Protein: SMAD3
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3)

Gene: SMAD3
Organism: Homo sapiens
Interactions: 392
UniProt ID: P84022

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

950165

SMAD4
Mothers against decapentaplegic homolog 4

62

19

Small-scale

0.997

High

521255

SKI
Ski oncogene

16

16

Small-scale

0.987

High

313526

ZFYV9
Zinc finger FYVE domain-containing protein 9

10

12

Small-scale

0.978

High

950193

SMAD2
Mothers against decapentaplegic homolog 2

12

20

Small-scale

0.977

High

521343

SKIL
Ski-like protein

8

16

Small-scale

0.964

High

950140

SMAD3
Mothers against decapentaplegic homolog 3

5

19

Small-scale

0.918

High

171384

SMAD9
Mothers against decapentaplegic homolog 9

3

19

High-throughput

0.861

High

950194

SMAD1
Mothers against decapentaplegic homolog 1

2

19

Small-scale

0.783

High

950155

EP300
Histone acetyltransferase p300

19

20

Small-scale

0.765

High

950287

SMUF2
E3 ubiquitin-protein ligase SMURF2

13

20

Small-scale

0.761

High

950234

CBP
CREB-binding protein

10

19

Small-scale

0.754

High

950278

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

7

20

Small-scale

0.750

High

950328

TRI33
E3 ubiquitin-protein ligase TRIM33

7

11

Small-scale

0.736

High

808087

NEDD4
E3 ubiquitin-protein ligase NEDD4

6

20

Small-scale

0.734

High

950336

MAN1
Inner nuclear membrane protein Man1

6

14

Small-scale

0.733

High

435041

SP1
Transcription factor Sp1

6

5

Small-scale

0.731

High

125369

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

5

20

Small-scale

0.729

High

270777

FOXH1
Forkhead box protein H1

5

17

Small-scale

0.719

High

401843

JUN
Transcription factor Jun

5

10

Small-scale

0.718

High

738526

TGFR1
TGF-beta receptor type-1

5

20

Small-scale

0.714

High

167349

SMAD7
Mothers against decapentaplegic homolog 7

1

18

Small-scale

0.713

High

950197

HIF1A
Hypoxia-inducible factor 1-alpha

4

8

Small-scale

0.707

High

950182

CASL
Enhancer of filamentation 1

4

5

Small-scale

0.703

High

716989

CTNB1
Catenin beta-1

5

5

Small-scale

0.702

High

950208

RN111
E3 ubiquitin-protein ligase Arkadia

5

9

Small-scale

0.702

High

950255

ERBIN
Erbin

4

10

Small-scale

0.702

High

950167

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

4

1

Small-scale

0.701

High

950249

NED4L
E3 ubiquitin-protein ligase NEDD4-like

4

20

Small-scale

0.698

High

950342

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

4

13

Small-scale

0.696

High

487334

ANDR
Androgen receptor

3

14

Small-scale

0.690

High

950291

SMUF1
E3 ubiquitin-protein ligase SMURF1

4

20

Small-scale

0.683

High

950147

MECOM
Histone-lysine N-methyltransferase MECOM

3

18

Small-scale

0.683

High

950153

TLE5
TLE family member 5

3

1

High-throughput

0.683

High

950222

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

3

3

High-throughput

0.683

High

950237

KAT2B
Histone acetyltransferase KAT2B

4

13

Small-scale

0.680

High

822240

KC1D
Casein kinase I isoform delta

3

3

Small-scale

0.675

High

950242

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

3

7

Small-scale

0.672

High

170537

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

3

1

High-throughput

0.667

High

950262

SMAD5
Mothers against decapentaplegic homolog 5

1

19

Small-scale

0.665

High

950176

RUNX2
Runt-related transcription factor 2

3

16

Small-scale

0.664

High

950279

GO45
Golgin-45

3

0

High-throughput

0.658

High

950189

TGIF1
Homeobox protein TGIF1

3

11

Small-scale

0.656

High

837924

MEOX2
Homeobox protein MOX-2

2

6

High-throughput

0.654

High

950217

PHC2
Polyhomeotic-like protein 2

2

1

High-throughput

0.654

High

950159

NFIA
Nuclear factor 1 A-type

1

5

Small-scale

0.647

High

950168

HDAC1
Histone deacetylase 1

3

12

Small-scale

0.647

High

377251

GCR
Glucocorticoid receptor

2

14

Small-scale

