.513

High

804006

NSF
Vesicle-fusing ATPase

1

0

High-throughput

0.513

High

933681

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.513

High

1356728

PLAT4
Phospholipase A and acyltransferase 4

1

0

High-throughput

0.513

High

201479

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

2

Small-scale

0.501

High

1024116

ACACA
Acetyl-CoA carboxylase 1

1

1

Small-scale

0.501

High

862497

ACLY
ATP-citrate synthase

1

0

High-throughput

0.493

High

880200

SYMC
Methionine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

1329691

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

0

High-throughput

0.493

High

1060401

SL9A5
Sodium/hydrogen exchanger 5

1

1

High-throughput

0.489

High

396112

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

58259

SYTC2
Threonine--tRNA ligase 2, cytoplasmic

1

3

High-throughput

0.479

High

131118

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.479

High

132045

VMA5A
von Willebrand factor A domain-containing protein 5A

1

3

High-throughput

0.479

High

156383

PSA7
Proteasome subunit alpha type-7

1

2

High-throughput

0.479

High

177118

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

1

High-throughput

0.479

High

229152

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

236147

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

1

High-throughput

0.479

High

236541

CIDEA
Lipid transferase CIDEA

1

1

Small-scale

0.479

High

320932

HS74L
Heat shock 70 kDa protein 4L

1

1

High-throughput

0.479

High

403377

LA
Lupus La protein

1

1

High-throughput

0.479

High

545922

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

3

High-throughput

0.479

High

573120

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.479

High

574485

RL35A
Large ribosomal subunit protein eL33

1

1

High-throughput

0.479

High

580703

ML12A
Myosin regulatory light chain 12A

1

2

High-throughput

0.479

High

640166

MOES
Moesin

1

2

High-throughput

0.479

High

643806

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

3

High-throughput

0.479

High

678686

METK2
S-adenosylmethionine synthase isoform type-2

1

1

High-throughput

0.479

High

702997

KINH
Kinesin-1 heavy chain

1

1

High-throughput

0.479

High

708809

MCM5
DNA replication licensing factor MCM5

1

1

High-throughput

0.479

High

709129

MCM7
DNA replication licensing factor MCM7

1

1

High-throughput

0.479

High

780814

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

4

High-throughput

0.479

High

798789

PRS6B
26S proteasome regulatory subunit 6B

1

1

High-throughput

0.479

High

807072

RS9
Small ribosomal subunit protein uS4

1

2

High-throughput

0.479

High

816139

ATPO
ATP synthase subunit O, mitochondrial

1

1

High-throughput

0.479

High

845375

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.479

High

852757

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

1

High-throughput

0.479

High

857256

CAZA1
F-actin-capping protein subunit alpha-1

1

1

High-throughput

0.479

High

893776

PSA6
Proteasome subunit alpha type-6

1

2

High-throughput

0.479

High

895964

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

1

High-throughput

0.479

High

896572

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

1

High-throughput

0.479

High

901081

RHOA
Transforming protein RhoA

1

1

High-throughput

0.479

High

922486

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.479

High

932601

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

1

High-throughput

0.479

High

961031

CLH1
Clathrin heavy chain 1

1

1

High-throughput

0.479

High

963931

SET
Protein SET

1

2

High-throughput

0.479

High

1030058

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.479

High

1038095

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

High-throughput

0.479

High

1047976

COTL1
Coactosin-like protein

1

1

High-throughput

0.479

High

1062904

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

2

High-throughput

0.479

High

1064890

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1067864

PDIA6
