Protein: LE418
Protein let-418 (Lethal protein 418)

Gene: LE418, let-418
Organism: Caenorhabditis elegans
Interactions: 14
UniProt ID: G5EBZ4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0004386 - helicase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

110292

LIN53
Probable histone-binding protein lin-53

2

20

Small-scale

0.754

High

63432

SIN3
Paired amphipathic helix protein sin-3

1

14

High-throughput

0.618

High

110290

HDA1
Histone deacetylase 1

1

20

Small-scale

0.618

High

110291

HCP3
Histone H3-like centromeric protein hcp-3

1

20

Small-scale

0.618

High

110294

Q86S28
DIOX_N domain-containing protein

1

20

Small-scale

0.618

High

110293

MEP1
MOG interacting and ectopic P-granules protein 1

2

1

Small-scale

0.611

High

110295

PIE1
Pharynx and intestine in excess protein 1

1

1

Small-scale

0.536

High

110286

G5EC16
Survival motor neuron protein

1

0

Small-scale

0.529

High

110287

G5EC43
Kinesin-like protein

1

14

High-throughput

0.479

High

110288

G5EDL0
ETS domain-containing protein

1

20

Small-scale

0.479

High

110289

MES2
Histone-lysine N-methyltransferase mes-2

1

20

Small-scale

0.479

High

110297

MBK2
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2

1

3

High-throughput

0.479

High

110298

KDM1A
Lysine-specific histone demethylase 1

1

9

Small-scale

0.479

High

110296

Q9TXM1
Uncharacterized protein

1

3

High-throughput

0.437

High


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Last updated: 11Aug2025