0.646

High

950317

LEF1
Lymphoid enhancer-binding factor 1

2

20

Small-scale

0.646

High

206824

FOXO3
Forkhead box protein O3

2

18

Small-scale

0.641

High

950174

RUNX3
Runt-related transcription factor 3

3

16

Small-scale

0.640

High

950169

SNW1
SNW domain-containing protein 1

2

2

Small-scale

0.639

High

950240

IRF7
Interferon regulatory factor 7

2

4

Small-scale

0.639

High

950276

LACRT
Extracellular glycoprotein lacritin

3

0

High-throughput

0.638

High

950166

SQSTM
Sequestosome-1

2

3

Small-scale

0.631

High

950220

PIAS4
E3 SUMO-protein ligase PIAS4

2

16

Small-scale

0.631

High

950326

CHIP
E3 ubiquitin-protein ligase CHIP

2

6

Small-scale

0.629

High

200171

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

2

13

Small-scale

0.624

High

579191

ATF3
Cyclic AMP-dependent transcription factor ATF-3

2

14

Small-scale

0.624

High

835655

GSK3B
Glycogen synthase kinase-3 beta

2

8

Small-scale

0.624

High

950307

WWOX
WW domain-containing oxidoreductase

2

1

Small-scale

0.624

High

443164

NFIC
Nuclear factor 1 C-type

1

5

Small-scale

0.618

High

632690

TYY1
Transcriptional repressor protein YY1

2

11

Small-scale

0.611

High

658889

MK01
Mitogen-activated protein kinase 1

2

3

Small-scale

0.611

High

394530

A4
Amyloid-beta precursor protein

2

3

High-throughput

0.611

High

345397

FOS
Protein c-Fos

2

17

Small-scale

0.606

High

509931

VDR
Vitamin D3 receptor

2

11

Small-scale

0.606

High

950206

ZN774
Zinc finger protein 774

2

4

High-throughput

0.606

High

569586

CEBPB
CCAAT/enhancer-binding protein beta

2

8

Small-scale

0.602

High

585649

TFE3
Transcription factor E3

2

4

Small-scale

0.602

High

950248

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

20

Small-scale

0.602

High

571401

DDX5
Probable ATP-dependent RNA helicase DDX5

2

10

Small-scale

0.602

High

549567

VEGFA
Vascular endothelial growth factor A, long form

2

2

Small-scale

0.601

High

950289

PRD16
Histone-lysine N-methyltransferase PRDM16

2

13

Small-scale

0.601

High

231226

ZEB2
Zinc finger E-box-binding homeobox 2

2

15

Small-scale

0.600

High

749373

BRCA1
Breast cancer type 1 susceptibility protein

2

0

Small-scale

0.598

High

550361

ZEP1
Zinc finger protein 40

2

4

High-throughput

0.595

High

950345

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

2

7

Small-scale

0.595

High

642933

S10A4
Protein S100-A4

1

4

Small-scale

0.589

High

673387

MPIP1
M-phase inducer phosphatase 1

2

0

Small-scale

0.588

High

611420

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

2

12

Small-scale

0.586

High

547783

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

10

Small-scale

0.586

High

227166

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.584

High

397101

PAI1
Plasminogen activator inhibitor 1

2

3

Small-scale

0.584

High

575371

EGR1
Early growth response protein 1

2

6

Small-scale

0.584

High

740500

PPARG
Peroxisome proliferator-activated receptor gamma

2

14

Small-scale

0.584

High

950144

RUNX1
Runt-related transcription factor 1

2

16

Small-scale

0.584

High

950195

EZH2
Histone-lysine N-methyltransferase EZH2

2

11

Small-scale

0.584

High

594509

PSB1
Proteasome subunit beta type-1

2

0

High-throughput

0.580

High

950141

DAB2
Disabled homolog 2

1

2

Small-scale

0.578

High

950173

FHL3
Four and a half LIM domains protein 3

1

13

Small-scale

0.578

High

346519

MYC
Myc proto-oncogene protein

1

11

Small-scale

0.573

High

950245

RNF31
E3 ubiquitin-protein ligase RNF31

1

3

High-throughput

0.573

High

950264

MYD88
Myeloid differentiation primary response protein MyD88

1

4

High-throughput

0.573

High

950272

SETD2
Histone-lysine N-methyltransferase SETD2

1

11

High-throughput

0.573

High

950274

PP12C
Protein phosphatase 1 regulatory subunit 12C

1

5

High-throughput

0.573

High

