Protein: CDK8
Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8)

Gene: CDK8
Organism: Mus musculus
Interactions: 9
UniProt ID: Q8R3L8

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0004672 - protein kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1211125

MED13
Mediator of RNA polymerase II transcription subunit 13

1

7

Small-scale

0.618

High

1297618

ZN322
Zinc finger protein 322

1

1

Small-scale

0.618

High

59316

MED12
Mediator of RNA polymerase II transcription subunit 12

2

18

Small-scale

0.594

High

1222876

ERR2
Steroid hormone receptor ERR2

1

13

High-throughput

0.536

High

1235706

NIPBL
Nipped-B-like protein

1

6

Small-scale

0.500

High

1341561

MED15
Mediator of RNA polymerase II transcription subunit 15

1

4

Small-scale

0.500

High

1341562

SMC3
Structural maintenance of chromosomes protein 3

1

9

Small-scale

0.500

High

629398

PO5F1
POU domain, class 5, transcription factor 1

1

3

High-throughput

0.445

High

1190672

TF2L1
Transcription factor CP2-like protein 1

1

2

High-throughput

0.445

High


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Last updated: 11Aug2025