Protein disulfide-isomerase A6

1

1

High-throughput

0.479

High

1082469

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.479

High

1113867

GRDN
Girdin

1

5

High-throughput

0.479

High

1132362

Q5T081
Regulator of chromosome condensation

1

1

High-throughput

0.479

High

1172405

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

1176336

CEP68
Centrosomal protein of 68 kDa

1

1

High-throughput

0.479

High

1184544

SYPM
Probable proline--tRNA ligase, mitochondrial

1

3

High-throughput

0.479

High

1242952

ABCF1
ATP-binding cassette sub-family F member 1

1

1

High-throughput

0.479

High

1257116

FNIP1
Folliculin-interacting protein 1

1

1

Small-scale

0.479

High

1284192

LRC59
Leucine-rich repeat-containing protein 59

1

2

High-throughput

0.479

High

1299150

IPO9
Importin-9

1

1

High-throughput

0.479

High

1303671

PHX2B
Paired mesoderm homeobox protein 2B

1

2

High-throughput

0.479

High

1303965

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

1

High-throughput

0.479

High

1312974

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

2

High-throughput

0.479

High

1314574

THIC
Acetyl-CoA acetyltransferase, cytosolic

1

1

High-throughput

0.479

High

1319161

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

1328472

ALX4
Homeobox protein aristaless-like 4

1

1

High-throughput

0.479

High

1336376

E41L5
Band 4.1-like protein 5

1

2

High-throughput

0.479

High

1344189

DDX21
Nucleolar RNA helicase 2

1

1

High-throughput

0.479

High

1350071

RCC2
Protein RCC2

1

1

High-throughput

0.479

High

1354447

DIC
Mitochondrial dicarboxylate carrier

1

4

High-throughput

0.479

High

1355474

DDX20
Probable ATP-dependent RNA helicase DDX20

1

1

High-throughput

0.479

High

1376984

RUVB2
RuvB-like 2

1

1

High-throughput

0.479

High

1377601

SF3B6
Splicing factor 3B subunit 6

1

1

High-throughput

0.479

High

136122

PDXK
Pyridoxal kinase

1

0

High-throughput

0.458

High

211769

BUD23
Probable 18S rRNA

1

0

High-throughput

0.458

High

256862

SOCS5
Suppressor of cytokine signaling 5

1

0

High-throughput

0.458

High

269092

CSDE1
Cold shock domain-containing protein E1

1

0

High-throughput

0.458

High

335579

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.458

High

337140

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.458

High

1356476

NXT1
NTF2-related export protein 1

1

0

High-throughput

0.458

High

1356479

NUDT5
ADP-sugar pyrophosphatase

1

0

High-throughput

0.458

High

378600

OAT
Ornithine aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

434508

FUMH
Fumarate hydratase, mitochondrial

1

0

High-throughput

0.458

High

440829

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

456031

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

488439

ACRO
Acrosin

1

0

High-throughput

0.458

High

516761

PABP1
Polyadenylate-binding protein 1

1

0

High-throughput

0.458

High

535966

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

571073

PYRG1
CTP synthase 1

1

0

High-throughput

0.458

High

621291

RIR1
Ribonucleoside-diphosphate reductase large subunit

1

0

High-throughput

0.458

High

669498

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.458

High

671599

KCY
UMP-CMP kinase

1

0

High-throughput

0.458

High

713655

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.458

High

715020

PROF2
Profilin-2

1

0

High-throughput

0.458

High

725618

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.458

High

739885

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.458

High

760410

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

768519

TYRP2
L-dopachrome tautomerase

1

0

High-throughput

0.458

High

800646

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

0

High-throughput

0.458

High

801801

RAGP1
Ran GTPase-activating protein 1

1

0

High-throughput

0.458

High

816373

PPCE
Prolyl endopeptidase

1

0

High-throughput

0.458

High

832065

PSB3
Proteasome subunit beta type-3

1

0

High-throughput

0.458

High

836692

GUAA
GMP synthase [glutamine-hydrolyzing]