950280

CHRD
Chordin

1

12

High-throughput

0.573

High

950339

T22D4
TSC22 domain family protein 4

1

2

High-throughput

0.573

High

197690

CRX
Cone-rod homeobox protein

1

7

High-throughput

0.573

High

950228

TEKT4
Tektin-4

1

1

High-throughput

0.573

High

950146

FLI1
Friend leukemia integration 1 transcription factor

1

4

High-throughput

0.568

High

271695

DEDD
Death effector domain-containing protein

1

0

Small-scale

0.561

High

170332

TIF1A
Transcription intermediary factor 1-alpha

1

13

Small-scale

0.561

High

386521

P53
Cellular tumor antigen p53

1

4

Small-scale

0.561

High

660114

RBL1
Retinoblastoma-like protein 1

1

1

Small-scale

0.561

High

727240

NU214
Nuclear pore complex protein Nup214

1

8

Small-scale

0.561

High

782518

HNF4A
Hepatocyte nuclear factor 4-alpha

1

10

Small-scale

0.561

High

804201

NOTC1
Neurogenic locus notch homolog protein 1

1

11

Small-scale

0.561

High

830916

CTCF
Transcriptional repressor CTCF

1

5

Small-scale

0.561

High

831878

CEBPD
CCAAT/enhancer-binding protein delta

1

14

Small-scale

0.561

High

835042

TSC2
Tuberin

1

1

Small-scale

0.561

High

847789

BRCA2
Breast cancer type 2 susceptibility protein

1

1

Small-scale

0.561

High

880680

HDAC4
Histone deacetylase 4

1

17

Small-scale

0.561

High

943108

KC1G2
Casein kinase I isoform gamma-2

1

13

Small-scale

0.561

High

950152

FOXM1
Forkhead box protein M1

1

4

Small-scale

0.561

High

950160

HYAL2
Hyaluronidase-2

1

2

Small-scale

0.561

High

950172

FHL1
Four and a half LIM domains protein 1

1

17

Small-scale

0.561

High

950180

FHL2
Four and a half LIM domains protein 2

1

15

Small-scale

0.561

High

950185

IMB1
Importin subunit beta-1

1

8

Small-scale

0.561

High

950219

MYCD
Myocardin

1

9

Small-scale

0.561

High

950223

EID2
EP300-interacting inhibitor of differentiation 2

1

2

Small-scale

0.561

High

950235

KAT6A
Histone acetyltransferase KAT6A

1

4

Small-scale

0.561

High

950246

OTUB1
Ubiquitin thioesterase OTUB1

1

5

Small-scale

0.561

High

950265

CITE2
Cbp/p300-interacting transactivator 2

1

2

Small-scale

0.561

High

950268

TRI62
E3 ubiquitin-protein ligase TRIM62

1

2

Small-scale

0.561

High

950296

SH22A
SH2 domain-containing protein 2A

1

6

Small-scale

0.561

High

950322

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

16

Small-scale

0.561

High

950323

APC10
Anaphase-promoting complex subunit 10

1

3

Small-scale

0.561

High

950330

HDAC5
Histone deacetylase 5

1

17

Small-scale

0.561

High

950349

PIAS3
E3 SUMO-protein ligase PIAS3

1

16

Small-scale

0.561

High

950273

DOCK9
Dedicator of cytokinesis protein 9

1

4

Small-scale

0.554

High

471688

SBK3
Uncharacterized serine/threonine-protein kinase SBK3

2

10

High-throughput

0.553

High

950198

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

1

0

High-throughput

0.549

High

950200

ZC12A
Endoribonuclease ZC3H12A

1

0

High-throughput

0.549

High

181600

CFLAR
CASP8 and FADD-like apoptosis regulator

1

1

High-throughput

0.541

High

198799

HXC11
Homeobox protein Hox-C11

1

18

High-throughput

0.541

High

257463

CREST
Calcium-responsive transactivator

1

5

High-throughput

0.541

High

279288

DNJB5
DnaJ homolog subfamily B member 5

1

4

High-throughput

0.541

High

316325

TYDP2
Tyrosyl-DNA phosphodiesterase 2

1

1

High-throughput

0.541

High

612839

FBLN1
Fibulin-1

1

8

High-throughput

0.541

High

650954

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.541

High

899918

ISL1
Insulin gene enhancer protein ISL-1

1

3

High-throughput

0.541

High

903883

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

1

High-throughput

0.541

High

950148

TF65
Transcription factor p65

1

7

High-throughput

0.541

High

950179

GIT2
ARF GTPase-activating protein GIT2

1

7

High-throughput

0.541

High

950269

RIOK2
Serine/threonine-protein kinase RIO2

