Protein: ADPRS
ADP-ribosylhydrolase ARH3 (ADP-ribose glycohydrolase ARH3) (ADP-ribosylhydrolase 3) (O-acetyl-ADP-ribose deacetylase ARH3) (EC 3.5.1.-) (Poly(ADP-ribose) glycohydrolase ARH3) (EC 3.2.1.143) ([Protein ADP-ribosylarginine] hydrolase-like protein 2) ([Protein ADP-ribosylserine] hydrolase) (EC 3.2.2.-)

Gene: ADPRS
Organism: Homo sapiens
Interactions: 28
UniProt ID: Q9NX46

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004649 - poly(ADP-ribose) glycohydrolase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

332456

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

2

0

High-throughput

0.580

High

1447539

PRDM5
PR domain zinc finger protein 5

2

0

High-throughput

0.580

High

415896

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.541

High

1258753

F10C1
Protein FRA10AC1

1

0

High-throughput

0.518

High

1357872

HEXD
Hexosaminidase D

1

0

High-throughput

0.518

High

1347879

RIN3
Ras and Rab interactor 3

1

0

High-throughput

0.513

High

1439704

NDF4
Neurogenic differentiation factor 4

1

0

High-throughput

0.513

High

1451776

ARIP4
Helicase ARIP4

1

0

High-throughput

0.513

High

373303

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

425648

ISG15
Ubiquitin-like protein ISG15

1

0

High-throughput

0.458

High

1255809

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

106739

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

1380598

IGSF8
Immunoglobulin superfamily member 8

1

1

High-throughput

0.437

High

295646

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.426

High

298102

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.426

High

330345

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.426

High

404932

PRIO
Major prion protein

1

0

High-throughput

0.426

High

967179

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

0

High-throughput

0.426

High

1392573

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.426

High

1398981

FRMD6
FERM domain-containing protein 6

1

0

High-throughput

0.426

High

1451775

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.426

High

553414

FCG2A
Low affinity immunoglobulin gamma Fc region receptor II-a

1

0

High-throughput

0.249

Low

261295

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

388561

CRP

1

0

High-throughput

0.232

Low

955897

GMFB
Glia maturation factor beta

1

0

High-throughput

0.232

Low

999419

HBB
Hemoglobin subunit beta

1

0

High-throughput

0.232

Low

1329986

CJ053
UPF0728 protein C10orf53

1

0

High-throughput

0.232

Low

1365686

LAR4B
La-related protein 4B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025