1

0

High-throughput

0.458

High

838702

GDIB
Rab GDP dissociation inhibitor beta

1

0

High-throughput

0.458

High

839999

F10A1
Hsc70-interacting protein

1

0

High-throughput

0.458

High

840874

DYN2
Dynamin-2

1

0

High-throughput

0.458

High

878578

PSA
Puromycin-sensitive aminopeptidase

1

0

High-throughput

0.458

High

881070

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

885851

MTPN
Myotrophin

1

0

High-throughput

0.458

High

888467

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.458

High

902856

UFM1
Ubiquitin-fold modifier 1

1

0

High-throughput

0.458

High

934615

PA1B2
Platelet-activating factor acetylhydrolase IB subunit alpha2

1

0

High-throughput

0.458

High

950901

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.458

High

958556

CYC
Cytochrome c

1

0

High-throughput

0.458

High

964974

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.458

High

966794

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

0

High-throughput

0.458

High

967530

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

980037

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

0

High-throughput

0.458

High

1044585

FHL1
Four and a half LIM domains protein 1

1

0

High-throughput

0.458

High

1074278

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.458

High

1075594

TSN
Translin

1

0

High-throughput

0.458

High

1083060

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.458

High

1085382

FSCN1
Fascin

1

0

High-throughput

0.458

High

1102198

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

0

High-throughput

0.458

High

1119918

FA98B
Protein FAM98B

1

0

High-throughput

0.458

High

1151006

Q6FGG2
Vesicle-associated membrane protein 3

1

0

High-throughput

0.458

High

1184173

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

High-throughput

0.458

High

1230842

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.458

High

1291620

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.458

High

1295050

CK5P3
CDK5 regulatory subunit-associated protein 3

1

0

High-throughput

0.458

High

1300518

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.458

High

1316717

PCGF6
Polycomb group RING finger protein 6

1

0

High-throughput

0.458

High

1318557

API5
Apoptosis inhibitor 5

1

0

High-throughput

0.458

High

1331711

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1334976

GRPE1
GrpE protein homolog 1, mitochondrial

1

0

High-throughput

0.458

High

1335144

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

1350174

BCCIP
BRCA2 and CDKN1A-interacting protein

1

0

High-throughput

0.458

High

1354108

PEMT
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.458

High

1354231

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.458

High

1355603

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.458

High

1355701

TR112
Multifunctional methyltransferase subunit TRM112-like protein

1

0

High-throughput

0.458

High

1357844

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.458

High

1377059

NUDC
Nuclear migration protein nudC

1

0

High-throughput

0.458

High

1377655

RT16
Small ribosomal subunit protein bS16m

1

0

High-throughput

0.458

High

1377697

STRAP
Serine-threonine kinase receptor-associated protein

1

0

High-throughput

0.458

High

1377749

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.458

High

1350155

FNIP2
Folliculin-interacting protein 2

1

1

Small-scale

0.445

High

301342

MTCL2
Microtubule cross-linking factor 2

1

6

Small-scale

0.437

High

532030

PDIA4
Protein disulfide-isomerase A4

1

1

High-throughput

0.437

High

533569

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

671547

ECHM
Enoyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.437

High

778341

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

847402

SSRD
Translocon-associated protein subunit delta

1

1

High-throughput

0.437

High

901547

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

1

High-throughput

0.437

High

1286568

ENTR1
Endosome-associated-trafficking regulator 1

1

1

High-throughput

0.437

High

1343320

RTN4
Reticulon-4

1

4

High-throughput

0.437

High

245180

CUTA
Protein CutA

2

0

High-throughput

0.328

High

686266

GASR
Gastrin/cholecystokinin type B receptor

2

0

High-throughput

0.328

High

1149538

HEAT6
HEAT repeat-containing protein 6

2

0

High-throughput

0.328

High

306739

NDUA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

1

0

High-throughput

0.282

High

341325

FA10
Coagulation factor X

1

0

High-throughput

0.282

High

1250889

RFESD
Rieske domain-containing protein

1

0

High-throughput

0.279

Low

1356910

AT7L1
Ataxin-7-like protein 1

1

0

High-throughput

0.279

Low

1357528

PA2GD
Group IID secretory phospholipase A2

1

0

High-throughput

0.279

Low

179285

COPT1
High affinity copper uptake protein 1

1

0

Small-scale

0.261

Low

337266

AATM
Aspartate aminotransferase, mitochondrial

1

0

High-throughput

0.249

Low

875817

MFAP3
Microfibril-associated glycoprotein 3

1

0

High-throughput

0.249

Low

879727

ATPK
ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.249

Low

982787

PLP2
Proteolipid protein 2

1

0

High-throughput

0.249

Low

996023

DSC1
Desmocollin-1

1

0

High-throughput

0.249

Low

1114076

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

0

High-throughput

0.249

Low

1159134

EBLN2
Endogenous Bornavirus-like nucleoprotein 2

1

0

High-throughput

0.249

Low

1190632

CFA91
Cilia- and flagella-associated protein 91

1

0

High-throughput

0.249

Low

1201265

MGDP1
Magnesium-dependent phosphatase 1

1

0

High-throughput

0.249

Low

1241525

Q8NCK5
Glutamate-rich WD repeat-containing protein 1

1

0

High-throughput

0.249

Low

1330303

G3ST2
Galactose-3-O-sulfotransferase 2

1

0

High-throughput

0.249

Low

1335740

MRM3
rRNA methyltransferase 3, mitochondrial

1

0

High-throughput

0.249

Low

1348050

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

0

High-throughput

0.249

Low

1348848

CISD1
CDGSH iron-sulfur domain-containing protein 1

1

0

High-throughput

0.249

Low

1349484

CNIH4
Protein cornichon homolog 4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024