1

1

High-throughput

0.541

High

950284

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

3

High-throughput

0.541

High

950196

E2F4
Transcription factor E2F4

1

0

Small-scale

0.537

High

950243

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.536

High

485057

GLI2
Zinc finger protein GLI2

1

8

Small-scale

0.536

High

950149

SRY
Sex-determining region Y protein

1

13

Small-scale

0.536

High

950204

KCD16
BTB/POZ domain-containing protein KCTD16

1

2

High-throughput

0.536

High

950214

LSR
Lipolysis-stimulated lipoprotein receptor

1

2

High-throughput

0.536

High

950218

TM192
Transmembrane protein 192

1

2

High-throughput

0.536

High

950299

HINT3
Adenosine 5'-monophosphoramidase HINT3

1

1

High-throughput

0.536

High

950316

ZF69B
Zinc finger protein 69 homolog B

1

2

High-throughput

0.536

High

921219

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.529

High

178146

IPO8
Importin-8

1

6

Small-scale

0.527

High

566747

JUNB
Transcription factor JunB

1

9

Small-scale

0.527

High

950201

CPTP
Ceramide-1-phosphate transfer protein

1

0

High-throughput

0.518

High

950238

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.518

High

950305

AATF
Protein AATF

1

0

High-throughput

0.518

High

61975

FA83G
Protein FAM83G

1

2

Small-scale

0.515

High

167520

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

8

Small-scale

0.515

High

211157

BUB3
Mitotic checkpoint protein BUB3

1

5

Small-scale

0.515

High

231088

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

1

Small-scale

0.515

High

243366

DNJA2
DnaJ homolog subfamily A member 2

1

5

Small-scale

0.515

High

516464

PABP1
Polyadenylate-binding protein 1

1

1

Small-scale

0.515

High

556433

ITB4
Integrin beta-4

1

2

Small-scale

0.515

High

621777

PRTN3
Myeloblastin

1

5

Small-scale

0.515

High

641717

U2AF2
Splicing factor U2AF 65 kDa subunit

1

4

Small-scale

0.515

High

665859

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

2

Small-scale

0.515

High

724531

IRS1
Insulin receptor substrate 1

1

5

Small-scale

0.515

High

855786

VAV2
Guanine nucleotide exchange factor VAV2

1

4

Small-scale

0.515

High

891691

ACTB
Actin, cytoplasmic 1

1

1

Small-scale

0.515

High

902875

DCAF7
DDB1- and CUL4-associated factor 7

1

2

Small-scale

0.515

High

950142

FOXO4
Forkhead box protein O4

1

18

Small-scale

0.515

High

950156

SRBP2
Sterol regulatory element-binding protein 2

1

14

Small-scale

0.515

High

950171

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

15

Small-scale

0.515

High

950175

KLF5
Krueppel-like factor 5

1

11

Small-scale

0.515

High

950183

DHX8
ATP-dependent RNA helicase DHX8

1

2

Small-scale

0.515

High

950190

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

3

Small-scale

0.515

High

950224

PJA1
E3 ubiquitin-protein ligase Praja-1

1

8

Small-scale

0.515

High

950229

ATX2L
Ataxin-2-like protein

1

1

Small-scale

0.515

High

950230

PSPC1
Paraspeckle component 1

1

5

Small-scale

0.515

High

950253

MED15
Mediator of RNA polymerase II transcription subunit 15

1

16

Small-scale

0.515

High

950259

HTF4
Transcription factor 12

1

2

Small-scale

0.515

High

950260

NOTC4
Neurogenic locus notch homolog protein 4

1

11

Small-scale

0.515

High

950266

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

1

Small-scale

0.515

High

950270

SARG
Specifically androgen-regulated gene protein

1

1

Small-scale

0.515

High

950292

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

2

Small-scale

0.515

High

950293

E41L5
Band 4.1-like protein 5

1

2

Small-scale

0.515

High

950306

MTMR4
Myotubularin-related protein 4

1

9

Small-scale

0.515

High

950314

DACH1
Dachshund homolog 1

1

2

Small-scale

0.515

High

950329

CD11A
Cyclin-dependent kinase 11A

1

3

Small-scale

0.515

High

950333

SIK3
Serine/threonine-protein kinase SIK3

1

3

Small-scale

0.515

High

950335

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

12

Small-scale

0.515

High

950343

YTHD2
YTH domain-containing family protein 2

1

1

Small-scale

0.515

High

568627

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

13

High-throughput

0.515

High

655315

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

2

High-throughput

0.515

High

667450

CASP1
Caspase-1

1

1

High-throughput

0.515

High

950151

APLP2
Amyloid beta precursor like protein 2

1

3

High-throughput

0.515

High

950231

JPH3
Junctophilin-3

1

2

High-throughput

0.515

High

950331

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

2

High-throughput

0.515

High

456848

FURIN
Furin

1

0

High-throughput

0.513

High

672653

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.513

High

950288

UD110
UDP-glucuronosyltransferase 1A10

1

0

High-throughput

0.513

High

121735

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

4

High-throughput

0.508

High

231294

GANP
Germinal-center associated nuclear protein

1

5

High-throughput

0.508

High

442065

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

8

High-throughput

0.508

High

523670

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.508

High

598062

FLNA
Filamin-A

1

4

High-throughput

0.508

High

602828

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

1

High-throughput

0.508

High

672084

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

4

High-throughput

0.508

High

846669

ZNF83
Zinc finger protein 83

1

3

High-throughput

0.508

High

950150

ZBT16
Zinc finger and BTB domain-containing protein 16

1

4

High-throughput

0.508

High

950161

ANK3
Ankyrin-3

1

3

High-throughput

0.508

High

950163

PAPP1
Pappalysin-1

1

10

High-throughput

0.508

High

950184

NCOA6
Nuclear receptor coactivator 6

1

5

High-throughput

0.508

High

950199

SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

1

9

High-throughput

0.508

High

950205

PLAG1
Zinc finger protein PLAG1

1

7

High-throughput

0.508

High

950210

CXXC5
CXXC-type zinc finger protein 5

1

3

High-throughput

0.508

High

950213

ZN329
Zinc finger protein 329

1

2

High-throughput

0.508

High

950257

RANB9
Ran-binding protein 9

1

9

High-throughput

0.508

High

950263

EPAS1
Endothelial PAS domain-containing protein 1

1

8

High-throughput

0.508

High

950277

SP130
Histone deacetylase complex subunit SAP130

1

4

High-throughput

0.508

High

950298

HEYL
Hairy/enhancer-of-split related with YRPW motif-like protein

1

6

High-throughput

0.508

High

950319

GGA1
ADP-ribosylation factor-binding protein GGA1

1

6

High-throughput

0.508

High

950321

PRDM4
PR domain zinc finger protein 4

1

2

High-throughput

0.508

High

950324

PLAL1
Zinc finger protein PLAGL1

1

8

High-throughput

0.508

High

950325

KMT2B
Histone-lysine N-methyltransferase 2B

1

14

High-throughput

0.508

High

950334

KDM2A
Lysine-specific demethylase 2A

1

3

High-throughput

0.508

High

950341

MTF2
Metal-response element-binding transcription factor 2

1

3

High-throughput

0.508

High

950344

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

4

High-throughput

0.508

High

950346

GMEB1
Glucocorticoid modulatory element-binding protein 1

1

1

High-throughput

0.508

High

150693

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

18

Small-scale

0.501

High

169276

MDM4
Protein Mdm4

1

1

Small-scale

0.501

High

278264

PIAS2
E3 SUMO-protein ligase PIAS2

1

16

Small-scale

0.501

High

411672

LCK
Tyrosine-protein kinase Lck

1

2

Small-scale

0.501

High

515398

CDK4
Cyclin-dependent kinase 4

1

3

Small-scale

0.501

High

568085

JUND
Transcription factor JunD

1

10

Small-scale

0.501

High

618604

IF4B
Eukaryotic translation initiation factor 4B

1

2

Small-scale

0.501

High

625355

CDK2
Cyclin-dependent kinase 2

1

2

Small-scale

0.501

High

728599

PPM1A
Protein phosphatase 1A

1

2

Small-scale

0.501

High

787205

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

Small-scale

0.501

High

826257

CDK8
Cyclin-dependent kinase 8

1

10

Small-scale

0.501

High

831213

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

Small-scale

0.501

High

834584

NU153
Nuclear pore complex protein Nup153

1

8

Small-scale

0.501

High

841653

CDK9
Cyclin-dependent kinase 9

1

7

Small-scale

0.501

High

898101

MAX
Protein max

1

9

Small-scale

0.501

High

950158

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

Small-scale

0.501

High

950226

PARD3
Partitioning defective 3 homolog

1

6

Small-scale

0.501

High

950258

SIN3A
Paired amphipathic helix protein Sin3a

1

1

Small-scale

0.501

High

950281

HIPK2
Homeodomain-interacting protein kinase 2

1

18

Small-scale

0.501

High

950318

DNM3L
DNA

1

2

Small-scale

0.501

High

950301

RNC
Ribonuclease 3

1

3

Small-scale

0.500

High

573222

TCPA
T-complex protein 1 subunit alpha

1

0

Small-scale

0.493

High

736400

RL4
Large ribosomal subunit protein uL4

1

0

Small-scale

0.493

High

760007

RL3
Large ribosomal subunit protein uL3

1

0

Small-scale

0.493

High

400849

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.486

High

950154

PCDH1
Protocadherin-1

1

0

High-throughput

0.486

High

950164

TMED1
Transmembrane emp24 domain-containing protein 1

1

0

High-throughput

0.486

High

950181

IL27B
Interleukin-27 subunit beta

1

0

High-throughput

0.486

High

950211

KANL1
KAT8 regulatory NSL complex subunit 1

1

0

High-throughput

0.486

High

950286

VISTA
V-type immunoglobulin domain-containing suppressor of T-cell activation

1

0

High-throughput

0.486

High

950311

CFDP1
Craniofacial development protein 1

1

0

High-throughput

0.486

High

120145

TLR4
Toll-like receptor 4

1

1

High-throughput

0.481

High

341369

PLMN
Plasminogen

1

3

High-throughput

0.481

High

678266

COR1A
Coronin-1A

1

1

High-throughput

0.481

High

950188

ZMY11
Zinc finger MYND domain-containing protein 11

1

20

High-throughput

0.481

High

950232

ZCH14
Zinc finger CCHC domain-containing protein 14

1

4

High-throughput

0.481

High

950302

UBQL4
Ubiquilin-4

1

6

High-throughput

0.481

High

950303

FAME
Factor associated with metabolism and energy

1

1

High-throughput

0.481

High

950310

DNJB4
DnaJ homolog subfamily B member 4

1

4

High-throughput

0.481

High

950320

PARP4
Protein mono-ADP-ribosyltransferase PARP4

1

1

High-throughput

0.481

High

950251

XPO6
Exportin-6

1

0

Small-scale

0.480

High

122659

MEN1
Menin

1

5

Small-scale

0.479

High

133977

DDX3X
ATP-dependent RNA helicase DDX3X

1

11

Small-scale

0.479

High

146196

ARI1A
AT-rich interactive domain-containing protein 1A

1

17

Small-scale

0.479

High

157197

BACH1
Transcription regulator protein BACH1

1

6

Small-scale

0.479

High

159959

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

9

Small-scale

0.479

High

165842

KDM6B
Lysine-specific demethylase 6B

1

10

Small-scale

0.479

High

181693

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

11

Small-scale

0.479

High

203663

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

6

Small-scale

0.479

High

265317

MED24
Mediator of RNA polymerase II transcription subunit 24

1

5

Small-scale

0.479

High

270496

MED6
Mediator of RNA polymerase II transcription subunit 6

1

2

Small-scale

0.479

High

271070

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

13

Small-scale

0.479

High

358494

CO1A1
Collagen alpha-1(I) chain

1

16

Small-scale

0.479

High

369398

ESR1
Estrogen receptor

1

14

Small-scale

0.479

High

456545

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

7

Small-scale

0.479

High

475623

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

7

Small-scale

0.479

High

487942

RARA
Retinoic acid receptor alpha

1

11

Small-scale

0.479

High

600125

TAF1
Transcription initiation factor TFIID subunit 1

1

20

Small-scale

0.479

High

610353

CBL
E3 ubiquitin-protein ligase CBL

1

3

Small-scale

0.479

High

641369

PAX6
Paired box protein Pax-6

1

4

Small-scale

0.479

High

668593

PML
Protein PML

1

7

Small-scale

0.479

High

672809

CDC27
Cell division cycle protein 27 homolog

1

6

Small-scale

0.479

High

681788

AKT1
RAC-alpha serine/threonine-protein kinase

1

9

Small-scale

0.479

High

714183

HSP74
Heat shock 70 kDa protein 4

1

1

Small-scale

0.479

High

719445

MERL
Merlin

1

2

High-throughput

0.479

High

727962

SOX11
Transcription factor SOX-11

1

16

Small-scale

0.479

High

738442

ACV1B
Activin receptor type-1B

1

20

Small-scale

0.479

High

739949

TGFR2
TGF-beta receptor type-2

1

20

Small-scale

0.479

High

741024

ZEB1
Zinc finger E-box-binding homeobox 1

1

20

Small-scale

0.479

High

758187

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

Small-scale

0.479

High

780958

ID1
DNA-binding protein inhibitor ID-1

1

1

Small-scale

0.479

High

782329

KDM5C
Lysine-specific demethylase 5C

1

1

Small-scale

0.479

High

805391

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

17

High-throughput

0.479

High

808511

YAP1
Transcriptional coactivator YAP1

1

20

Small-scale

0.479

High

818790

SOX9
Transcription factor SOX-9

1

17

Small-scale

0.479

High

841379

TOB1
Protein Tob1

1

11

Small-scale

0.479

High

846924

SMCA4
Transcription activator BRG1

1

2

Small-scale

0.479

High

877694

FOXA1
Hepatocyte nuclear factor 3-alpha

1

11

Small-scale

0.479

High

885155

FOXL2
Forkhead box protein L2

1

7

Small-scale

0.479

High

924475

GRB2
Growth factor receptor-bound protein 2

1

4

High-throughput

0.479

High

941887

PITX1
Pituitary homeobox 1

1

5

Small-scale

0.479

High

950143

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

5

Small-scale

0.479

High

950145

RELB
Transcription factor RelB

1

7

Small-scale

0.479

High

950157

FOXO1
Forkhead box protein O1

1

18

Small-scale

0.479

High

950162

CDC16
Cell division cycle protein 16 homolog

1

6

Small-scale

0.479

High

950170

CUL1
Cullin-1

1

7

Small-scale

0.479

High

950177

NFYC
Nuclear transcription factor Y subunit gamma

1

2

Small-scale

0.479

High

950178

ARHG7
Rho guanine nucleotide exchange factor 7

1

2

Small-scale

0.479

High

950187

RBBP5
Retinoblastoma-binding protein 5

1

3

Small-scale

0.479

High

950192

NCOA1
Nuclear receptor coactivator 1

1

9

Small-scale

0.479

High

950203

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

950207

TAF2
Transcription initiation factor TFIID subunit 2

1

1

Small-scale

0.479

High

950209

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

950212

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

3

Small-scale

0.479

High

950215

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

3

Small-scale

0.479

High

950225

SMRC2
SWI/SNF complex subunit SMARCC2

1

16

Small-scale

0.479

High

950236

KAT2A
Histone acetyltransferase KAT2A

1

20

Small-scale

0.479

High

950239

SMRC1
SWI/SNF complex subunit SMARCC1

1

13

Small-scale

0.479

High

950241

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

7

Small-scale

0.479

High

950244

MRTFA
Myocardin-related transcription factor A

1

7

Small-scale

0.479

High

950247

PDLI5
PDZ and LIM domain protein 5

1

7

Small-scale

0.479

High

950252

CIC
Protein capicua homolog

1

17

High-throughput

0.479

High

950256

TRIB3
Tribbles homolog 3

1

11

Small-scale

0.479

High

950261

PITX2
Pituitary homeobox 2

1

5

Small-scale

0.479

High

950267

OVOL2
Transcription factor Ovo-like 2

1

10

Small-scale

0.479

High

950275

TGIF2
Homeobox protein TGIF2

1

11

Small-scale

0.479

High

950282

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.479

High

950283

RGCC
Regulator of cell cycle RGCC

1

1

Small-scale

0.479

High

950285

RANB3
Ran-binding protein 3

1

1

Small-scale

0.479

High

950290

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

3

Small-scale

0.479

High

950297

MED4
Mediator of RNA polymerase II transcription subunit 4

1

3

Small-scale

0.479

High

950300

DDX4
Probable ATP-dependent RNA helicase DDX4

1

11

Small-scale

0.479

High

950308

IL37
Interleukin-37

1

1

Small-scale

0.479

High

950312

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

950332

FBW1A
F-box/WD repeat-containing protein 1A

1

5

Small-scale

0.479

High

950337

MED16
Mediator of RNA polymerase II transcription subunit 16

1

2

Small-scale

0.479

High

950338

STRAP
Serine-threonine kinase receptor-associated protein

1

8

Small-scale

0.479

High

950340

GRIP1
Glutamate receptor-interacting protein 1

1

2

Small-scale

0.479

High

950348

NCOA3
Nuclear receptor coactivator 3

1

10

Small-scale

0.479

High

274527

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

3

Small-scale

0.470

High

950250

CSMD1
CUB and sushi domain-containing protein 1

1

6

Small-scale

0.470

High

950347

SQOR
Sulfide:quinone oxidoreductase, mitochondrial

1

1

Small-scale

0.470

High

92820

E9PSE9
Coiled-coil domain containing 198

1

1

High-throughput

0.470

High

396661

CP11A
Cholesterol side-chain cleavage enzyme, mitochondrial

1

3

High-throughput

0.464

High

364547

TRFE
Serotransferrin

1

0

High-throughput

0.460

High

376451

APOB
Apolipoprotein B-100

1

0

High-throughput

0.460

High

950233

PROX1
Prospero homeobox protein 1

1

0

High-throughput

0.460

High

950313

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.460

High

238456

MAFK
Transcription factor MafK

1

0

Small-scale

0.458

High

324343

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

351352

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

950186

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

950191

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.458

High

950227

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

950254

Q96RS2
Small ribosomal subunit protein uS2

1

0

Small-scale

0.458

High

950327

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

0

High-throughput

0.458

High

799081

NKX21
Homeobox protein Nkx-2.1

1

9

Small-scale

0.457

High

150947

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

11

Small-scale

0.445

High

950294

JPH1
Junctophilin-1

1

1

Small-scale

0.445

High

950309

I36RA
Interleukin-36 receptor antagonist protein

1

1

Small-scale

0.445

High

341200

HPT
Haptoglobin

1

3

High-throughput

0.439

High

441720

CFAH
Complement factor H

1

10

High-throughput

0.439

High

483629

CSH2
Chorionic somatomammotropin hormone 2

1

4

High-throughput

0.439

High

100679

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

950202

OTUD1
OTU domain-containing protein 1

1

1

Small-scale

0.437

High

531346

K1C10
Keratin, type I cytoskeletal 10

1

0

Small-scale

0.426

High

724644

GDE
Glycogen debranching enzyme

1

0

Small-scale

0.426

High

944115

P78451
Somatomammotropin

1

4

High-throughput

0.417

High

950221

CCD33
Coiled-coil domain-containing protein 33

4

0

High-throughput

0.362

High

950216

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

719799

RECO
Recoverin

1

0

High-throughput

0.282

High

950304

EVA1B
Protein eva-1 homolog B

1

0

High-throughput

0.279

Low

950271

RFIP5
Rab11 family-interacting protein 5

1

0

Small-scale

0.269

Low

950315

SIA7B
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

1

0

High-throughput

0.265

Low

576269

LBP
Lipopolysaccharide-binding protein

1

0

High-throughput

0.251

Low

950295

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.251

Low

450646

PAEP
Glycodelin

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024